جست‌وجوی استاد و پژوهشگر

Ferran Casals Lópezمشاهده پروفایل

دانشیار

• Human Molecular Genetics
• Primary Immunodeficiencies
• Genetic Mosaicisms
• +۳ مورد دیگر

Ferran Casals López is an Associate Professor at the Department of Genetics, Microbiology and Statistics in the Faculty of Biology at the Autonomous University of Barcelona. His research focuses on understanding genetic mechanisms underlying primary immunodeficiencies, genetic mosaicisms, and alternative inheritance models in rare disorders. He coordinates master's programs in Genetics and Genomics and Bioinformatics, and teaches courses on molecular genetics and disease genetics. His research projects include studying somatic and germline mutations in immunodeficiencies, genetic modifying factors in periodic fevers, and medical genomics of common variable immunodeficiency (IDCV). He has led multiple projects funded by institutions like the Ministry of Science and Innovation and the European Union. Recent work involves nanopore sequencing applications and genomic analysis of human migration patterns. Casals has published extensively on topics including genetic load in primates, exome sequencing applications, and population genetics of Indian and Andamanese populations. His educational contributions include developing digital skills programs for health professionals in computational biology.

• Evolutionary Biology
• Genomics
• Ecology
• +۴ مورد دیگر

Matthew Brachmann is a Researcher at the University of Glasgow, specializing in evolutionary mechanisms and genomic studies of aquatic species. His work focuses on adaptive divergence, ecological genomics, and conservation genetics of fish such as Arctic charr, lumpfish, and Atlantic salmon. He investigates how environmental factors and genomic processes drive phenotypic and ecological divergence in populations. Brachmann's research employs advanced genomic techniques, including whole-genome sequencing and SNP array development, to study population structure and introgression risks in aquaculture settings. He has contributed to understanding sex determination pathways in lumpfish through reference genome analysis and applied machine learning for conservation genetics. His collaborative projects include studies on spatial genetic structure in Northwest Atlantic lumpfish, parallel evolution in Icelandic Arctic charr morphs, and chromosomal rearrangements in intertidal snails. While no formal student advisees are listed, his work represents significant contributions to evolutionary biology and conservation science. Brachmann's publications span high-impact journals like Molecular Ecology and Ecology and Evolution, reflecting his expertise in ecological genomics and evolutionary processes.

Chelsea Spechtمشاهده پروفایل

استاد

• Plant Diversity
• Comparative Genomics
• Evolutionary Biology
• +۵ مورد دیگر

Chelsea Specht is the Barbara McClintock Professor of Plant Biology at Cornell University, affiliated with the School of Integrative Plant Science’s Plant Biology Section and the L.H. Bailey Hortorium. She holds roles as Associate Dean of Faculty and Associate Director for Faculty Development, Equity, and Inclusion. Her research focuses on plant diversity, evolutionary biology, and the integration of morphological, genomic, and phylogenetic approaches to study plant form and function. She has mentored 5 graduate students and 4 postdocs, with grants from the NSF since 2006, including an NSF CAREER award. Awards include the Grady Webster Award (2016) and fellowships from the California Academy of Sciences and National Academy of Sciences. Education: B.A. (Biology/Psychology) from University of Delaware (1993), M.S. (Biology) and Ph.D. (Biology) from New York University (1997, 2004). Research interests span plant systematics, biogeography, and developmental genetics. Current projects include studies on Zingiberales floral evolution, Calochortus speciation, and the development of comparative analysis tools like ArborWorkflows. She is active in promoting diversity and inclusion in academia, serving as President of the American Society of Plant Taxonomists and Director for Diversity, Equity, and Inclusion at the Botanical Society of America. Labs/Teams: Specht Lab (focusing on plant biodiversity and inclusive mentoring), L.H. Bailey Hortorium, and collaborations with institutions like the Atkinson Center for a Sustainable Future.

Ivan Hucمشاهده پروفایل

استاد

• Foldamer Design
• Synthetic Methodologies
• Molecular Motors
• +۳ مورد دیگر

Professor Ivan Huc leads the Ivan Huc Group at the Department of Pharmacy, Ludwig-Maximilians-University of Munich (since 2017), affiliated with the Center for Integrated Protein Science. His research focuses on designing synthetic folded molecular architectures (foldamers) inspired by biopolymers but offering novel structural and functional capabilities. Key projects include molecular motor development, protein surface recognition applications, and electron transport for materials science. He collaborates with x-ray crystallography experts and maintains ties with the CBMN Laboratory in Bordeaux. Research highlights include an eight-helix bundle paper featured in Chemistry World and Angewandte Chemie publications. Collaborations involve Dr. G. Guichard and Dr. Y. Ferrand on foldamer studies. His work bridges organic chemistry with interdisciplinary applications in materials and biological systems through dynamic covalent chemistry approaches.

