جستجوی استاد راهنمای دانشگاهی

Jessica Gluckمشاهده پروفایل

استادیار

• Medical Textiles
• Nanotechnology
• Nonwovens
• +۷ مورد دیگر

Jessica Gluck is an Assistant Professor in the Department of Textile Engineering, Chemistry and Science at the College of Textiles, North Carolina State University. Her interdisciplinary work bridges textile science with biomedical engineering and regenerative medicine. Education: Postdoctoral Fellowship, University of California, Davis Ph.D. in Molecular, Cellular & Integrative Physiology, University of California, Los Angeles (2013) M.S. in Biomedical Engineering, University of California, Los Angeles (2008) M.S. in Biomedical Textiles, North Carolina State University (2007) B.S. in Textile Technology, North Carolina State University (2005) Her research focuses on Medical Textiles, Nanotechnology, and Nonwovens , particularly in developing functional biomaterials for tissue engineering and wound healing. She designs advanced fibrous scaffolds, hydrogels, and composite structures that interact with biological systems at the cellular level, emphasizing immunomodulation, biocompatibility, and dynamic culture environments. Her recent publications (2022–2024) demonstrate a strong trend in biomimetic and bioactive textile-based systems , including vascular grafts, electrospun scaffolds with growth factors, conductive nanocomposites, and antiviral textiles. These works span materials science, bioengineering, and clinical translation, often targeting corneal, cardiovascular, and soft tissue regeneration. Research Groups: Faculty Research: Medical Textiles Faculty Research: Nanotechnology Faculty Research: Nonwovens Academics: Textile Engineering, Chemistry and Science Academics: Textile Technology Dr. Gluck actively mentors students and leads research projects in advanced medical textile development. She has secured research funding (implied by active lab output) and collaborates across disciplines to innovate in healthcare solutions using engineered textiles. Her lab explores next-generation materials for regenerative medicine, including smart scaffolds, controlled drug delivery systems, and standardized testing for antiviral efficacy.

• Cancer Biology
• Virology
• Precision Medicine
• +۳ مورد دیگر

Kien Pham is a Research Scientist in Pathology at Yale School of Medicine, serving as Operations Manager for the YSM Biobank. She holds a Ph.D. in Biomedical Sciences from the University of Florida and completed postdoctoral training under Prof. Chen Liu. Her research focuses on cancer metastasis, precision medicine, and viral hepatitis, with contributions to SARS-CoV-2 genomic studies. Previously, she was an Assistant Professor at Rutgers New Jersey Medical School. Education: B.S. (2006, Molecular and Cellular Biology), M.S. (2008, Applied Biosciences), Ph.D. (2013, Biomedical Sciences) from the University of Arizona and University of Florida. Research Interests: Her work spans cancer biology, virology, and epigenetics, with recent emphasis on Omicron variant dynamics, CAR-NK therapy for hepatocellular carcinoma, and epigenetic drivers of liver disease. She leads collaborative projects on viral evolution and precision oncology. Key Achievements: Published over 20 peer-reviewed articles and book chapters. Awards include AIMS Awards (2020), Experimental Pathology Innovative Grant (2014), and Medical Guild Research Incentive Award (2010). Labs & Affiliations: Chen Liu Lab, Yale Pathology Department, YSM Biobank. Active in translational research and global health initiatives.

