معرفی
Justin English serves as Assistant Professor of Biochemistry at the University of Utah School of Medicine, where he develops molecular tools to investigate human health and disease mechanisms through directed evolution and protein engineering approaches.
Education:
- B.A. from Cornell University
- Ph.D. from University of North Carolina at Chapel Hill
Research Focus:
Dr. English's laboratory specializes in Directed Evolution and Protein Engineering to create molecular tools for studying G-protein Coupled Receptors (GPCRs), cell signaling pathways, and neuroscience applications. His work integrates synthetic biology with classical pharmacology to develop innovative platforms like VEGAS for mammalian cell evolution and TRUPATH for GPCR transducerome analysis, with significant implications for drug discovery and therapeutic development.
Publication Trends:
Analysis of his 2019-2025 publications reveals consistent focus on GPCR biology, featuring breakthroughs in biosensor development (nanobody-based receptor monitoring), chemogenetic tools (BioTAC system), and high-throughput screening platforms. His research demonstrates strong translational potential in neuroscience, particularly through engineered mouse models for psychedelic drug studies and molecular tools for mapping small-molecule interactomes.
Research Environment:
Dr. English leads an active laboratory within the University of Utah's Department of Biochemistry, leveraging institutional core facilities for biochemical and molecular studies. His research program maintains strong collaborative ties with neuroscience and pharmacology groups, with ongoing projects focused on advancing molecular engineering techniques for biomedical applications as detailed on his lab website.
