جست‌وجوی استاد و پژوهشگر

Rajat Singhمشاهده پروفایل

استاد مدعو

• Autophagy
• Metabolic Regulation
• Lipid Metabolism
• +۳ مورد دیگر

Rajat Singh, MB, BS, MD is an Adjunct Professor at the University of California Los Angeles (UCLA), holding appointments in the Department of Medicine (Endocrinology) and the Department of Developmental & Molecular Biology. His research focuses on autophagy's role in metabolic regulation across physiology, obesity, and aging. Singh leads the Lab of Rajat Singh, investigating how autophagy modulates lipid metabolism, energy homeostasis, and neural mechanisms controlling feeding behavior. His work employs biochemical, immunohistochemical, and in vivo approaches in mouse models to study organ-specific autophagy effects. Key areas include understanding how autophagy failure contributes to metabolic aging and developing interventions to counteract metabolic decline through dietary strategies like time-restricted feeding. His lab also explores autophagy's interplay with circadian rhythms and mitochondrial dynamics in metabolic disorders. Research Interests : Singh’s work spans autophagy mechanisms, lipophagy, metabolic aging, hypothalamic signaling, and the impact of dietary interventions. He investigates how autophagy regulates lipid storage mobilization in neurons and peripheral tissues, linking these processes to obesity, diabetes, and age-related metabolic dysfunction. Recent studies highlight autophagy’s role in circadian clock regulation and mitochondrial health, with implications for neurodegenerative diseases and cardiovascular health. Labs/Teams : The Lab of Rajat Singh integrates interdisciplinary approaches to study metabolic and cellular biology, collaborating on projects involving autophagy’s role in energy balance, aging, and disease. Key collaborations include work on autophagy-circadian clock interactions and mitochondrial quality control in metabolic stress.

Jasenka Guduric-Fuchsمشاهده پروفایل

پژوهشگر ارشد

• MicroRNA Biology
• Endothelial Cell Regeneration
• Diabetic Retinopathy
• +۴ مورد دیگر

Jasenka Guduric-Fuchs is a Research Fellow at the Wellcome Wolfson Institute for Experimental Medicine, Queen's University Belfast. Her research focuses on microRNA regulation in endothelial cells, diabetic retinopathy pathogenesis, and vascular regeneration therapies. Key investigations include endothelial progenitor dysfunction in diabetes, epigenetic dysregulation in hyperglycemia, and pentraxin-mediated retinal inflammation. Develops stem cell-based approaches for ischemic retinopathies and studies extracellular vesicle signaling in age-related macular degeneration. Publications emphasize molecular mechanisms of vascular aging, microRNA control of angiogenesis, and translational applications for ocular diseases. Recent work identifies novel senescence signatures and explores NOX4 signaling restoration for diabetic vascular repair. Collaborates internationally on retinal vascular biology projects. Research contributes to therapeutic development for diabetic complications and retinal degenerative diseases.

Michelle Naughtonمشاهده پروفایل

پژوهشگر ارشد

• Neuroimmunology
• Multiple Sclerosis
• Myeloid-Derived Suppressor Cells
• +۲ مورد دیگر

Dr. Michelle Naughton is a Research Fellow at Queen's University Belfast's Wellcome Wolfson Institute for Experimental Medicine, specializing in neuroimmunology and multiple sclerosis mechanisms. Her work examines myeloid-derived suppressor cells, compartmentalized inflammation, and tertiary lymphoid structures in MS pathology. Key research themes: Myeloid cell contributions to MS clinical severity Complement system activation in grey matter lesions Microglial responses to autoantibodies CCN3 matricellular protein dynamics Recent publications (2023) establish relationships between MDSC-like cells and disease progression. Recognized with the 2023 British Society for Immunology Team Award and 2021 QUB Research Culture Prize. Serves on the MS Society scientific advisory committee.

