جست‌وجوی استاد و پژوهشگر

Berenice A. Benayounمشاهده پروفایل

دانشیار

• Aging and Longevity
• Epigenetics
• Transcriptomics
• +۵ مورد دیگر

Bérénice Benayoun, PhD is an Associate Professor at the USC Leonard Davis School of Gerontology , with secondary appointments in the Department of Molecular and Computational Biology (USC Dornsife College of Letters, Arts and Sciences) and the USC Norris Comprehensive Cancer Center . Her research bridges aging biology , epigenetics , and sex differences using vertebrate models like the African turquoise killifish and machine learning . Education : École Normale Supérieure (BSc, MSc), Paris Diderot-Paris 7 University (PhD in Genetics and Cell Biology) Her lab investigates epigenome and transcriptome remodeling during aging , focusing on how biological sex influences these processes. Key themes include inflamm-aging , genomic instability , and immune senescence , with applications in neurodegeneration and reproductive longevity . Recent publications highlight sex-dimorphic gene regulation in neutrophils , macrophages , and brain aging , alongside novel insights into transposable elements and MOTS-c mitochondrial signaling . She pioneers the use of single-cell transcriptomics and multi-omics in aging research. Scientific awards include: 2024 Vincent Cristofalo Rising Star in Aging Research Award 2023 AGHE Rising Star Early Career Faculty Award 2023 USC Mentoring Award 2023 Rising Star in Reproductive Biology 2021 Nathan Shock New Investigator Award 2019 Rosalind Franklin Young Investigator Award Her editorial roles include Geroscience , Translational Medicine of Aging , and eLife . She mentors students across PhD programs in Biology of Aging , Neuroscience , and Molecular Medicine , as well as Master's and undergraduate trainees.

• Regenerative Medicine
• Cardiovascular Development
• Genomics
• +۵ مورد دیگر

Mirana Ramialison is a Professor at Monash University, affiliated with both the Australian Regenerative Medicine Institute and Victorian Heart Institute (VHI). She maintains an active research program with significant contributions to cardiovascular development and regenerative medicine. Her research interests focus on understanding the role of non-coding DNA regulatory elements in heart development and disease, formation of boundaries in developing embryos, and molecular mechanisms underlying cardiac function. She employs cutting-edge genomic, computational, and imaging approaches to investigate gene regulatory networks that govern cardiovascular development. Her recent publications demonstrate expertise in spatial transcriptomics, machine learning applications in epigenomics, and the use of vertebrate models like the African killifish to study aging processes. Her work spans developmental biology, genomics, and computational approaches to understand heart development and disease mechanisms. Professor Ramialison leads multiple significant research projects including 'Role of human non-coding DNA regulatory elements (REs) in heart development and disease' as Primary Chief Investigator, and collaborates on projects related to chemotherapy-induced heart damage prevention and bone growth mechanisms. She has produced 71 research outputs with notable recent publications in high-impact journals including Nature Cardiovascular Research, Genome Biology, and Communications Biology, demonstrating sustained scholarly productivity and impact in her field.

Vasanta Subramanianمشاهده پروفایل

دانشیار

• Developmental Biology
• Stem Cell Biology
• Neurodegenerative Diseases
• +۱۳ مورد دیگر