Simon Jolyمشاهده پروفایل

دانشیار

• Plant Evolution
• Biodiversity
• Phylogenetics
• +۴ مورد دیگر

Simon Joly is an Associate Professor at the Université de Montréal, affiliated with the Faculty of Arts and Sciences and the Department of Biological Sciences. He leads the Institut de recherche en biologie végétale and specializes in plant evolution, combining molecular biology, phylogenetics, and ecological studies. His research focuses on floral evolution, speciation, and biodiversity conservation. He holds a Ph.D. in Biology from Université de Montréal (2006). Education: Ph.D. in Biology, Université de Montréal (2006) Research Interests: His work explores plant evolution through genomic and ecological lenses, including studies on pollination systems, hybridization, and urban environmental impacts. Key topics include floral adaptation, phylogenetic analysis, and conservation strategies for threatened species. Grants & Projects: Evolution of flowers in urban environments (2024–2030), funded by the Natural Sciences and Engineering Research Council of Canada (NSERC). Leading the Centre de la science de la biodiversité du Québec (2013–2020), supported by Fonds de recherche du Québec. Multiple studies on Gesneriaceae species and phylogenetic methods, funded by NSERC and international collaborations. Labs & Teams: Directs the Plant Evolution Lab at the Montreal Botanical Garden, emphasizing interdisciplinary research in plant genetics and ecology.

• Cell Division Mechanisms
• Microtubule Dynamics
• Cancer Therapeutics
• +۳ مورد دیگر

Benjamin Heibun Kwok is a Professor in Medical Sciences at Université de Montréal, affiliated with the IRIC (Institut de recherche en immunologie et en cancérologie) and the Oncopole. His research focuses on molecular mechanisms of cytoskeleton dynamics and cell division, particularly the role of kinesin motor proteins in mitotic spindle assembly. He employs interdisciplinary approaches combining biochemistry, cell biology, and high-resolution microscopy to study spindle formation in vertebrate cell cultures and in vitro systems. Education: PhD in Biochemistry from Yale University (2002), postdoctoral training at Rockefeller University (2002-2008). Research emphasizes cancer therapy through targeting mitotic spindle components, including development of small-molecule tools for biomedical research and chemotherapy. Grants: Over 10 funded projects from NIH, Canadian institutes, and Quebec funding bodies (2009–present) Led projects on kinesin-13 modulation, microtubule dynamics, and DNA repair Supervised 2 graduate students (PhD and MSc theses completed in 2021/2023). Active in lab establishment at IRIC since 2010, focusing on translating molecular discoveries into clinical applications.

Courtney Schroederمشاهده پروفایل

استادیار

• Evolutionary Biology
• Cytoskeletal Biology
• Germline Biology
• +۵ مورد دیگر

Dr. Courtney Schroeder is an Assistant Professor in the Department of Pharmacology at UT Southwestern Medical Center, where she established her independent research group in November 2021. She leads investigations into cytoskeletal evolution using interdisciplinary approaches including fly genetics, structural biology, and evolutionary analysis. Education: B.S. in Chemistry (Biochemistry specialization) - University of Virginia MPhil in Biochemistry - University of Cambridge (Churchill Scholar) Ph.D. - UC San Francisco (Ron Vale Lab) Postdoctoral Fellowship - Fred Hutchinson Cancer Research Center (Harmit Malik Lab) Her research explores rapidly evolving non-canonical cytoskeletal proteins and their roles in fertility, development, and cancer. Key focus areas include: Evolutionary diversification of cytoskeletal proteins in germline biology Functional consequences in Drosophila and mammalian systems Structural analysis of divergent actin-related proteins (Arps) Roles in cancer progression and reproductive health She employs techniques ranging from evolutionary genomics to high-resolution imaging. Her recent publications (2018-2023) demonstrate strong focus on cytoskeletal diversification mechanisms, particularly through studies of actin-related proteins in Drosophila testis function, ciliary assembly, and dynein motor mechanisms. Work consistently integrates evolutionary biology with cellular mechanistics. Awards & Honors: Churchill Scholarship She actively recruits PhD students, postdoctoral fellows, and technicians for her lab, focusing on cytoskeletal evolution research. Current projects investigate: Divergent cytoskeletal proteins in cancer Testis-specific Arps in female fertility High-resolution analysis of sperm maturation mechanisms