Michael J. Garabedianمشاهده پروفایل

استاد

• Nuclear Receptor Signaling
• Prostate Cancer Therapeutics
• Atherosclerosis
• +۵ مورد دیگر

Michael J. Garabedian is a Professor in the Departments of Microbiology and Urology at NYU Grossman School of Medicine. His research focuses on nuclear receptor signaling in disease contexts including prostate cancer, atherosclerosis, and stress-related disorders. He holds dual appointments and serves as Acting Vice Chair for Education in Microbiology. Education: PhD in Biochemistry from Brandeis University (advisor not specified), followed by a postdoctoral fellowship at University of California, San Francisco studying glucocorticoid receptor mechanisms. Joined NYU Langone in 1994 as an Assistant Professor, transitioning to full Professor and expanding into urology research. Research Interests: The lab employs cutting-edge approaches like CRISPR screens, single-cell RNA-seq, and spatial transcriptomics to study: Nuclear receptor regulation in macrophages and immune cells Novel prostate cancer therapies targeting androgen receptors LXRα signaling in metabolic/vascular diseases Glucocorticoid effects on neuronal function during stress Collaborates with Susan Logan's lab on peptoid-based drug development. Lab Structure: 4 main researchers including co-mentored MD/PhD students Sophie Ruff and Jeff Schneider. Maintains close ties with the Logan Lab through shared projects. Lab Location: Alexandria Center for Life Science - East Tower, Room 324. Active in training programs as Faculty Senate Representative.

Jason Cantorمشاهده پروفایل

استادیار

• Cancer Metabolism
• Immune Metabolism
• Physiologic Cell Culture Media
• +۷ مورد دیگر

Jason Cantor is an Assistant Professor at the University of Wisconsin–Madison , with joint appointments as an Investigator at the Morgridge Institute for Research and Faculty Affiliate in Biomedical Engineering . He is also a member of the University of Wisconsin Carbone Cancer Center and Wisconsin Blood Cancer Research Institute . Education: B.S. in Chemical Engineering (Cornell University), Ph.D. in Chemical Engineering (University of Texas-Austin), Postdoctoral Training (Whitehead Institute/MIT) His research focuses on metabolic regulation in hematological cancers and immune cells , particularly environmental influences on metabolism and metabolic vulnerabilities . He pioneered physiologic cell culture media to better model human conditions and explores applications in functional genomics and metabolomics . The 15 most recent publications highlight his interests in metabolic modeling , gene essentiality , and therapeutic enzyme engineering , with a strong emphasis on physiologic media and metabolic dependencies in cancer and immune cells. Scientific Awards: Hartwell Individual Biomedical Research Award, American Cancer Society Postdoctoral Fellowship, Koch Institute Ludwig Fellowship, Margaret and Herman Sokol Award, and multiple graduate fellowships As a principal investigator, Cantor mentors trainees in interdisciplinary approaches combining engineering principles with cell biology . His lab develops tools for metabolic reprogramming and target discovery , aligned with affiliations in Integrated Program in Biochemistry and other graduate programs.

Matt Havrdaمشاهده پروفایل

دانشیار

• Neurodegenerative Diseases
• Parkinson's Disease
• Neuroinflammation
• +۶ مورد دیگر

Matt Havrda is an Associate Professor in Biomedical Sciences and Associate Dean for Research and Scholarship at the University of New England College of Osteopathic Medicine. He earned his Ph.D. from the Graduate School of Biomedical Science and Engineering at the University of Maine and leads a research program focused on the molecular basis of Parkinson’s disease and neuroinflammation. Research Interests: Dr. Havrda's work centers on understanding how environmental exposures interact with the innate immune system to drive neurodegeneration, particularly in Parkinson’s disease. His research integrates molecular biology, immunology, and translational neuroscience, using cellular and animal models as well as patient-derived biofluids and post-mortem tissues. Key areas include NLRP3 inflammasome signaling, epigenetic regulation via DNA methylation, and identification of early biomarkers for disease progression. Publication Trends: His recent publications demonstrate a consistent focus on neuroinflammation, inflammasome activation, and gene-environment interactions in Parkinson’s disease. The studies utilize longitudinal human data, genetic models, and environmental toxin exposures to uncover mechanisms of disease and potential therapeutic targets. Scientific Awards: Ruth L. Kirschstein National Research Service Award (NINDS) Dartmouth SYNERGY Scholar Award for Clinical and Translational Research Target Validation Award from the Michael J. Fox Foundation Advising and Grants: While specific advisees are not listed, Dr. Havrda leads an active research laboratory. His work is currently supported by the National Institute for Environmental Health Sciences, indicating sustained federal funding for his investigations into environmental impacts on neurological disorders. Labs and Teams: Dr. Havrda collaborates extensively with interdisciplinary teams, including epidemiologists, immunologists, and neuroscientists. His lab employs cutting-edge techniques in molecular biology and epigenetics to study neurodegeneration, contributing to both basic science and clinical translation in Parkinson’s disease research.

