جست‌وجوی استاد و پژوهشگر

• Tissue Engineering
• Regenerative Medicine
• Stem Cell Biology
• +۵ مورد دیگر

Adetola B. Adesida serves as a full Professor in the Department of Surgery within the Faculty of Medicine & Dentistry at the University of Alberta . His laboratory focuses on developing autologous cell-based tissue engineering strategies for cartilage and meniscus repair, leveraging interdisciplinary collaborations between chemists, biologists, clinicians, and material scientists. PhD in Pharmacy, Victoria University of Manchester (1999) Postdoctoral Research, Wellcome Trust Centre for Cell-Matrix Research Dual Fellowship, Harvard University/Massachusetts General Hospital (2006) Marie-Curie Fellowship, European Commission (2007) Dr. Adesida's research centers on stem cell biology and tissue engineering for musculoskeletal regeneration, with emphasis on: Meniscus and articular cartilage repair mechanisms Stem cell-chondrocyte interactions in 3D microenvironments Bioreactor conditioning (hypoxia, dynamic compression) Sex-specific responses in knee osteoarthritis models Space-related microgravity effects on joint tissues His work bridges fundamental mechanobiology with clinical translation through industry partnerships like CellCoTec. Recent publications demonstrate a strong trend toward 3D bioprinting of nasal and meniscal tissues, sex-dimorphic responses in osteoarthritis, and space medicine applications . Key themes include bioink development, molecular characterization of fibrochondrocytes, and prevention of post-traumatic joint degeneration through regenerative strategies. CIHR Research Award (2013) Harvard University/Massachusetts General Hospital Fellowship (2006) European Commission Marie-Curie Fellowship (2007) Dr. Adesida leads the Orthopaedic Tissue Engineering Laboratory , directing multiple CIHR-funded projects on meniscus regeneration using mesenchymal stem cells. His research integrates advanced bioreactor systems for mechano-hypoxia conditioning and collaborates with aerospace initiatives through Canadian Space Agency partnerships. Current work explores simulated microgravity effects on human meniscus models and develops clinically applicable matrices incorporating bioactive molecules for cartilage formation.

• Liver Immunology
• Immune Tolerance
• Transplant Immunology
• +۵ مورد دیگر

Associate Professor Patrick Bertolino at the University of Sydney's Central Clinical School leads the Liver Immunology Program at the Centenary Institute. With 20+ years of international recognition in liver immunology , he pioneered discoveries about CD8+ T cell activation and hepatocyte-mediated immune tolerance , including the paradigm-shifting finding that liver-activated T cells are deleted via hepatocyte lysosomes. His work bridges transplantation immunology , chronic hepatitis , and malaria vaccine development using transgenic mouse models . Trained by immunology luminaries: Chantal Rabourdin-Combe (ENS-Lyon), Jacques Miller (WEHI), Barbara Fazekas de St Groth (Centenary Institute) Continuous NHMRC funding since 2000: 2 Program Grants, 6 Project Grants 2010 NHMRC Senior Research Fellowship Research Themes explore how the liver uniquely regulates immunity: Induces transplant tolerance via T cell deletion Exploits immune subversion in hepatitis B/C and malaria Develops gene therapy and mRNA vaccines for liver-targeted immunity Investigates hepatitis C reinfection post-transplant Article Trends show sustained focus on T cell-liver interactions , with recent work on mRNA vaccines (2023), neuroinflammation in GVHD (2024), and long-lived TRM cells in malaria (2025). Publications span high-impact immunology , hepatology , and transplantation journals . Awards include: 2010 NHMRC Senior Research Fellowship 2009 Centenary Institute student paper award 1999 Kevin Lafferty Prize for Autoimmunity 1997 University of Sydney U2000 Fellowship Teaching includes 3rd-year Immunology lectures (since 1998). Led liver immunology group since 2011, mentoring students and postdocs. Collaborates with Centenary Institute and National Hepatitis C Elimination Program .