Ram Maniمشاهده پروفایل

دانشیار

• Cancer Biology
• Molecular Genetics
• Epigenetics
• +۴ مورد دیگر

Ram Mani, Ph.D., is an Associate Professor in the Departments of Pathology and Urology at the University of Texas Southwestern Medical Center. He leads the Mani Lab, focused on understanding molecular and epigenetic mechanisms driving cancer development, with translational goals in diagnostics and therapeutics. His research integrates genomic, bioinformatic, and experimental approaches to study DNA damage pathways and transcriptional dysregulation in cancer. Dr. Mani holds prestigious awards, including the NIH K99/R00 Pathway to Independence Award and the Prostate Cancer Foundation's Young Investigator Award. Education: Ph.D. in Human Molecular Genetics, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore Postdoctoral Training: Prostate Cancer Genomics & Epigenetics under Prof. Arul Chinnaiyan, University of Michigan Research Focus: Investigates genomic rearrangements, DNA repair pathways, and epigenetic regulation in cancers like prostate and breast. Key areas include therapeutic resistance mechanisms, 3D genome organization, and tumor heterogeneity. Awards: NIH K99/R00 Pathway to Independence Award Young Investigator Award (Prostate Cancer Foundation) Lab & Collaborations: The Mani Lab, located on the 7th floor of the NB building, employs interdisciplinary teams to advance cancer research. Collaborations include the Harold C. Simmons Comprehensive Cancer Center and global institutions.

Steve Julioمشاهده پروفایل

استاد

• Infectious Disease
• Microbiology
• Bacterial Pathogenesis
• +۳ مورد دیگر

Steve Julio is a Professor of Biology at Westmont College, specializing in the mechanisms of infectious diseases with a focus on Bordetella pathogenesis. He earned his doctorate from UC Santa Barbara and has conducted research on bacterial pathogenesis, including work at a cancer vaccine-focused startup. His research explores how Bordetella bacteria colonize respiratory tracts and modulate host immunity, particularly investigating strain-specific host preferences. He returned to Westmont in 2006 and continues his interdisciplinary research combining genetics, biochemistry, and animal models. Education: B.A. from Westmont College, Ph.D. in Biology from UC Santa Barbara. His work bridges fundamental microbiology with applied research on bacterial virulence factors and host-pathogen interactions. Research Interests: Bordetella pathogenesis, mechanisms of host specificity, bacterial colonization strategies, respiratory tract infections, and bacterial immunomodulation. His studies aim to uncover how pathogens adapt to different host environments and evade immune responses. Publications highlight his focus on Bordetella virulence factors (e.g., PlrSR regulatory systems, filamentous hemagglutinin), host adaptation, and comparative analyses of bacterial strains. Earlier work includes studies on Yersinia and Salmonella pathogenesis. No scientific awards are explicitly listed. Advising and grant details are not provided in the text. His lab focuses on understanding bacterial pathogenesis with potential implications for vaccine development and infection control strategies.

Jaakko Pohjoismäkiمشاهده پروفایل

استاد

• Molecular Biology
• Genetics
• Mitochondrial Biology
• +۵ مورد دیگر

Jaakko Pohjoismäki is a Professor of Molecular Biology and Molecular Genetics at the University of Eastern Finland, affiliated with the Department of Environmental and Biological Sciences within the Faculty of Science, Forestry and Technology. His research focuses on mitochondrial biology, genetics, and biodiversity, with a particular emphasis on applying biomedical methods to study species diversity. He earned his Master’s degree from the former University of Joensuu and his PhD in Molecular Biology from the University of Tampere, followed by postdoctoral work at the Max Planck Institute for Heart and Lung Research in Germany. His key research interests include mitochondrial DNA maintenance, evolutionary biology, and the application of genomic tools to biodiversity studies. He leads research groups on Hare Research, Mitochondrial Biology, and Entomology. Notable achievements include compiling high-quality reference genomes for Finnish hares and advancing DNA sequencing methods for species inventory. He also holds a Docent title in Molecular Genetics from the University of Eastern Finland (2013). Pohjoismäki’s work bridges basic molecular mechanisms with ecological questions, such as understanding speciation through hybridization studies of hares and leveraging genomics to address biodiversity loss. His research integrates computational methods for large-scale data analysis, reflecting the rapid advancements in biological fields. He actively contributes to education, emphasizing the growing gap between secondary education and cutting-edge research skills. His laboratory focuses on interdisciplinary approaches, combining molecular techniques with ecological studies. Collaborations include projects like the European Reference Genome Atlas (ERGA) for species genomics. Beyond academia, he maintains strong ties to nature through hobbies like Finnish Spitz breeding and traditional hunting cultures, which inform his research perspectives.

