جست‌وجوی استاد و پژوهشگر

Xuming Zhangمشاهده پروفایل

استاد

• Molecular Biology
• Virology
• Coronavirus Pathogenesis
• +۵ مورد دیگر

Xuming Zhang is a Professor in the Department of Microbiology and Immunology at the University of Arkansas for Medical Sciences (UAMS) College of Medicine. He holds a Ph.D. from Justus-Liebig University of Giessen, Germany, with postdoctoral training at Louisiana State University and the University of Southern California School of Medicine. His research focuses on understanding molecular mechanisms of coronavirus pathogenesis, particularly using murine coronavirus (MHV) as a model to study multiple sclerosis and neurodegenerative diseases. Key interests include viral RNA persistence in central nervous system (CNS) cells, viral-induced apoptosis in oligodendrocytes, and regulation of viral RNA synthesis through cellular signaling pathways such as MEK/ERK. His lab also explores antiviral drug discovery and development of viral vectors for vaccine applications. Recent work highlights studies on resveratrol's antiviral effects via sirtuins, identification of anti-coronavirus compounds, and analysis of coronavirus stability on food surfaces. His research bridges molecular virology, neuroimmunology, and host-pathogen interactions, with implications for developing therapies against viral CNS infections. Dr. Zhang's laboratory investigates cellular gene regulation during coronavirus infection, including over 200 differentially expressed genes identified via microarray analysis. Current efforts focus on mechanisms linking viral persistence to oligodendrocyte dysfunction and the role of transcription factors like Egr-1 in viral replication.

Margherita Bertuzziمشاهده پروفایل

مدرس

• Molecular Microbiology
• Fungal Pathogenesis
• Host-Pathogen Interactions
• +۳ مورد دیگر

Dr. Margherita Bertuzzi is a Lecturer in Molecular Microbiology at the University of Manchester, affiliated with the Division of Evolution, Infection and Genomics and the Manchester Fungal Infection Group (MFIG). She holds roles as Co-Director of the MSc Infection Biology program and PGT Unit Lead for Host-Pathogen Interaction lectures and Research Project II. Her research focuses on fungal infection biology, particularly the antifungal phagocytic activities of respiratory epithelia in health and disease, with emphasis on pH-mediated signaling and COPD-related dysfunctions. She leads a team employing single-cell technologies and immunological analyses to study fungal-epithelial interactions. Education: BSc (Hons) Molecular Biology, University of Padua, Italy (2002-2005) MRes Human Health Biology, University of Padua, Italy (2005-2007) PhD Molecular Mycology, Imperial College London, UK (2007-2011) Research Interests: Her work explores epithelial encounters with respiratory pathogens, immune response modulation, and translational applications. Key areas include Aspergillus fumigatus pathogenesis, COPD exacerbations, and host-microbe interactions using cutting-edge imaging and single-cell techniques. Awards: MRC Discovery award (2017) MRC New Investigator Research grant (2021) Teaching & Mentoring: She delivers lectures on molecular mycology, mentors PGT students, and oversees research projects. Recent supervisees include PhD candidates (e.g., Patrick Dancer) and MSc/MRes students (e.g., Anna Möslinger, Caitlin Sergienko). Labs & Collaborations: Collaborations with Manchester University NHS Foundation Trust and the National Aspergillosis Centre support clinical translation. Her lab integrates interdisciplinary approaches to address fungal infection challenges aligned with UN SDG 3 (Good Health).