Anne Kenworthyمشاهده پروفایل

استاد

• Biophysics
• Structural Biology
• Cell and Developmental Biology
• +۳ مورد دیگر

Anne Kenworthy is a Professor in the Department of Molecular Physiology and Biological Physics at the University of Virginia. Her research focuses on the architecture and function of biological membranes, with a particular emphasis on lipid rafts and caveolae in health and disease. Primary Appointment: Professor, Molecular Physiology and Biological Physics, University of Virginia Education: BA in Biology from Kenyon College, PhD in Cell Biology from Duke University School of Medicine Postdoctoral Training: Biophysics at Johns Hopkins University, Cell Biology at NIH Her work combines live cell imaging, biophysics, structural analysis, and biochemical approaches to investigate: How proteins and lipids cooperate to form lipid rafts Exploitation of rafts by bacterial toxins Cholesterol's role in Alzheimer's disease Caveolin-1 mutations in breast cancer and pulmonary hypertension Structural basis for caveolae formation Recent studies highlight lipid peroxidation effects on phase separation, caveolin mutation structural analysis, and toxin-membrane interactions. She has contributed extensively to understanding membrane microdomains through 15 recent publications spanning 2024–2020. Her lab employs advanced techniques including: Fluorescence Recovery After Photobleaching (FRAP) Single Particle Electron Microscopy AlphaFold2 Structural Prediction High-Content Imaging Platforms The research has implications for neurodegenerative diseases, cancer, and infectious disease mechanisms.

Victor Rizzoمشاهده پروفایل

استاد

• Cardiovascular Disease
• Vascular Biology
• Molecular Signaling
• +۵ مورد دیگر

Victor Rizzo, PhD, FAHA, is a Professor in the Department of Cardiovascular Sciences at the Lewis Katz School of Medicine, Temple University. His research focuses on molecular signaling mechanisms in vascular dysfunction, particularly exploring caveolae, mitochondria, and extracellular vesicles in diseases like atherosclerosis and aneurysm formation. His lab utilizes advanced microscopy, biochemistry, and in vivo/in vitro models to study organelle signaling in endothelial and smooth muscle cells. Education: PhD in Cell Biology (Angiogenesis) from New Jersey Medical School, followed by postdoctoral training in Mechanotransduction at the University of Pennsylvania and Caveolae studies at Harvard Medical School. BS in Biology from Farleigh Dickinson University. Key research areas include: caveolae as flow-sensing organelles, mitochondrial signaling in vascular health/disease, and extracellular vesicle-mediated communication. Recent work emphasizes mitochondrial fission's role in hypertension and aneurysm development, as well as therapeutic targeting strategies. Selected achievements include FAHA fellowship recognition. Major publications span over 30 years, focusing on angiotensin II signaling pathways, vascular remodeling mechanisms, and organelle biology. Collaborative projects explore exosome roles in intercellular signaling and novel therapeutic approaches targeting mitochondrial dynamics.

• Metabolic Regulation
• Neuroendocrinology
• Immunometabolism
• +۳ مورد دیگر

Alexander Jais is a neuroscientist and metabolic researcher leading the Junior Research Group on Diet-Induced Metabolic Alterations at the Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) in Leipzig, part of Helmholtz Zentrum München. His work focuses on how dietary signals interact with brain circuits to regulate energy balance and metabolic health. He holds a PhD from the Medical University of Vienna (2014) and completed postdoctoral training at the Max Planck Institute for Metabolism Research under Prof. Jens Brüning. Research Interests : His group studies neurobiological mechanisms linking diet, brain function, and metabolic disease. Key areas include: Neuronal circuits regulating appetite and glucose metabolism Immunometabolic interactions in obesity Blood-brain barrier adaptations to dietary challenges Grants & Recognition : EFSD/Novo Nordisk Future Leaders Program (2022) Deutsche Forschungsgemeinschaft (DFG) funding Lab Focus : The Jais-Lab employs advanced neuroscience tools to investigate how chronic overnutrition disrupts brain nutrient signaling pathways, with implications for developing novel therapies targeting metabolic diseases.