• Cancer Biology
• Epigenetics
• Molecular Biology
• +۳ مورد دیگر

Kathryn J. Leyva, Ph.D., is the Chair of the Microbiology & Immunology Department at Midwestern University, holding concurrent professorships across multiple colleges including the Arizona College of Podiatric Medicine, College of Veterinary Medicine, and College of Pharmacy. She has held academic positions since 1999, progressing from Assistant Professor (1999–2004) to Associate Professor (2004–2011), then Professor (2011–present), and finally Department Chair since 2018. Dr. Leyva’s research focuses on three core areas: miRNA in cancer progression, epigenetic regulation of epithelial-mesenchymal transition (EMT), and progranulin-lysosomal dysfunction in neurodegenerative diseases. Her work integrates molecular, cellular, and clinical approaches, with notable contributions to understanding HDAC inhibitors, cancer metastasis, and zebrafish models of wound healing. She leads a grant-funded project exploring progranulin and lysosomal pH in neurodegenerative diseases (2022–2023). Dr. Leyva teaches courses in immunology and microbiology at Midwestern University, emphasizing translational research and medical education. Education: Ph.D. in Microbiology (Northern Arizona University, 1996), M.S. (University of Oregon, 1992), and B.S. (University of Oregon, 1990). Non-academic experience includes an ecology internship at The Nature Conservancy (1991). Research highlights include establishing a clinic-based biorepository, examining miRNA roles in EMT-driven oncogenesis, and investigating progranulin’s role in cellular subtypes. Her publications span biomolecules, molecular oncology, and cell biology, with a focus on translational cancer and neurodegenerative disease mechanisms. Teaching responsibilities span immunology and microbiology across podiatric, veterinary, and pharmacy programs. She mentors students through research electives and collaborates with interdisciplinary teams on grant-funded projects. Labs/Teams: Her research lab focuses on epigenetic regulation and cellular subtypes, leveraging zebrafish models and patient-derived tissues. Collaborations include multi-institutional studies on cancer biology and immunology.

• Food Engineering
• Food Science
• Food Technology
• +۴ مورد دیگر

Prof. NEŞE YILMAZ TUNCEL serves as a Professor in the Department of Food Technology at Çanakkale Onsekiz Mart University's Faculty of Applied Sciences, where she has progressed from Research Assistant (2009) to her current position since 2024. Her academic journey includes a Doctorate in Food Engineering from Çanakkale Onsekiz Mart University (2008-2014), Postgraduate studies at the same institution (2006-2008), and an Undergraduate degree from Trakya University (2002-2006), complemented by a Postdoctorate at ETH Zurich's Laboratory of Food Biochemistry (2014-2015). Her educational background demonstrates a deep commitment to food science: Postdoctorate: ETH Zurich, Switzerland (2014-2015) Doctorate: Çanakkale Onsekiz Mart University (2008-2014) Postgraduate: Çanakkale Onsekiz Mart University (2006-2008) Undergraduate: Trakya University (2002-2006) Prof. Yılmaz Tuncel's research focuses on sustainable food systems with emphasis on plant-based alternatives, cereal technology, and food by-product valorization. Her work explores germination effects on pulses, infrared stabilization of rice bran, development of pulse-based milk analogs, and reduction of antinutritional factors in plant foods. She integrates food engineering principles with nutritional science to address global food security challenges through innovative processing techniques. Analysis of her recent publications (2018-2025) reveals three dominant research trajectories: (1) Sustainable utilization of rice by-products through infrared stabilization, (2) Development of nutrient-dense plant-based beverages from pulses and alternative crops, and (3) Comprehensive investigation of antinutrient management in plant foods. Her work consistently bridges fundamental food chemistry with practical applications in food product development. Her scientific contributions have been recognized through prestigious awards: AKADEMİK TEŞVİK 100 TAM PUAN ÖDÜLÜ (2015) from Çanakkale Onsekiz Mart University Food and Bioproducts Processing IChemE Journals Best Reviewer Award 2015 BEST POSTER AWARD at ICC Bosphorus 2008 Prof. Yılmaz Tuncel has secured substantial research funding, primarily through TUBITAK projects (8 grants) and Higher Education Institutions (7 grants), focusing on rice processing, plant-based food development, and food safety. She serves in critical academic leadership roles including Head of the Department Bologna Commission, Erasmus Program Department Coordinator, and Mevlana Exchange Program Coordinator, demonstrating commitment to international academic collaboration and curriculum development. Her active participation in international research networks is evidenced by mobility activities at VTT Technical Research Centre of Finland, DTU Denmark, and University of Ljubljana, Slovenia, where she advances competencies in sustainable food technologies and contributes to European food science initiatives.