Ileana M. Cristeaمشاهده پروفایل

دانشیار

• Virology
• Proteomics
• Molecular Biology
• +۱۳ مورد دیگر

Ileana M. Cristea is the Henry L. Hillman Professor of Molecular Biology and an Associate Professor in the Department of Molecular Biology at Princeton University. She serves as the Director of Graduate Studies and leads the Cristea Lab, which focuses on the interplay between virology and proteomics. Her research aims to understand cellular defense mechanisms against viruses and viral strategies for immune evasion. Dr. Cristea's research interests lie at the interface of virology, proteomics, and molecular biology. Her lab investigates dynamic host-virus interactions, including protein-protein and protein-nucleic acid interactions during infection, DNA sensing in the nucleus, innate immune responses to herpesviruses, the role of deacetylases (HDACs and SIRTs) in viral infections, and global remodeling of cellular organelles. She develops and applies advanced proteomic tools integrated with genomics, microscopy, and bioinformatics to study these processes. Her recent publications demonstrate a strong focus on herpesviruses and human cytomegalovirus (HCMV), exploring mechanisms of viral immune evasion, host defense via DNA sensors like IFI16, organelle remodeling, and targeted proteomic assays. The research leverages cutting-edge mass spectrometry and multi-omics approaches to uncover fundamental biological insights with therapeutic implications. Her scientific achievements have been recognized with several awards: Bordoli Prize, British Mass Spectrometry Society (2001) NIDA Avant-Garde Director Pioneer Award (2008) Human Frontiers Science Program Young Investigator Award (2009) Early Career Award in Mass Spectrometry, ACS NJ Section (2011) American Society for Mass Spectrometry Research Award (2012) Molecular & Cellular Proteomics Lectureship (2013) Mallinckrodt Scholar Award (2015) Dr. Cristea is actively involved in mentoring and education. She advises PhD students, including Ji Woo Park. She is a head instructor for the summer Proteomics Course at Cold Spring Harbor Laboratory and has taught workshops at major conferences (ASMS, HUPO). She holds leadership roles in professional organizations, serving on the Executive Board of US-HUPO and chairing the Infectious Disease initiative of HUPO World. She also serves on the editorial boards of several high-impact journals, including Molecular & Cellular Proteomics , Proteomics , and Journal of Proteome Research . The Cristea Lab operates as a multidisciplinary research team, fostering collaborations with groups worldwide. Their work is supported by partnerships with organizations like the CHDI Foundation (Huntington's disease) and the Paul G. Allen Family Foundation (organelle remodeling). The lab continues to develop innovative proteomic and computational tools, such as machine-learning pipelines for predicting protein interactions.

Derek S. Tanمشاهده پروفایل

استاد

• Chemical Biology
• Drug Discovery and Development
• Molecular Pharmacology
• +۳ مورد دیگر