• Endocrinology
• Metabolism
• Lipid Droplet Biology
• +۳ مورد دیگر

Perry E. Bickel, M.D., is an Associate Professor in the Department of Internal Medicine at UT Southwestern Medical Center, where he joined the faculty in 2012. He serves as Chief of the Division of Endocrinology and holds the Daniel W. Foster, M.D., Distinguished Chair in Internal Medicine. His research focuses on lipid droplet biology and its implications for diabetes and obesity treatment. Yale University - B.A. in Philosophy and Classical Civilization UT Southwestern Medical Center - M.D. Massachusetts General Hospital - Internal Medicine Residency & Endocrinology Fellowship Harvard Medical School - Research Fellowship Whitehead Institute - Visiting Scientist Dr. Bickel’s research investigates cellular fat storage and utilization mechanisms, particularly lipid droplet dynamics in diabetes and obesity. His lab aims to develop safe therapeutic interventions targeting these processes. Publications span lipid droplet biology, insulin signaling, and metabolic diseases, with key contributions in lipid metabolism regulation (2021-1997). Awards include Best Doctor in America and D Magazine Best Doctor recognitions. American Board of Internal Medicine (Endocrinology, Diabetes, Metabolism) Member - American Diabetes Association, Dallas County Medical Society, Endocrine Society, Obesity Society

• Membrane Trafficking
• Cell Biology
• Caveolae Biology
• +۵ مورد دیگر

Professor Rob Parton is a Group Leader at the Institute for Molecular Bioscience (IMB), University of Queensland. His research focuses on membrane trafficking, cellular organization, caveolae biology, and lipid droplet function. He leads the Role of the cell surface in health and disease group, part of the Centre for Cell Biology of Chronic Disease. His work explores caveolae dynamics, nanoparticle delivery mechanisms, and lipid droplet roles in immunity. Professor Parton holds an ARC Laureate Fellowship investigating nanoparticle pathways in vivo . His lab uses advanced microscopy and zebrafish models to study membrane domains and disease mechanisms. Key interests include caveolae-mediated stress responses, T-tubule formation in muscle, and lipid droplet-driven innate immunity. Awards: ARC Laureate Fellowship Grants: Tracking nanoparticles (ARC), Lipid droplet immune hubs (ERC) Students: Le Nguyen, Lucas Thor, Navia John, Haolan Sun Team: Includes researchers like Dr. Tom Hall, Dr. Ye-Wheen Lim, and Dr. Harriet Lo His lab develops novel tools for drug delivery and explores mechanotransduction in epithelial cells. Current projects include zebrafish models for muscle diseases and nanovesicle engineering for therapy delivery.

Hong Chenمشاهده پروفایل

دانشیار

• Vascular Biology
• Atherosclerosis
• Lymphatic System
• +۵ مورد دیگر

Hong Chen is a Principal Investigator at Boston Children's Hospital and an Associate Professor of Surgery at Harvard Medical School . Their work bridges vascular biology, computational methods, and metabolic disease research, with a focus on atherosclerosis, diabetes, and lymphatic system regulation. Harvard Medical School, Department of Surgery Boston Children's Hospital, Chen Lab Research spans endothelial cell signaling , single-cell RNA sequencing , and metabolite-mediated communication . Key areas include: FOXM1/Dab2 pathways in diabetic wound healing Epsin proteins in atherosclerosis and lipid metabolism Development of MEBOCOST algorithm for metabolite-CRC detection CXCL12/CXCR4 in neuro-lymphatic communication VEGFR3 and caveolae inhibition in lymphatic fate determination Recent publications highlight machine learning applications for cell identity genes, metabolite signaling in adipose tissue, and transcriptional regulators in cardiovascular disease. No explicit scientific awards or student advisement details were found in the provided text.

Michael T. Linمشاهده پروفایل

دانشیار

• Neurodegenerative Diseases
• Alzheimer's Disease
• Mitochondrial Biology
• +۳ مورد دیگر

Michael T. Lin is an Associate Professor of Neuroscience at the Brain and Mind Research Institute and Associate Professor of Neurology at Weill Cornell Medical College, positions he has held since 2012. His academic background includes an A.B. from Harvard University (1988) and an M.D. from the University of California, San Francisco School of Medicine (1992). Dr. Lin's research focuses on molecular mechanisms of neurodegenerative diseases, with emphasis on: Alzheimer's disease pathology and amyloid processing Mitochondrial dysfunction in Parkinson's disease Synaptic plasticity and ion channel regulation Therapeutic strategies for neuroprotection Clinical biomarkers for prodromal neurodegeneration His publication record reveals consistent focus on Alzheimer's pathogenesis (amyloid dynamics, synaptic impairment), Parkinson's disease (mitochondrial DNA mutations), and neurotherapeutic development. Recent clinical work explores neurodevelopmental diversity and non-cognitive biomarkers in neurodegeneration. Current research support includes a 2023-2028 NIH/NIA grant as Principal Investigator for Longitudinal Follow up of Clinical Trial Participants For Brain Donation . No advising relationships or scientific awards are documented.