• Quantitative Decision Science
• Hematology-Oncology
• Health Economics
• +۳ مورد دیگر

Satoko Ito, MD, PhD, is a Postdoctoral Research Fellow at Yale School of Medicine (YSM) within the Department of Medical Oncology and Hematology. She serves as the Decision Analytic Modeling Research Lead in the Goshua Lab, the first U.S. laboratory specializing in hematology-oncology decision analytic modeling. Dr. Ito holds dual training as a hematologist and palliative care physician with over a decade of clinical practice. She earned her PhD in Epidemiology from Kyoto University (2021) and her MD from Okayama University (2005). Education: PhD in Epidemiology, Kyoto University (2021) MD in Medicine, Okayama University (2005) Research Interests: Dr. Ito focuses on quantitative decision science, particularly cost-effectiveness analyses and predictive modeling in hematology-oncology. Her work addresses treatment optimization for conditions like sickle cell disease, hemophilia, paroxysmal nocturnal hemoglobinuria, and iron deficiency anemia. She emphasizes translational research to bridge clinical evidence and healthcare policy. Publications: Recent work highlights her expertise in evaluating curative therapies, diagnostic algorithms, and equity-focused interventions. Key themes include cost-effectiveness of gene therapy vs transplant in sickle cell disease and optimizing diagnostic thresholds to reduce unnecessary testing. Collaborations: Active collaborators include Prof. George Goshua (Goshua Lab director), Harlan Krumholz, and Ayesha Butt, with frequent co-authorship on hematology economics topics. Labs/Teams: Leads decision modeling efforts in the Goshua Lab, advancing evidence-based practices in hematologic malignancies and blood disorders through interdisciplinary teams.

• Hepatology
• Inflammation Biology
• Molecular Pathology
• +۳ مورد دیگر

Arumugam Suyavaran is an Associate Research Scientist at Yale School of Medicine, affiliated with the Department of Digestive Diseases and Internal Medicine. His research focuses on inflammatory mechanisms in liver diseases, including hepatic ischemia-reperfusion injury, NLRP3 inflammasome activation, and mitochondrial dysfunction in fibrogenesis. He holds a PhD in Biochemistry and Molecular Biology from Pondicherry University (2017) and an MSc in the same field (2009). Key research interests include the role of mitochondrial DNA and STING pathway in hepatic stellate cell activation, as well as the anti-inflammatory effects of compounds like digoxin and fermented soy beverages (Q-CAN® Plus). He has been recognized with awards such as the AGA GRG Basic Science Trainee Award (2023) and a Presidential poster distinction (2023). His work integrates molecular biology, immunology, and computational approaches to study metabolic disorders (e.g., NAFLD, obesity) and alcoholic hepatitis. Collaborations include studies on multi-omics drug repositioning for NASH and proteomic biomarker identification in alcohol-associated hepatitis.

• Nephrology
• Kidney Disease
• Immunology
• +۳ مورد دیگر

Howard Zhang is an Assistant Clinical Professor of Internal Medicine at Yale School of Medicine, specializing in nephrology and clinical research. His work focuses on IgA nephropathy mechanisms, complement pathway inhibition, and gut-kidney crosstalk. He contributes to Phase 3 clinical trials such as the VISIONARY trial evaluating sibeprenlimab, and the ALIGN trial studying atrasentan. Zhang has published extensively in high-impact journals like NEJM and Kidney International, with research emphasizing biomarker discovery, drug efficacy, and renal disease progression. His recent work includes analysis of Nefecon efficacy in Chinese patients and long-term safety studies. Collaborations involve global clinical networks and translational research initiatives. Education details are not explicitly listed, but his academic role implies advanced training in medicine and nephrology. Research interests are anchored in clinical nephrology with a focus on translational studies bridging basic science and patient care. His publications reflect expertise in immunology, pharmacology, and clinical trial design. Grants and awards are not detailed in the text, though his active involvement in multiple Phase 3 trials suggests grant-funded research. Advising roles or mentorship activities are not specified here.

• Immunology
• Hematology
• Transfusion Medicine
• +۳ مورد دیگر

Edward Lee is an Instructor in Laboratory Medicine at Yale School of Medicine, with appointments in Clinical Fellow roles in Laboratory Medicine. His research focuses on immunohematology, blood group systems, and the application of advanced diagnostics like flow cytometry and machine learning in clinical settings. He is affiliated with the Kleinstein Lab, emphasizing translational research in hematology and transfusion medicine. Education: MD from Albert Einstein College of Medicine (2020), PhD in Immunology from University of Glasgow (2018), BA in Biology from The College of New Jersey (2012). Research interests include antibody responses to vaccines, hemolytic disorders, and improving diagnostic accuracy in blood group testing. His work addresses challenges in transfusion safety, rare blood antigen management, and clinical applications of automation in hematology. Recent studies explore SARS-CoV-2 antibody dynamics and the impact of storage conditions on blood products. Publications span topics like therapeutic plasma exchange outcomes, RhD antigen variability, and AI-driven analysis of clinical data. His work bridges basic science and clinical practice, with a focus on advancing diagnostic precision and patient care in hematology. No scientific awards are listed. Edward Lee has no recorded advisees or grant leadership positions highlighted in the provided data. He collaborates with the Kleinstein Lab on projects involving T cell dynamics and computational biology.