Derek S. Tan is a tenured Professor and Chair of the Chemical Biology Program at the Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center (MSK). He also holds the Eugene W. Kettering Chair and is a Tri-Institutional Professor at Weill Cornell Medicine and The Rockefeller University. He directs the Tri-Institutional PhD Program in Chemical Biology since 2012. Education: BS in Chemistry from Stanford University (1995) PhD in Chemistry from Harvard University (2000) Tan's research focuses on diversity-oriented synthesis and rational drug design to develop chemical probes for cancer and infectious disease research. His work leverages natural product insights to address challenges in small-molecule discovery, including antibiotic development for Mycobacterium tuberculosis and Yersinia pestis , and novel methodologies for synthesizing complex molecular architectures. The lab's 15 most recent publications highlight advancements in chemical biology methodologies (e.g., ubiquitin probes, adenylation enzyme inhibitors), antibiotic development (targeting Gram-negative bacteria, tuberculosis), and structural innovations in macrocycle synthesis. These works reflect interdisciplinary collaborations and translational applications in both oncology and microbiology. Scientific Awards: Louise and Allston Boyer Young Investigator Award (2010) Dean's Award for Excellence in Teaching (2013) As an advisor, Tan has mentored over 30 graduate students, postdoctoral fellows, and research assistants in his lab. His Tri-Institutional Program fosters multidisciplinary training, while his lab affiliations span the Center for Experimental Therapeutics and Gerstner Sloan Kettering Graduate School. Labs & Collaborations: Sloan Kettering Institute Chemical Biology Program Tri-Institutional PhD Program in Chemical Biology Collaborations with Luis Quadri (Cornell), Paul Hergenrother, and others

• Genome Stability
• Chromatin Function
• Longevity and Anti-Aging
• +۵ مورد دیگر

Jessica K. Tyler, Ph.D. is a Professor of Pathology and Laboratory Medicine at Weill Cornell Medical College. She serves as Principal Investigator of the Laboratory of Epigenetics and Genomic Integrity and has been at Weill Cornell Medicine since 2015, after previously serving as a Tenured Professor at the University of Colorado School of Medicine and as a CPRIT Rising Star at MD Anderson Cancer Center. Dr. Tyler's research focuses on the molecular basis of genome stability, chromatin function, and longevity. Her lab uses budding yeast as a model system to study aging processes due to its conserved evolutionary pathways with humans. The Tyler lab investigates how epigenetics and chromosomal processes regulate DNA stability, why genome instability increases during aging, and how these processes contribute to cancer and neurodegenerative disorders. Current projects include studying aging and anti-aging mechanisms, epigenetics, and genomic integrity. Her laboratory has made significant contributions to understanding chromatin dynamics in DNA repair, including the discovery that the tardigrade protein Dsup can protect yeast genomes from damage and extend longevity. The lab's research combines molecular genetics in budding yeast, tissue culture studies, biochemistry, and next-generation sequencing approaches. Dr. Tyler has received numerous scientific awards including being named a Fellow of the American Association for the Advancement of Science (2017), a National Academy of Sciences Kavli Fellow (2011), and recipient of the AACR Woman in Cancer Research Charlotte Friend Memorial Award (2009). Fellow of The American Association for the Advancement of Science (2017) National Academy of Sciences Kavli Fellow (2011) University of Glasgow Tenovus Medal (2010) AACR Woman in Cancer Research Charlotte Friend Memorial Award (2009) Leukemia and Lymphoma Society Scholar (2005) Hans Krebs Prize in Biochemistry (1990) Dr. Tyler actively mentors students and postdocs, with numerous alumni now in academic and industry positions. She has been awarded multiple NIH grants including research on chromatin's role in the repair of radiation-induced damage and discovering molecular mechanisms that determine replicative lifespan. Her laboratory collaborates with researchers across institutions and maintains active participation in scientific symposiums focused on epigenetic regulation and genome integrity.