• Immunology
• Parasitology
• Host-Pathogen Interactions
• +۳ مورد دیگر

Nilda Rodriguez served as an Assistant Professor in the Department of Biology at the University of Northern Iowa from 2012 to 2015. Her research focuses on understanding immune responses to parasitic infections, particularly Leishmania species. She investigates host-pathogen interactions, macrophage biology, and the molecular mechanisms enabling parasitic survival within host cells. Rodriguez's work explores topics such as phagocytosis dynamics, lipid body formation in infected macrophages, and sex-related differences in disease outcomes. Her research highlights key pathways involved in Leishmania infection, including CR3 receptor-mediated phagocytosis, prostaglandin signaling, and caveolae-mediated entry mechanisms. Findings emphasize how parasites subvert host cellular processes to evade immune detection. Rodriguez has contributed to over 14 peer-reviewed articles since 2000, with recent work focusing on Leishmania pathogenesis and immune evasion strategies. She has not been associated with any scientific awards listed in available records. No advising or grant information is provided in the current dataset. Her research is centered within the Biology department, though no specific laboratory or team affiliations are documented.

Kerrie-Ann McMahonمشاهده پروفایل

پژوهشگر ارشد

• Cell Biology
• Molecular Biology
• Caveolar Biology
• +۳ مورد دیگر

Kerrie-Ann McMahon is a Postdoctoral Research Fellow at the Institute for Molecular Bioscience (IMB) of the University of Queensland . Her research focuses on cellular membrane structures, particularly caveolae, and their roles in cellular stress responses, lipid signaling, and disease mechanisms. She has contributed significantly to understanding caveola formation, dynamics, and interactions with cellular processes like oxidative stress and cancer progression. Key research interests include: Caveolar biology and dynamics Oxidative stress signaling pathways Proteomic analysis of cellular interactions Membrane lipid regulation and ferroptosis Cancer cell invasion mechanisms Collaborations with researchers like Prof. Robert G. Parton highlight her work in membrane microdomains and their functional implications. While no formal advisees are listed, her publications reflect extensive teamwork in molecular and cellular biology. Her studies bridge basic science with translational applications, particularly in oncology and cellular stress biology.

Yeping Wuمشاهده پروفایل

پژوهشگر ارشد

• Cell Biology
• Cancer Research
• Molecular Biology
• +۵ مورد دیگر

Dr. Yeping Wu is a Postdoctoral Research Fellow at the Institute for Molecular Bioscience, The University of Queensland. Their research focuses on caveolae biology, oxidative stress response, and their roles in cancer progression, particularly ovarian and prostate cancers. Wu has contributed to studies on Cavin proteins, lipid peroxidation, and autophagy-dependent exosome secretion. Doctor of Philosophy (PhD), The University of Queensland (2019) Research interests include caveolae formation , oxidative stress regulation , epithelial-mesenchymal transition (EMT) , apoptosis mechanisms , and autophagy/exosome dynamics . Recent work (2023–2025) explores structural flexibility of Cavin1 domains and NRF2 pathway regulation via caveolae. Earlier studies (2014–2017) investigate chemopreventive flavonoids and MDM2’s role in cancer metastasis. Available for PhD/Master’s supervision