Kate Staceyمشاهده پروفایل

استاد

• Innate Immunity
• Inflammasome Signaling
• Autoimmunity Mechanisms
• +۳ مورد دیگر

Professor Kate Stacey holds dual roles as Director of Research and Professor within the School of Chemistry and Molecular Biosciences at The University of Queensland, Faculty of Science. Her research focuses on innate immune cell activation by pathogen products, particularly mechanisms of DNA recognition and inflammasome signaling. She completed her PhD at UQ on macrophage transcriptional regulation and held a CJ Martin Fellowship at the University of Cambridge before returning to UQ in 1996. She was awarded an ARC Future Fellowship in 2009. Education: Bachelor (Honours) of Science (Advanced), The University of Queensland Doctor of Philosophy, The University of Queensland Her research interests include: - Recognition of foreign DNA via TLR9, AIM2, and cGAS pathways - Inflammasome-induced cell death mechanisms (caspase-1/pyroptosis and caspase-8 apoptosis) - Autoimmunity in lupus through dysregulated innate immune responses - Evolutionary conservation of DNA defense mechanisms across species Recent work highlights structural biology insights into TLR signaling complexes and inflammasome activation pathways, with implications for viral infections like dengue and SARS-CoV-2. Key findings include dual death pathways activated by inflammasomes and novel therapeutic approaches targeting TLR4 signaling. Awards: ARC Future Fellowship (2009), NHMRC Research Fellowship (2014–2019), multiple NHMRC Project Grants. Supervision: Active advisor for PhD students researching TLR signaling, dengue pathogenesis, and evolutionary immune mechanisms. Has supervised over 20 completed theses since 2003.

• Neuroscience
• Immunology
• Chronic Neuropathic Pain
• +۴ مورد دیگر

Associate Professor Paul Austin is affiliated with the School of Medical Sciences at the University of Sydney's Faculty of Medicine and Health. His research focuses on neuro-immune mechanisms underlying chronic neuropathic pain, particularly exploring inflammatory mediators and their roles in affective disabilities and motor deficits. He teaches neuroanatomy and neuroscience to medical and science students, specializing in basal ganglia anatomy and nociceptive pathways. Current research projects investigate neuroimmune interactions in chronic pain and neurodegeneration, using rodent models to study behavioral changes and immune activation in human conditions like Complex Regional Pain Syndrome (CRPS). His work integrates neuroanatomical, immunohistochemical, and imaging techniques. Grants: 2022: Machine learning-based disease models for spinal cord imaging 2021: CRPS immune-autonomic dysfunction analysis 2019: Photobiomodulation in Sanfilippo syndrome Students: Supervising Fred COLLIN, Dolores HUANG, and Jackson KARRASCH on neuroimmune mechanisms, CRPS imaging, and high-parameter cytometry. Labs: Focuses on neuroinflammation, pain biomarkers, and translational neuroimmunology.

Fabiola Aghakhani Zandjani-Martinمشاهده پروفایل

پژوهشگر ارشد

• HIV/AIDS Research
• HTLV-1 Pathogenesis
• Public Health Policy
• +۳ مورد دیگر

Dr. Fabiola Aghakhani Zandjani-Martin is an Honorary Senior Research Fellow at the University of Queensland's School of Public Health. Her research focuses on HTLV-1 (human T-lymphotropic virus type 1) pathogenesis, HIV/AIDS epidemiology, and public health policy. She leads and contributes to global studies on HTLV-1-associated myelopathy (HAM/TSP), cancer survival mechanisms linked to sodium channel-inhibiting drugs, and HIV care transitions. Key affiliations include collaborations with institutions in Australia, Japan, Brazil, and the UK. Her work spans clinical trials (e.g., the HAMLET-P corticosteroid trial for HAM/TSP) and systematic reviews, such as consensus guidelines for HAM/TSP management. She also investigates intersectional topics like HTLV-1 and SARS-CoV-2 interactions, and cancer therapeutics. Education : No explicitly stated degrees, but inferred expertise from publications in virology, immunology, and public health. Research Themes : HTLV-1 virology, HIV care outcomes, drug-cancer survival links, and neuroimmunological disorders. Grants/Projects : Involved in multi-country clinical trials and observational studies funded by global health initiatives. Her articles highlight contributions to HTLV-1 epidemiology (e.g., Queensland's adult leukemia/lymphoma study), HIV transition care (mortality analysis in young adults), and methodological advances in HTLV-1 detection.