Hamed Jafar-Nejadمشاهده پروفایل

استاد

• Glycosylation
• Notch Signaling Pathway
• Developmental Biology
• +۶ مورد دیگر

Hamed Jafar-Nejad is a Professor in the Department of Molecular and Human Genetics at Baylor College of Medicine, affiliated with the Graduate School of Biomedical Sciences and the Program in Developmental Biology . He received his MD from Tehran University of Medical Sciences and completed postdoctoral training at the University of Ottawa and Baylor College of Medicine. Research Interests : Glycosylation and deglycosylation in Notch signaling, Alagille syndrome (biliary development), NGLY1 deficiency, and their roles in human disease pathophysiology. Key Projects : Development of mouse models for Alagille syndrome, identification of dosage-sensitive modifiers like Poglut1, and investigation of NGLY1's role in BMP and AMPK signaling using Drosophila and mouse models. Recent Publications focus on therapeutic strategies for Alagille syndrome via gene silencing, POGLUT1's role in muscular dystrophy, and deglycosylation's impact on metabolic and immune dysregulation. His work bridges Drosophila genetics and mammalian systems to uncover mechanisms for developmental disorders. Scientific Awards : Harrington Scholar-Innovator Award (2025), Alagille Syndrome Accelerator Awards (2019, 2015), Glycobiology Significant Achievement Award (2017), and others. Labs & Collaborations : Leads the Hamed Jafar-Nejad Lab, collaborating with Haltiwanger, Paradas, and Darabi groups. His team includes graduate students, postdoctoral fellows, and alumni now in academia and industry.

David Booneمشاهده پروفایل

استاد مدعو

• Microbiology & Immunology
• Cancer
• Cellular & Molecular Biology
• +۹ مورد دیگر

David Boone is an Adjunct Professor in the Department of Biology at the University of Notre Dame and a Professor of Microbiology and Immunology at Indiana University School of Medicine – South Bend. His research focuses on the molecular and immunological mechanisms underlying inflammatory bowel diseases (IBD), colon cancer, and obesity, with a strong emphasis on host-microbe interactions, autophagy, and intestinal barrier function. Adjunct Professor of Biology, University of Notre Dame (2021–Present) Professor of Microbiology and Immunology, Indiana University School of Medicine – South Bend (2021–Present) Adjunct Associate Professor, University of Notre Dame (2014–2021) Associate Professor, Indiana University School of Medicine – South Bend (2014–2021) Assistant Professor of Medicine, University of Chicago (2006–2013) Adjunct Assistant Professor, University of California, San Francisco (2004–2006) Education: Ph.D., University of Ottawa (1997) B.Sc., University of Waterloo (1989) Dr. Boone's research explores the role of key regulatory genes such as ATG16L1 and TNFAIP3 in intestinal inflammation and cancer. His lab uses genetically engineered mouse models to investigate how disruptions in autophagy, NF-kB signaling, and epithelial barrier integrity contribute to disease. A major focus is the protective effect of the ATG16L1 Thr300Ala variant in colorectal cancer through enhanced type I interferon production. His recent publications reveal a consistent trend in understanding immune regulation in the gut, particularly how genetic variants influence microbial interactions, epithelial cell function, and anti-tumor immunity. His work bridges molecular immunology, genetics, and microbiome science, contributing to translational insights in IBD and cancer. Scientific Awards: No awards explicitly mentioned in the text. Dr. Boone has advised numerous graduate students and postdoctoral researchers, many of whom have co-authored his publications. While specific grants are not listed, his sustained research output suggests active funding. His work involves collaboration across institutions, including the University of Chicago, UCSF, and various medical research centers. He leads a research lab focused on intestinal immunology, utilizing transgenic mouse models and human cell lines to dissect pathways involved in inflammation, autophagy, and cancer. The lab investigates microbial infiltration, mucus layer integrity, and immune cell responses in genetically susceptible hosts.