Vasanta Subramanian is a Reader in the Department of Life Sciences at the University of Bath, Faculty of Science. She is an active researcher and supervisor, leading multiple projects focused on developmental biology, stem cell regulation, and neurodegenerative diseases. Her lab uses advanced models including murine systems, zebrafish, killifish, and human iPSC-derived organoids to investigate molecular mechanisms in organogenesis and disease. Department: Department of Life Sciences Position: Reader (equivalent to Associate Professor) Email: V.S.Subramanian@bath.ac.uk Location: 4 SOUTH 0.67, University of Bath ORCID: 0000-0002-1969-7333 Research Interests: Dr. Subramanian's research centers on understanding the molecular basis of development and disease. Her lab investigates three interconnected areas: (1) stem cell regulation in intestinal and brain epithelia, (2) the role of Cdx, polycomb, and trithorax genes in axial development, and (3) the function of angiogenins and cytotoxic ribonucleases in health and disease, particularly in ALS and Alzheimer’s. She employs CRISPR/Cas9, organoid models, and transgenic animals to dissect gene function and disease mechanisms. Recent Research Trends: Her recent publications (2020–2024) reflect a strong focus on neurodevelopment, ciliopathies, and neurodegenerative disorders. Key themes include the role of primary cilia in neural development, the impact of angiogenin mutations in ALS, and the use of novel models like the African turquoise killifish for aging and neurodegeneration studies. Her work bridges basic developmental biology with translational research in dementia and motor neuron diseases. Scientific Funding and Projects: Principal Investigator, Developing the African Turquoise killifish as a novel model for Neurodegenerative Disease – Alzheimer's Research UK Principal Investigator, Developing the rapidly aging Nothobranchius furzeri as model to study Motor neurone disease – Motor Neurone Disease Association Principal Investigator, Targeting intracellular Aß-peptide by Neprilysin in a human iPS cell organoid model – UK charity funding Co-Investigator, Understanding the molecular basis of Aß peptide interacting proteins in Alzheimer's disease – UK charity Principal Investigator, Harnessing CRISPR/Cas9 technology to develop new models of Alzheimer's disease Supervision and Collaborations: Dr. Subramanian is actively supervising doctoral students and welcomes PhD inquiries. She has advised at least five research students. Her collaborations include Professor K.R. Acharya (University of Bath), Dr. Greg Elgar (Queen Mary University of London), and Dr. Anand Chandrasekhar (University of Missouri, USA), focusing on angiogenic molecules and zebrafish genomics. Professional Memberships: Biochemical Society British Society for Developmental Biology (BSDB) Genetics Society Anatomical Society Indian Society of Cell Biology (Life Member)

Krishni Wijesooriyaمشاهده پروفایل

استاد

• Medical Physics
• Radiation Oncology
• Biomedical Engineering
• +۹ مورد دیگر

Krishni Wijesooriya is a Professor of Radiological Physics at the University of Virginia , holding a Ph.D. from the College of William and Mary (1999). Her research focuses on Medical Physics and Radiation Oncology , particularly on techniques for tumor localization, motion correction, and patient safety improvements in radiation therapy. Ph.D., 1999, College of William and Mary Professor of Radiological Physics, University of Virginia Her work spans Radiation Therapy innovation, including Monte Carlo algorithms for lymphocyte dose prediction, real-time MLC monitoring software for Varian Linacs, and novel diagnostic imaging tools complementary to CT/MRI/PET. She also contributes to global oncology projects in SAARC countries and Africa. Recent publications include developments in Immune Cell Sparing (2025) and Phylogenetic Studies of Sri Lankan fish species (2021–2024). Key collaborations appear in Lancet Oncology , Advances in Radiation Oncology , and PLoS Computational Biology . Her email is kw5wx@virginia.edu .

Anne Brunetمشاهده پروفایل

استاد

• Aging
• Longevity
• Neural Stem Cells
• +۷ مورد دیگر

Anne Brunet holds the Michele and Timothy Barakett Endowed Professorship in the Department of Genetics at Stanford University School of Medicine. She is a leading researcher in the field of aging and longevity with extensive affiliations across multiple Stanford institutes including the Bio-X Program, Cardiovascular Institute, Wu Tsai Human Performance Alliance, Stanford Cancer Institute, and Wu Tsai Neurosciences Institute. Dr. Brunet's research focuses on the molecular mechanisms of aging and longevity, with special emphasis on the nervous system. Her lab investigates pathways involved in delaying aging in response to external stimuli such as nutrient availability and mates, mechanisms influencing the rejuvenation of old stem cells, and has pioneered the use of the naturally short-lived African killifish as a model to explore aging regulation and age-related diseases. She has a long-standing interest in the insulin-FOXO transcription factor pathway, which regulates lifespan from worms to humans, and studies how longevity genes maintain adult neural stem cells and cognitive function during aging. Analysis of her recent publications (2023-2025) reveals a strong focus on spatial transcriptomics of brain aging, CRISPR-Cas9 screening for aging regulators in neural stem cells, protein aggregation in aging vertebrates, and the development of the African killifish as a model organism. Her work integrates cutting-edge technologies including single-cell and spatial transcriptomics, high-throughput genetic screening, and multi-omics approaches to study aging across tissues. Scientific Awards: Transformative Research Award, NIH Directors' Fund (2018) Pioneer Award, NIH Director's Fund (2012) Senior Scholar Award, Ellison Medical Foundation (2009) Alfred P. Sloan Fellow, Sloan Foundation (2006) Multiple awards for mentoring and aging research Dr. Brunet actively mentors numerous graduate students and postdocs, serving as Doctoral Dissertation Advisor, Co-Advisor, and Reader for over 15 students, and sponsoring 7 postdoctoral fellows. She teaches courses including Current Issues in Aging and multiple directed reading/research courses in Genetics, Neurosciences, and Stem Cell Biology. Her lab, the Brunet Lab, is part of the Paul F. Glenn Laboratories for the Biology of Aging and focuses on understanding the genetic mechanisms of aging through multiple complementary approaches including mammalian models, C. elegans, and the African killifish.