Margot Elizabeth Quinlanمشاهده پروفایل

استاد

• Cell Biology
• Molecular Biology
• Actin Cytoskeleton
• +۴ مورد دیگر

Margot Elizabeth Quinlan is a Professor in the Department of Chemistry and Biochemistry at the University of California Los Angeles, where she leads a research program focused on cytoskeletal dynamics and cellular mechanics. Her work bridges molecular biology, biophysics, and cell biology, with particular emphasis on actin filament organization and formin proteins. Dr. Quinlan's educational background includes: Ph.D. in Cell and Molecular Biology from University of Pennsylvania (2002) B.A. in Biology from Reed College (1991) Her research interests center on cytoskeletal dynamics, particularly the role of formin proteins in actin polymerization and cellular organization. She has made significant contributions to understanding how formins regulate actin filament assembly in diverse cellular contexts including cardiomyocytes, neurons, and during bacterial infection. Her work employs sophisticated biochemical, biophysical, and cell biological approaches to dissect molecular mechanisms of cytoskeletal regulation. Analysis of her recent publications reveals a consistent focus on formin proteins and their diverse roles across biological systems. Her research spans fundamental mechanisms of actin dynamics, implications for cardiac function, neuronal development, and pathogen-host interactions. She has developed important insights into how formins interact with other cytoskeletal components and how their activity is regulated through post-translational modifications. Dr. Quinlan maintains an active research laboratory (Quinlan Lab) at UCLA, with publications spanning cell biology, microbiology, neuroscience, and developmental biology. Her work has established important connections between basic cytoskeletal mechanisms and physiological processes across multiple systems.

Nigel Hooperمشاهده پروفایل

استاد

• Neurodegenerative Diseases
• Alzheimer's Disease
• Prion Diseases
• +۳ مورد دیگر

Nigel Hooper is a Professor and Chair in Cell Biology at the University of Manchester's Division of Neuroscience within the Faculty of Medical and Human Sciences. He holds leadership roles as Associate Vice-President for Research and Strategic Lead of the Geoffrey Jefferson Brain Research Centre. Previously, he served as Director of Dementia Research (2015–2020) and Vice Dean for Research and Innovation (2016–2020). His research focuses on neurodegenerative diseases, particularly Alzheimer's and prion diseases, exploring proteolytic mechanisms and protein-membrane interactions. Education includes a B.Sc. (1984) and Ph.D. (1987) in Biochemistry from the University of Leeds. He held academic roles at the University of Leeds, including Professor of Biochemistry (2001–2014), before joining Manchester. Awards include Fellowship of the Royal Society of Biology (2016) and membership in Academia Europaea (2017). Key research interests include ACE/ACE2 biology, prion protein biology, and Alzheimer's amyloid-β production. Current projects investigate ACE2 activation in Alzheimer's, receptors for neuroprotective proteins, LDL receptor proteolysis, and 3D stem cell models of dementia. His work bridges biochemical and cellular techniques with animal models and human tissues. Over 96 publications span topics like tau proteolysis, neurovascular dysfunction, and protein catabolism. He advises journals such as Essays in Biochemistry and serves on the Biochemical Society’s Portland Press Board. Supervised 14 research students and led projects funded by MRC, Alzheimer’s Research UK, and other agencies.

Anne McBrideمشاهده پروفایل

دانشیار

• Microbiology
• Fungal Pathogenesis
• RNA-binding Proteins
• +۲ مورد دیگر

Anne McBride is Associate Professor of Biology and Biochemistry at Bowdoin College. Her research investigates Candida albicans, focusing on how RNA-binding proteins regulate the yeast-to-hyphal transition critical for fungal pathogenicity. She employs genetics, biochemistry, and microscopy techniques to study cellular mechanisms of infection. Education includes: PhD, University of Colorado-Boulder MPhil, University of Cambridge BS, Yale University Research explores microbial behavior, RNA-protein interactions, and host-pathogen dynamics. Current projects examine She3-interacting proteins and their roles in hyphal formation. No awards, student advising, or recent publications are detailed in the provided text.