• Neuroscience
• Psychiatry
• Schizophrenia
• +۳ مورد دیگر

Professor Markus Leweke is Chair in Youth Depression Studies at the University of Sydney's Brain and Mind Centre, part of the Central Clinical School. He holds a dual affiliation with the Charles Perkins Centre and the Centre for Drug Discovery Innovation. Previously, he served as a full professor and associate medical director at Heidelberg University's Central Institute of Mental Health. His research focuses on translational neuroscience investigating the endocannabinoid system's role in severe mental illnesses like schizophrenia and bipolar disorder, employing clinical trials and animal models. Key areas include cannabinoid-based therapies, neuromodulation, and biomarker development for early intervention in youth mental health. Education: MD from the University of Cologne and additional training at UNSW Sydney. Clinical expertise spans neurology, psychiatry, and psychotherapy with specialization in addiction disorders and neuropsychopharmacology. Research interests emphasize cannabinoid pharmacology, psychiatric neurochemistry, and molecular imaging to uncover mechanisms for novel treatments. His work bridges basic science to clinical applications, including protocols like the Youth Mental Health Tracker longitudinal cohort study. Publications span over 20 years, focusing on endocannabinoid signaling, cannabidiol's therapeutic potential, and schizophrenia pathophysiology. Current projects include clinical trials evaluating cannabidiol's cognitive benefits and biomarker-driven personalized psychiatry approaches.

Mary Webberleyمشاهده پروفایل

عضو هیئت علمی

• Gastroenterology
• Medical Diagnostics
• Machine Learning in Healthcare
• +۳ مورد دیگر

Mary Webberley is an Adjunct Research Fellow at the School of Biomedical Sciences, University of Western Australia (UWA), based in the Marshall Centre. Her role complements her work at a UWA spin-out company, focusing on developing innovative diagnostic tools for gastrointestinal disorders. She holds a Natural Sciences undergraduate degree and a PhD from the University of Cambridge, followed by post-doctoral research in insect parasite ecology before transitioning to clinical research and commercialization. University Affiliation: The University of Western Australia Key Responsibilities: Project management for the Noisy Guts Project and clinical research in gastroenterology Her primary research interests include non-invasive diagnostics for irritable bowel syndrome (IBS), leveraging acoustic signal processing and machine learning. She is leading the development of an acoustic belt to monitor gut sounds, aiming to revolutionize screening and monitoring of gut disorders. Key research contributions span Helicobacter pylori epidemiology, bowel sound analysis methodologies, and the impact of gastrointestinal pathogens on microbiota. Her work intersects with UN Sustainable Development Goals related to health and innovation. Education: PhD in Natural Sciences (Cambridge), Postdoctoral Research in Insect Parasitology Awards include the 2018 WA IOTY Emerging Innovation Award (team) and the 2018 Breakout Female Scientist Award (individual). She actively engages in public outreach, including lectures on medical innovation.

• Molecular Pharmacology
• Respiratory System
• Cell Biology
• +۸ مورد دیگر

Dr. Hoeke Baarsma is a Lecturer in the Department of Pharmacy at the University of Groningen's Faculty of Science and Engineering. His research focuses on Molecular Pharmacology with an emphasis on respiratory system mechanisms, chronic diseases, and aging. He investigates the role of Wnt signaling pathways in lung physiology and pathology, particularly in conditions like COPD and idiopathic pulmonary fibrosis. His work also explores the effects of air pollutants and inflammatory responses in pulmonary systems. Baarsma has contributed to studies on drug repurposing (e.g., amlexanox) and in vitro models (e.g., 3D spheroids) for lung pathology research. He is actively involved in educational committees and program leadership in Pharmacy and Pharmaceutical Science. Research Interests: Molecular Pharmacology, Respiratory System Biology, Wnt Signaling Pathways, Chronic Lung Diseases, Air Pollution Effects, and Drug Development. His publications span over 36 peer-reviewed articles, focusing on mechanisms of lung inflammation, fibrosis, and regeneration. Baarsma holds ancillary roles as owner of H.A.Baarsma Beheer BV, complementing his academic activities.