Alexandra Tyersمشاهده پروفایل

پژوهشگر

• Evolutionary Biology
• Speciation Mechanisms
• Molecular Ecology
• +۳ مورد دیگر

Alexandra Tyers is a Post-Doc Researcher at CIBIO-InBIO, University of Porto. Her research focuses on interdisciplinary studies of speciation and adaptation in desert rodents and African fish, employing fieldwork, molecular ecology, and microbiome analysis. She holds a PhD from Bangor University (UK) and conducted postdoctoral work at the Max Planck Institute for Biology of Ageing (Germany). Current projects investigate Sahara-Sahelian rodent divergence through pre/post-zygotic mechanisms and environmental adaptation hypotheses. Her work bridges evolutionary genetics, ecology, and conservation. Education: PhD in Molecular Ecology (Bangor University, 2014), followed by postdoctoral research at Max Planck Institute (2017–2020). Research expertise includes speciation genetics in cichlids, killifish aging biology, and microbiome-driven adaptation. She managed Dr. Valenzano’s lab, exploring life-history and microbiome divergence in African killifish. Research Interests: Mechanisms of speciation, adaptation to extreme environments, evolutionary genomics, microbial ecology, and behavioral ecology. Her work addresses how species diverge through genetic, epigenetic, and ecological processes, with applications to conservation biology. Publications highlight epigenetic divergence in African cichlids, killifish aging mechanisms, and invasive species dynamics. She contributes to projects on Lake Malawi cichlid radiations and Saharan rodent evolution. Her lab collaborations emphasize integrative approaches to evolutionary questions.

Ryan MacDonaldمشاهده پروفایل

دانشیار

• Neurosciences
• Ophthalmology
• Glial Biology
• +۵ مورد دیگر

Ryan MacDonald is an Associate Professor at University College London's Institute of Ophthalmology, where he leads a research group focused on understanding eye development and maintenance throughout life. His laboratory investigates how glial cells pattern and shape during development to support neurons, and what happens when the glia-neuronal relationship breaks down due to aging or disease. Current position: Associate Professor, Institute of Ophthalmology, University College London (Sep 2023 - present) Previous appointments: Senior Research Fellow at UCL, Postdoctoral Fellow at Linkoping University, Research Associate at University of Cambridge Education: PhD in Neurobiology from University of Ottawa, BSc Hons from University of New Brunswick Dr. MacDonald's research primarily centers on glial biology within the retina using zebrafish as a model system. His lab leverages the transparency of zebrafish embryos to label specific cells with fluorescent markers and use time-lapse confocal microscopy to observe eye development in real time. The group employs CRISPR/Cas9 mutagenesis, RNA-sequencing, and molecular biology techniques to uncover fundamental mechanisms of glial biology, with particular interest in cellular and molecular mechanisms regulating glial morphogenesis and the consequences of disrupted glial contacts on neuronal function. Analysis of Dr. MacDonald's recent publications reveals a strong focus on retinal development, aging mechanisms, and neurodegenerative processes. His work spans multiple model systems including zebrafish and African turquoise killifish, with significant contributions to imaging technology through the IBEX Knowledge-Base project. His research bridges basic developmental biology with translational applications for understanding age-related eye diseases. Associate Fellow Higher Education Academy BBSRC David Phillips Fellowship (2019-2024) Dr. MacDonald actively supervises multiple PhD students including Ola Krzywańska (Moorfields Eye Charity PhD Student), Gina Gilpin (BBSRC LIDo Programme PhD Student), and Roxana Lungu (Moorfields Eye Charity PhD Student). His lab is supported by various funding sources including Moorfields Eye Charity and the BBSRC. The MacDonald Lab is part of several graduate programs at UCL including the UCL-Birkbeck MRC Doctoral Training Programme and the London Interdisciplinary Doctoral Programme. The MacDonald Lab maintains active collaborations and has developed important resources including the GliaMorph toolkit for quantifying Müller glial cell morphology and contributing to the IBEX Knowledge-Base for multiplexed imaging techniques. Their research has significant implications for understanding age-related macular degeneration, Parkinson's disease mechanisms, and retinal neurodegeneration.