• Medical Microbiology
• Antimicrobial Resistance
• Zoonotic Diseases
• +۳ مورد دیگر

Professor Mark Fielder is a Professor of Medical Microbiology at Kingston University, UK, affiliated with the Department of Biomolecular Sciences in the Faculty of Health, Science, Social Care and Education. He holds a PhD from King's College London (1995) and has been a faculty member since 1998, progressing to a professorship in 2011. His research focuses on rapid infectious disease diagnostics, antimicrobial resistance mitigation, and One Health approaches to zoonotic diseases. Education: BSc Microbiology (King's College London), PhD in Microbiology and Immunology (1995) Awards: Tadion-Rideal Prize for outstanding doctoral work Research Interests: Development of novel diagnostic tools, combating antimicrobial resistance in clinical/veterinary contexts, antibiotic overspill into wildlife populations, and zoonotic disease dynamics. Current projects include Nipah virus ecology in bat reservoirs and biofilm characterization in Mycoplasma species. Publications span 30 years, emphasizing antimicrobial strategies, zoonotic risk management, and diagnostic innovation. Recent work highlights One Health frameworks in China's wildlife trade and pandemic response mechanisms for SARS-CoV-2. Awards: Tadion-Rideal Prize (1995) Advisory Roles: Adviser to Clinical Laboratory Sciences Institute, Member of Parliamentary and Scientific Committee, and President of the Society for Applied Microbiology.

Akhil Vaidyaمشاهده پروفایل

استاد

• Molecular Parasitology
• Antimalarial Drug Development
• Mitochondrial Biology
• +۲ مورد دیگر

Akhil Vaidya, PhD, is a Professor in the Department of Microbiology & Immunology at Drexel University College of Medicine, where he also serves as Director of the Center for Molecular Parasitology. He obtained his PhD from the University of Bombay in 1972. His research focuses on understanding the molecular functioning of malaria parasites to develop new antimalarial drugs, with particular emphasis on mitochondrial biology and parasite metabolism. His laboratory investigates essential mitochondrial processes in Plasmodium parasites including electron transport chain function, ATP synthase assembly, and pyrimidine biosynthesis pathways. These studies have led to discoveries of novel drug targets and mechanisms of existing antimalarials like atovaquone/proguanil (Malarone). Dr. Vaidya collaborates internationally on drug discovery projects with Medicines for Malaria Venture, including development of pyrazoleamide compounds that disrupt parasite sodium homeostasis. Research publications demonstrate consistent focus on molecular parasitology, mitochondrial function in apicomplexans, antimalarial drug mechanisms, and parasite metabolism. Recent work explores mitochondrial ribosomal proteins, metabolic roles of endosymbiotic organelles, and transcriptional regulation in Plasmodium. Honors & Awards: Provost Award for Outstanding Scholarly Productivity - Career (2024) Award for Excellence in Basic Science Mentoring (2023) He leads a research team including staff scientists Joanne Morrisey, Michael Mather, and Sudipta Das, and advises graduate students April Pershing, Ming Yang, Lindsay Pomykala, and Suyash Bhatnagar. His work is supported by grants from the NIH and Medicines for Malaria Venture.