Zheng Liمشاهده پروفایل

استادیار

• Genome Evolution
• Phenotypic Evolution
• Biodiversity
• +۵ مورد دیگر

Zheng Li is an Assistant Professor and Herbarium Director in the Department of Biology at Miami University. Their research focuses on eukaryotic genome evolution, particularly how genomic changes drive phenotypic diversity in plants and insects. Key interests include gene and genome duplication, chromosomal evolution, and horizontal gene transfer. Education: Ph.D., Ecology and Evolutionary Biology, University of Arizona (2020) B.S., Botany and Zoology, Miami University (2013) Research explores evolutionary mechanisms such as duplicate gene retention, genome duplication dynamics across taxa, and genomic innovations. The Li Lab is located in Pearson Hall and collaborates with the Cellular, Molecular, and Structural Biology Graduate Program. Recent publications highlight genomic studies in aphids, leafhoppers, and conifers. Lab & Team: The Li Lab investigates biodiversity origins through genomic approaches, emphasizing plant and insect systems. Fieldwork and lab-based studies combine to address fundamental evolutionary questions.

Linda Vigilantمشاهده پروفایل

پژوهشگر

• Primate Evolution
• Genetic Analysis
• Mitochondrial DNA
• +۳ مورد دیگر

Linda Vigilant is a Group Leader at the Department of Primate Behavior and Evolution at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany. She has been a Research Scientist at the Max Planck Institute for Evolutionary Anthropology since January 1999, focusing on genetic analyses of wild primate populations across Africa. Dr. Vigilant earned her PhD in Genetics from the University of California, Berkeley (1986-1990) and completed her undergraduate studies in Chemical Biology at the same institution with High Honors (1982-1986). Prior to her position at the Max Planck Institute, she held research positions at Penn State University as a Postdoctoral Fellow (1990-1992) and Research Associate (1992-1994, 1997-1998). Her research focuses on using genetic analyses to address questions on the evolution of humans and other primates, particularly the great apes. She began her career working on the evolution of mitochondrial DNA in human populations. At the MPI-EVA, she has worked collaboratively with field researchers studying primate social behavior. Recently, she has become interested in using large-scale sequencing approaches for understanding the long-term histories of primate populations and seeing the effects of high variance in male reproductive success on patterns of genomic variation. Dr. Vigilant's extensive publication record demonstrates her expertise in primate genetics, population structure, and evolutionary biology. Her work spans chimpanzee and gorilla population dynamics, reproductive strategies, genetic adaptation, and social behavior across Africa. She has made significant contributions to understanding primate evolution through innovative genetic approaches applied to wild populations. She serves on the editorial boards of several prestigious journals, including as Review Editor for the American Journal of Primatology (2014-present), and previously served on the editorial boards of the International Journal of Primatology (2003-2015), American Journal of Physical Anthropology (2006-2010), Primates (2007-2017), and as Topical Editor for Primate Biology (2014-present).

• DNA Replication
• Cell Cycle Regulation
• Checkpoint Control
• +۶ مورد دیگر

Nicholas Rhind is a Professor at UMass Chan Medical School with appointments across multiple departments including Biochemistry and Molecular Biotechnology, Radiology Division Cellular Biology & Imaging, and several programs within the Morningside Graduate School of Biomedical Sciences. His research laboratory focuses on fundamental mechanisms of DNA replication and cell cycle regulation. Dr. Rhind received his academic training at Brown University where he earned both a B.S. in Mathematics and a B.A. in Biology. He completed his Ph.D. in Molecular & Cell Biology at the University of California, Berkeley in 1995, where he studied worm sex determination with Barbara Meyer. Following his doctoral work, he was a Leukemia and Lymphoma Society post-doctoral fellow with Paul Russell at the Scripps Research Institute from 1996 to 2001. Dr. Rhind's research primarily utilizes fission yeast ( Schizosaccharomyces pombe ) as a model system to investigate how DNA replication is regulated during S phase. His laboratory has made significant contributions to understanding replication timing patterns, demonstrating that the number of MCM complexes loaded at origins regulates when replication occurs. He has also extensively studied how cells respond to DNA damage during replication through the S-phase checkpoint, identifying pathways that coordinate replication and recombinational repair. His work bridges computational, genetic, and biochemical approaches to reveal fundamental mechanisms conserved from yeast to humans. Analysis of Dr. Rhind's recent publications reveals a continued focus on replication timing mechanisms, with increasing incorporation of computational modeling and genome-wide approaches. His 2022-2024 work has expanded into topological aspects of chromosome organization and refined models of replication fork dynamics, while maintaining his signature integration of mathematical frameworks with experimental biology. Dr. Rhind actively mentors graduate students through multiple programs at UMass Chan, including the Biochemistry and Molecular Biotechnology graduate program, the Biophysical Chemical and Computational Biology program, and the MD/PhD program. His laboratory offers rotation projects focused on replication-checkpoint coordination and regulation of replication timing. While specific grant information isn't detailed in the provided text, his extensive publication record spanning nearly three decades suggests sustained research funding. Dr. Rhind's laboratory maintains a strong focus on fission yeast as a model system, utilizing its simple cell cycle and genetic tractability to address fundamental questions in DNA replication. His work connects basic mechanisms to human health, as many cell cycle and checkpoint pathways first discovered in yeast are directly relevant to cancer biology and genome instability diseases.