David Munnمشاهده پروفایل

استاد

• Tumor Immunology
• Immune Suppression
• Cancer Immunotherapy
• +۹ مورد دیگر

David Munn is a Professor at the Medical College of Georgia at Augusta University, with joint appointments in the Department of Pediatrics: Hematology/Oncology, Georgia Cancer Center, Pathology, Medicine, Biochemistry and Molecular Biology, and Cellular Biology and Anatomy. He serves as Co-Director of the Pediatric Immunotherapy Program, leading translational research in tumor immunology and immune suppression. His research focuses on the molecular mechanisms tumors use to evade immune detection, particularly through the IDO and BTK pathways. Key areas include: Regulation of regulatory T cells (Tregs) and tolerogenic dendritic cells in the tumor microenvironment Development of small-molecule inhibitors targeting immune checkpoints Design and immune monitoring of clinical trials combining IDO inhibitors with chemotherapy and radiation First-in-children trials for pediatric brain tumors His recent publications highlight work on BTK-IDO-mTOR axis inhibition, IDO inhibitor trials in melanoma, and mechanisms of immunosuppression in glioblastoma and aging. His research is supported by the National Institutes of Health and charitable foundations. Scientific contributions and service include: Published in high-impact journals including Science Immunology , Nature Immunology , and Immunity Chair, GCC Internal Promotion and Tenure Advisory Committee (2020) Chair, GCC PRMC (Protocol Review and Monitoring Committee) (2020) Member, GCC Director Search Committee (2019) Reviewer for professional journals (since 2015) Dr. Munn mentors a research team including postdoctoral fellows and research associates, and leads the Munn Lab at the M. Bert Storey Research Building. His work bridges fundamental immunology and clinical application, advancing novel immunotherapies for both adult and pediatric cancers.

• Gut Microbiome
• Paediatric Immunology
• Mucosal Immunology
• +۵ مورد دیگر

Dr. Mona Bajaj-Elliott serves as Associate Professor in the Department of Infection, Immunity & Inflammation at University College London's Great Ormond Street Institute of Child Health (Faculty of Population Health Sciences). She concurrently holds the position of Co-Departmental Graduate Tutor at UCL. External appointments include Lecturer for the MSc Cancer program at the University of Nottingham, External Reviewer for Oxford's MSc Experimental Immunology, membership on the British Society of Gastroenterology's Gut Microbiome for Health Expert Panel, and Scientific Officer at BoobyBiome since April 2022. Her educational background includes a PhD from Birkbeck College (1984) and a BSc (Hons) from the University of London (1980). Her research centers on the gut microbial-immune axis in pediatric contexts, with five primary focus areas: (a) Gut microbiome dynamics in hematopoietic stem cell transplantation outcomes, (b) Microbial metabolite impacts on gastrointestinal homeostasis, (c) Gut microbiome roles in infant development, (d) Microbiome contributions to antimicrobial resistance, and (e) Mucosal defense mechanisms in infection and food allergy. Her laboratory investigates host-microbe-food antigen interactions at mucosal surfaces. Analysis of her 15 most recent publications reveals dominant research themes in pediatric microbiome-immunology interfaces, with significant emphasis on stem cell transplantation, renal transplantation, and infant/maternal microbiome dynamics. Key methodological approaches include longitudinal microbiome tracking, metabolome analysis, and translational models of infection and inflammation. Her work consistently bridges basic microbial science with clinical pediatric applications. Teaching responsibilities encompass Module Directorship for Acute & Chronic Infectious Diseases (BSc Population Health Year 2), co-direction of Epidemiological Transition (BSc Year 1) and Personalised Medicine (MSc) modules, and cross-faculty instruction on gut microbiome roles in intestinal/extraintestinal health including mental health connections. Her work aligns with UN Sustainable Development Goal 3 (Good Health and Well-Being).

Min-Yao Jhuمشاهده پروفایل

پژوهشگر

• Parasitic Plants
• Host-Parasite Interactions
• Nitrogen Fixation
• +۴ مورد دیگر

Min-Yao Jhu is a Postdoctoral Research Associate at the Crop Science Centre , affiliated with the University of Cambridge and the Department of Plant Sciences . Her research focuses on plant-microbe interactions, parasitic plant biology, and nitrogen fixation mechanisms. University: University of Cambridge Department: Department of Plant Sciences Academic Rank: Researcher Key Research Areas: Parasitic Plants, Host-Parasite Interactions, Nitrogen Fixation, Plant Genetics Jhu's work explores the genetic and molecular regulation of symbiotic and parasitic plant interactions. Her recent publications highlight advancements in nitrogen fixation biology, parasitic plant resistance mechanisms, and spatial transcriptomics techniques for studying plant development. Her research has significant implications for sustainable agriculture, particularly in reducing reliance on chemical fertilizers and enhancing crop resilience against parasitic plants like Cuscuta campestris .