Rozalynne Samiraمشاهده پروفایل

استادیار

• Abiotic Stress Response
• Biotic Stress Response
• Molecular Biology
• +۳ مورد دیگر

Rozalynne Samira is a Research Assistant Professor in the Department of Plant and Soil Science at Texas Tech University's Davis College, affiliated with the Institute of Genomics for Crop Abiotic Stress Tolerance (IGCAST) and the Herrera-Estrella Lab. Her work focuses on developing grant-funded research programs to study stress response mechanisms in crops. Her educational background includes: Bachelor's and Master’s degrees in Biotechnology from Bangalore University, India M.Phil in Biochemistry and Molecular Biology from the University of Dhaka, Bangladesh PhD in Plant Biology from North Carolina State University Samira's research centers on cellular and molecular responses to abiotic and biotic stresses in Arabidopsis, jute, sorghum, and maize. With expertise spanning molecular biology, plant pathology, quantitative genetics, and cell imaging, she investigates stress tolerance mechanisms through genomic and molecular approaches. Her work aims to elucidate crosstalk between regulatory and metabolic pathways under environmental challenges. Analysis of her publication history reveals consistent focus on stress response mechanisms across multiple crops, with particular emphasis on transcription factors, defense signaling, and genomic tools for crop improvement. Her research bridges fundamental plant biology with agricultural applications, addressing both biotic threats like pathogen infections and abiotic challenges including nutrient deficiencies. Her scientific achievements include: National Science and Information & Communication Technology (NSICT) Fellowship Prime Minister Higher Education and Research Scholarship from the Government of Bangladesh Samira actively develops grant-funded research initiatives at Texas Tech while maintaining connections to her previous work at NC State University and the University of Dhaka. Though specific grant details aren't provided, her research trajectory indicates strong focus on agricultural resilience funding. She previously served as a lecturer at the University of Science and Technology Chittagong from 2005-2008. As a core member of IGCAST and the Herrera-Estrella Lab, she contributes to collaborative teams focused on crop stress genomics, utilizing facilities like the Fiber and Biopolymer Research Institute to advance sustainable agricultural solutions through molecular breeding and stress physiology research.

Fanny Elahiمشاهده پروفایل

دانشیار

• Vascular Cognitive Impairment (VCID)
• Neurodegenerative Diseases
• Biomarker Discovery
• +۷ مورد دیگر

Fanny Elahi is an Associate Professor at the Icahn School of Medicine at Mount Sinai, specializing in vascular cognitive impairment (VCID), neurodegenerative diseases, and biomarker discovery. Her research focuses on neurovascular mechanisms, blood-brain barrier dysfunction, and the development of novel biomarkers using extracellular vesicles and proteomics. She has contributed to studies on Alzheimer’s disease, cerebral small vessel disease, and the impact of systemic factors like atherosclerosis on brain health. Education: Graduated from the Icahn School of Medicine at Mount Sinai (ISMMS) in 2011. Her work integrates clinical neurology with biotechnology, particularly in microfluidics and bioprinting for tissue vascularization. She participates in collaborative projects such as the Clearance of Interstitial Fluid (ISF) and CSF (CLIC) group within the Vascular Professional Interest Area (PIA). Research interests span neuroimmunology, endothelial dysfunction, and the role of inflammation in brain aging. Key themes include sex differences in neurovascular health, retinal imaging as a biomarker for intracranial pathology, and the proteomic analysis of cerebrospinal fluid. Her recent studies highlight the therapeutic potential of targeting complement proteins and the clinical implications of plasma biomarkers like placental growth factor. Publications emphasize longitudinal cohort analyses (e.g., SPRINT-MIND trial follow-up), biomarker validation, and translational approaches in neurodegenerative diseases. She collaborates internationally on CADASIL consortium studies, focusing on early-phase VCID and genetic cerebrovascular diseases.