Suzanne Frances Scarlataمشاهده پروفایل

استاد

• Cell behavior
• Calcium signals
• Membrane-associated proteins
• +۷ مورد دیگر

Suzanne Frances Scarlata is a Professor of Chemistry and Biochemistry at Worcester Polytechnic Institute (WPI), where she has been a faculty member since 2016. She holds an affiliated position in the Department of Biology & Biotechnology. Her education includes a BA from Temple University (1979) and a PhD from the University of Illinois, Urbana-Champaign (1985). Previously served as Professor of Physiology and Biophysics at Stony Brook University (1991–2016). Formerly an Assistant Professor at Cornell University Medical College and a researcher at AT&T Bell Laboratories. Leading expert in cellular signaling pathways, particularly G protein-mediated processes and calcium signaling. Her research focuses on how small molecules and hormones activate G proteins to regulate cell behavior, including cell movement, division, and structural changes. Key areas include G protein signaling pathways, membrane-associated proteins, and stress granule formation. She has pioneered studies on the interplay between G proteins, calcium signals, and RNA translation. Notable contributions include the development of an enzymatic self-healing construction material with carbon-negative properties, supported by grants exceeding $10M from NIH, the American Heart Association, and others. This material uses enzymes like carbonic anhydrase to precipitate calcium carbonate, offering sustainable alternatives to traditional concrete. Awarded over $10M in research funding, Scarlata has been a keynote speaker at major scientific conferences and serves as an associate editor of Journal of Bioenergetics and Biomembranes and on editorial boards of Journal of Fluorescence , Journal of Membrane Biology , and others. Her interdisciplinary work spans BioPoint and MatR: Materials Reimagined initiatives, addressing sustainable development goals. The Scarlata Lab investigates biophysical methods to study signaling pathways, emphasizing membrane dynamics and cellular responses to stimuli. Professional highlights include election as a AAAS Fellow (2020), Georgina Sweet Award (2016), and leadership roles in the Biophysical Society.

Ajit Tiwariمشاهده پروفایل

استادیار

• Membrane Trafficking
• Bacterial Toxin Endocytosis
• Angiogenesis
• +۴ مورد دیگر

Ajit Tiwari is an Assistant Professor at the University of Virginia, affiliated with the Department of Molecular Physiology and Biological Physics. His research focuses on membrane trafficking, bacterial toxin internalization, and protein dynamics in Alzheimer's disease. Research Interests: Membrane Trafficking, Bacterial Toxin Endocytosis, Angiogenesis, Alzheimer's Disease. Key Themes: Clathrin-Independent Endocytosis, Plasma Membrane Organization, Caveolae Formation. His work explores the role of microtubules, motor proteins, and membrane domains in endocytic pathways and disease-related protein partitioning. Studies span molecular mechanisms of toxin uptake and amyloid precursor protein behavior in neurodegeneration. Recent publications highlight collaborations on high-content imaging, cholera toxin biology, caveolae dynamics, and cytoskeletal regulation of endocytosis. He has contributed to understanding ER retention signals in vascular diseases and aggresome formation.

Karl Swärdمشاهده پروفایل

استاد

• Cardiovascular Physiology
• Mechanotransduction
• Hypertension Research
• +۷ مورد دیگر

Karl Swärd is a Professor and Research Team Manager at Lund University's Faculty of Medicine, where he leads research in cellular biomechanics as part of the Proactive Ageing profile area. His work focuses on understanding how mechanical forces translate into biochemical signals, particularly in cardiovascular contexts. Dr. Swärd's research interests span cardiovascular physiology, mechanotransduction, and vascular biology. He investigates how hypertension translates into cardiovascular disease, with specific focus on the NOTCH signaling pathway, caveolae function, and thrombospondin-4 (Thbs4) mechanisms. His work has established connections between hypertension-driven stroke and syndromic stroke through NOTCH pathway involvement. He also studies caveolinopathies using mouse models and examines the genetic control mechanisms of caveolae formation through myocardin family coactivators. His recent publication trends reveal strong focus on mechanoresponsive genes and their role in cardiovascular and renal pathologies. His work spans from fundamental cellular biomechanics to translational applications in hypertension, aneurysm development, and bladder fibrosis. His research demonstrates interdisciplinary connections between cardiovascular, renal, and urological systems through shared molecular mechanisms. Dr. Swärd currently leads multiple research projects including studies on mechanoregulated transcription factors in vascular aging, LL-37-induced cytotoxicity, anti-inflammatory treatments for Moyamoya disease, and vascular signaling in hypertension. His laboratory collaborates extensively within Lund University and internationally, with work contributing to UN Sustainable Development Goals related to health and wellbeing.