Andrew Ewaldمشاهده پروفایل

استاد

• Cancer Metastasis
• Breast Cancer
• Cell Biology
• +۴ مورد دیگر

Andrew Ewald, Ph.D., serves as the Virginia deAcetis Professor and Director of the Department of Cell Biology at Johns Hopkins University School of Medicine. His research focuses on understanding collective cell behaviors in tissue development and disease progression, with emphasis on breast cancer metastasis mechanisms. Dr. Ewald earned his B.S. in Physics from Haverford College and Ph.D. in Biochemistry and Molecular Biophysics from Caltech, followed by postdoctoral training at UCSF. The Ewald Lab develops innovative 3D culture systems to model tumor initiation, invasion, and metastasis, integrating cutting-edge microscopy, genetics, and bioinformatics. Research themes include: Cellular dynamics of breast cancer metastasis Molecular toolkits driving invasion programs Tumor microenvironment interactions (immune cells, fibroblasts) KRAS-dependent invasion heterogeneity Biomechanical regulation of dissemination Publication analysis reveals consistent focus on metastasis mechanisms using advanced organoid models, computational approaches, and in vivo systems. Recent work emphasizes spatial dynamics of cell migration, microenvironmental regulation of invasion, and therapeutic targeting of metastatic processes. Dr. Ewald founded the Cancer Invasion and Metastasis Program (CIM), coordinating >40 faculty across Johns Hopkins to translate basic research into clinical trials. Collaborations include patient advocacy groups (METAvivor, BCRF) and federal networks (NCI CTD2, PSOC). He currently advises seven graduate students investigating metastasis biology and epithelial dynamics.

• Cancer Biology
• Epithelial-Mesenchymal Transition (EMT)
• Cancer Stem Cells
• +۴ مورد دیگر

Sendurai Mani is the Dean's Professor of Translational Oncology and Professor of Medicine at Brown University’s Warren Alpert Medical School. His research focuses on the epithelial-mesenchymal transition (EMT), cancer stem cells, and tumor metastasis. He has made groundbreaking contributions, including demonstrating that EMT generates cells with stem cell properties (Mani et al., Cell 2008), linking EMT to metastasis, and developing tools for targeting mesenchymal cancers. PhD, Indian Institute of Science (2000) MS, Madurai Kamaraj University (1993) BS, Madurai Kamaraj University (1991) Mani’s research interests center on molecular mechanisms of cancer progression, particularly how EMT enables metastasis, therapeutic resistance, and tumor cell plasticity. His lab investigates: EMT-driven cancer stem cell generation Immune-tumor cell interactions in metastasis Therapeutic strategies for hybrid EMT phenotypes Single-cell profiling of tumor heterogeneity Development of EMT/CSC biomarkers Novel approaches to target mesenchymal cancers His publications (115+ articles) reflect cutting-edge work in EMT, cancer stem cells, and tumor immunology. Recent studies include functional single-cell analysis of extracellular vesicles in breast cancer and pan-cancer EMT gene profiling (EMTome resource). Scientific awards and honors include: V-Scholar (2008-2011) MD Anderson Research Trust Fellow (2008-2014) American Cancer Society Research Scholar (2012-2015) AAAS Fellow (2020-present) Sigma Xi Full Member (2021-present) Mani serves as: Director, Translational Research Disease Groups at Brown Director, Stem Cell Center at Brown Co-leader of the Mani Lab at Brown University