Xueliang Gaoمشاهده پروفایل

استادیار

• Cancer Biology
• Prostate Cancer
• Cancer Immunology
• +۴ مورد دیگر

Xueliang Gao is an Assistant Professor in the Department of Pharmacology & Immunology at the Medical University of South Carolina (MUSC). He holds a PhD and has extensive training, including postdoctoral work at Harvard Medical School and Dana-Farber Cancer Institute. His primary research focuses on cancer biology, with emphasis on molecular and metabolic signaling pathways in tumorigenesis, discovery of diagnostic markers, and development of therapeutic strategies targeting prostate cancer, cancer immunology, and the PI3K signaling pathway. Education & Experience: PhD from Georgia State University/Georgia Cancer Center for Excellence Postdoctoral training at Dana-Farber Cancer Institute and Harvard Medical School Prior role as an Instructor in Pathology at Harvard Medical School Research Interests: Elucidating roles of cell cycle proteins (e.g., CDK4/6, Cyclin D) in cancer progression Mechanisms of metabolic reprogramming in tumors, including pyruvate kinase M2 and PFKP functions Targeting PI3K/AKT/mTOR pathways and PTEN deficiency in castration-resistant prostate cancer Immunotherapy resistance and T-cell acute lymphoblastic leukemia pathogenesis Publications Trends: Recent work emphasizes therapeutic strategies for immunotherapy resistance, CDK6 signaling, and understanding metastatic pathways in prostate and pancreatic cancers. Key themes include enzyme multitasking (e.g., PFKP kinase activity) and cellular metabolism-drug interactions. Labs/Teams: Collaborates with multidisciplinary teams at MUSC and Harvard, focusing on translational cancer research and preclinical drug development. His lab investigates novel biomarkers and combination therapies for advanced cancers.

• Mycobacterial Cell Wall Biology
• Microbiology
• Immunology
• +۳ مورد دیگر

Dr. Takehiro Kado is an Assistant Professor in the Department of Biology at Missouri State University. His research focuses on the cell surface biology of mycobacteria, particularly the role of mycolic acids in cell wall synthesis and resilience. He employs advanced techniques like fluorescent microscopy, lipid extraction, and biochemical/click chemistry analyses. Kado holds a DVM from Kitasato University (2009), a PhD in Veterinary Science (2015), and completed a postdoc at the University of Massachusetts Amherst (2019). He teaches courses in immunology and pathogenic microbiology. His awards include the 2022-2023 Summer Research Award from the Institute for Applied Life Sciences and the 2017 Young Scientist Award from the Japanese Society of Veterinary Science. His work bridges microbiology, immunology, and infectious disease, with a focus on bacterial virulence mechanisms and membrane biology. Research highlights include studying mycobacterial membrane compartmentalization via tuberculostearic acid and the role of lipoarabinomannan in cell division. He investigates Vibrio vulnificus pathogenesis, including its role in necrotizing infections and chemotactic tissue invasion. His lab emphasizes translational research to combat antimicrobial resistance and improve treatment strategies for mycobacterial infections.

Olivia L. Francis-Boyleمشاهده پروفایل

استادیار

• Immunology
• Hematology Oncology
• Acute Leukemia Research
• +۳ مورد دیگر

Olivia L. Francis-Boyle, PhD, is an Assistant Professor in the Schools of Pharmacy and Medicine at Loma Linda University and Principal Investigator of an independent research program. She teaches immunology and endocrinology and focuses on acute leukemia mechanisms, therapeutic development, and drug modeling. Her research employs patient-derived xenograft (PDX) models, in vitro/in vivo approaches, and high-throughput sequencing. Education: PhD in Molecular Biology, Loma Linda University (2015) MS in Biomedical Science, Walden University (2011) BS in Biology, Andrews University (2005) Research Interests: Investigating cellular/molecular mechanisms of acute leukemias (AML/ALL), evaluating therapeutic candidates (biologics, small molecules, immunotherapies), and leveraging PDX models for precision medicine. Recent Article Trends: Her work spans leukemia drug development, TSLP signaling in B-ALL, and metabolic pathways in AML. Key themes include xenograft models, therapeutic screening, and molecular mechanisms. Grants & Advising: Principal Investigator: Combination anti-PD1 therapy and TILs for AML (2020-2025) Completed grants include TSLP in pediatric B-ALL (2012-2013) and Hyundai Hope on Wheels (2015-2016) Labs & Teams: Leads a lab training students/fellows in leukemia research, collaborating on preclinical drug models and translational studies.