Angela Creeمشاهده پروفایل

پژوهشگر

• Molecular Biology
• Ophthalmic Genetics
• Age-Related Macular Degeneration (AMD)
• +۳ مورد دیگر

Angela Cree is a Senior Research Manager in Vision Sciences within Clinical Neurosciences at the University of Southampton, based at University Hospital Southampton. She holds a BSc in Biochemistry from the University of Sheffield (1988) and an MSc in Genomic Medicine from the University of Southampton (2018). Her research focuses on molecular analysis of degenerative eye diseases, including age-related macular degeneration (AMD), primary open-angle glaucoma (POAG), and rod-cone degeneration. She leads the Vision Sciences research team’s integrated laboratory and clinical ophthalmic research program under Professor Andrew Lotery. Education: BSc Biochemistry, University of Sheffield (1988) MSc Genomic Medicine, University of Southampton (2018) Research Themes: Molecular Biology of Ophthalmic Genetics AMD and Glaucoma Pathogenesis Deep Phenotyping and Machine Learning in Ophthalmology Her work spans clinical trials (e.g., PINNACLE and VICI trials) and collaborative projects with institutions like the NIHR/Wellcome Trust Clinical Research Facility. She coordinates national research networks, including the UK NIHR Clinical Research Network, and contributes to international consortia like the International AMD Genetics Consortium (IAMDGC). Current funding partners include the National Institute for Health and Care Research (NIHR) and the Wellcome Trust. Angela has supervised numerous students, including PhD candidates and clinical fellows, and actively participates in academic governance roles such as the Clinical Neurosciences Board and the Gift of Sight charity.

Russell Diefenbachمشاهده پروفایل

پژوهشگر ارشد

• Virology
• Oncology
• Molecular Biology
• +۴ مورد دیگر

Russell Diefenbach is a Senior Research Fellow at Macquarie University's Macquarie Medical School and an Honorary Principal Research Fellow at the University of Sydney. His career spans postdoctoral research at the University of Toronto (1991–1994) and roles at the University of Sydney (1995) and the Westmead Institute for Medical Research (1996–2017). He holds a PhD in Biochemistry (University of Queensland, 1992) and a BSc(Hons) in Biochemistry (University of Queensland, 1987). Research Interests : Oncolytic virotherapy and viral entry mechanisms (HSV-1, HIV) Melanoma research, including liquid biopsies and circulating tumor DNA (ctDNA) analysis Clinical applications of ctDNA dynamics in cancer prognosis and treatment response MicroRNA biomarkers for melanoma prognosis Exosome-based biomarkers in melanoma Key Projects : "Multimodal Precision Liquid Biopsy to Predict Risk of Melanoma Recurrence" (2022–2025) "Exosomes: predictive and prognostic biomarkers in melanoma" (2018–2019) Recent Research Trends : His articles emphasize ctDNA analysis for melanoma recurrence prediction, immunotherapy response monitoring, and functional biomarker discovery. Work spans virology (HSV-1 assembly mechanisms) and molecular oncology (melanoma genomics). Awards : No awards explicitly mentioned in the texts. Advising & Grants : Led projects on liquid biopsy development and exosome biomarkers Collaborated on clinical trials for glioblastoma immunotherapy Labs/Teams : Affiliated with the Macquarie Medical School and the Westmead Institute for Medical Research, focusing on translational cancer research and virology.

Nicholas Coleمشاهده پروفایل

استاد مدعو

• Neurodegenerative Diseases
• Amyotrophic Lateral Sclerosis (ALS)
• Zebrafish Models
• +۴ مورد دیگر

Nicholas Cole is an Adjunct Professor at Macquarie University's Macquarie Medical School, affiliated with the Motor Neuron Disease Research Centre. His research focuses on neurodegenerative diseases, particularly amyotrophic lateral sclerosis (ALS) and motor neuron disorders, using zebrafish as a primary model system. Key projects include investigating protein aggregation in ALS, drug development for spinocerebellar ataxia, and understanding the molecular origins of frontotemporal dementia and ALS. Dr. Cole's work spans cellular pathology, genetic modeling, and neuroprotective strategies. Notable contributions include in vivo validation of biomolecular techniques, elucidating roles of FUS/TDP-43 proteins in ALS, and developing zebrafish models for muscular dystrophies. His research integrates molecular biology, neuroimaging, and genetic engineering to uncover disease mechanisms and potential therapies. He leads or collaborates on multiple active projects, including a laser platform for single-cell experiments in zebrafish and testing drugs for Machado-Joseph disease. His publications highlight advancements in understanding intracellular trafficking disruptions and sirtuin pathway modulation.