• Aneuploidy
• Cancer Biology
• Cellular Metabolism
• +۴ مورد دیگر

Eduardo M. Torres is an Associate Professor at UMass Chan Medical School, affiliated with the T.H. Chan School of Medicine and the Morningside Graduate School of Biomedical Sciences. He holds positions in the Molecular, Cell and Cancer Biology Department, the Program in Molecular Medicine, and interdisciplinary graduate programs. Dr. Torres earned a BS in Physics from City College of New York and a PhD in Physiology & Biophysics from Weill Cornell Graduate School of Medical Sciences. His research focuses on aneuploidy’s impact on cellular physiology, metabolism, and cancer development. Using Saccharomyces cerevisiae as a model, his lab investigates how aneuploidy alters proliferation, metabolism, and genomic stability. Key findings include aneuploidy’s role in promoting metabolic liabilities (e.g., sphingolipid synthesis) and its evolutionary adaptations in cancer cells. Recent publications emphasize metabolic consequences of aneuploidy, including sphingolipid detoxification pathways and fitness improvements via gene mutations. His work highlights potential avenues for anti-cancer therapies targeting aneuploidy-associated vulnerabilities. Dr. Torres oversees postdoctoral and graduate training programs, emphasizing collaborative research in cancer biology and cellular metabolism. His lab actively recruits motivated candidates with expertise in genetics, biochemistry, or cell biology.

• RNA Silencing Pathways
• Gene Regulation
• RNA Interference (RNAi)
• +۵ مورد دیگر

Phillip D. Zamore is the Gretchen Stone Cook Chair of Biomedical Sciences and Professor of Biochemistry and Molecular Pharmacology at the University of Massachusetts Chan Medical School. He chairs the RNA Therapeutics Institute, established in 2009, and is an Investigator at the Howard Hughes Medical Institute. His research focuses on small RNA silencing pathways, including RNA interference (RNAi), microRNA, and PIWI-interacting RNA (piRNA) mechanisms, with applications in developing therapies for diseases like Huntington’s. He holds a Ph.D. in Biochemistry and Molecular Biology from Harvard University and completed postdoctoral research at MIT and the Whitehead Institute. **Education**: AB in Biochemistry & Molecular Biology, Harvard University (Cambridge, MA) PhD in Biochemistry & Molecular Biology, Harvard University **Research Interests**: Zamore’s lab explores how small RNAs regulate gene expression and repress transposons in eukaryotes and prokaryotes. Key areas include the molecular mechanisms of RNAi, piRNA-mediated silencing, and translational control during embryogenesis. His work bridges fundamental biology with translational medicine, aiming to design therapies for genetic disorders. **Publications & Impact**: With over 125 publications, Zamore is among the most cited researchers in his field. His lab’s discoveries underpin technologies like Alnylam Pharmaceuticals’ RNAi-based drugs and Voyager Therapeutics’ platforms. Recent work highlights piRNA biogenesis, transposon defense, and CRISPR-Cas9 optimization for precise genome editing. **Awards & Affiliations**: Recognitions include the Chancellor’s Medal for Excellence in Scholarship (2015) and election to the National Academy of Inventors (2014). He co-founded Alnylam and Voyager Therapeutics, serving on their scientific advisory boards. His lab collaborates globally, advancing RNA-based therapies and mechanistic insights into post-transcriptional gene regulation. **Labs & Collaborations**: The Zamore Lab is part of the RNA Therapeutics Institute, a hub for interdisciplinary research in RNA biology. They use biochemical, genetic, and computational tools to dissect RNA pathways. Active projects include understanding PUMILIO/NANOS-mediated mRNA regulation in Drosophila embryos and developing CRISPR-based editing strategies using microRNA scaffolds.