• Neurobiology
• Aging Research
• Neural Regeneration
• +۷ مورد دیگر

Godelieve Moons serves as a full Professor in the Department of Biology at the Faculty of Sciences, KU Leuven. She leads research within the Animal Physiology and Neurobiology unit and holds key affiliations with the KU Leuven Brain Institute (LBI), KU Leuven Institute for Rare Diseases (Leuven.IRD), and KU Leuven Institute for Single Cell Omics (LISCO). Her institutional roles include membership in the Faculty Council of Sciences, Departmental Council of Biology, and specialized Program and Oversight Committees (POCs) for Biochemistry, Biotechnology, and Sexological Sciences. Her research centers on neurobiological mechanisms of aging and regeneration , with particular focus on glial cell dynamics, myelin integrity, and axonal repair. Using the rapidly aging African turquoise killifish as a primary model, she investigates how intraneuronal energy redistribution drives functional recovery in the central nervous system, explores non-mitochondrial metabolic pathways for axon regrowth, and examines age-related glial changes impacting remyelination. Her work bridges fundamental neurobiology with therapeutic development for neurodegenerative conditions and healthy brain aging. Analysis of her 2025 publications reveals a cohesive research trajectory centered on killifish models to decode aging-related neural decline. Key thematic clusters include oligodendroglial heterogeneity in myelin dynamics, metabolic reprogramming for neural repair, and the interplay between mitochondrial function and regeneration capacity. Her studies consistently integrate single-cell omics, in vivo genome editing, and functional recovery metrics to identify therapeutic targets for conditions like Wolfram syndrome and age-related neurodegeneration. Professor Moons actively supervises doctoral candidates including Faneca Santos, J. and Marien, V., while leading multiple major research initiatives. She currently serves as Promotor for six projects and Co-promotor for four others, including "Herverdeling van intraneuronale energie stuurt functioneel herstel" (2022-2026), "Onderzoek naar leeftijdsgerelateerde gliale veranderingen" (2022-2028), and "Gezond ouder worden met behulp van waardevolle lignine-derivaten" (2024-2027), collectively securing substantial funding for neural regeneration research. Her laboratory operates within KU Leuven's BioScience Center infrastructure, utilizing advanced platforms including killifish R&D systems for drug screening, stem cell-derived optic nerve-on-chip models, and in vivo genome editing techniques. The team collaborates extensively through the LBI and Leuven.IRD networks to translate findings into therapeutic strategies for neurodegenerative diseases and healthy aging interventions.

Christoph Englertمشاهده پروفایل

پژوهشگر

• Molecular Biology
• Developmental Biology
• Aging Research
• +۳ مورد دیگر

Christoph Englert is a Group Leader at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) , focusing on molecular and developmental biology, genetics, and aging research using short-lived vertebrates like Nothobranchius furzeri (turquoise killifish). His team investigates the role of Wilms tumor proteins (Wt1, Wtx) in tissue development, kidney regeneration, and aging pathways, employing zebrafish and killifish models. Research Interests: Wt1 target genes, Wnt signaling, kidney regeneration, sex determination, age-dependent gene expression, and mutation rate analysis. Team Members: Includes doctoral candidates (Carolin Albertz, Hanna Mörl), master's students (Abhishek Pragnesh Patel, Annika Herfurth), and technical staff. Article Trends: Recent publications (2023–2025) explore Wt1/Wtx functions in fibrosis, Wnt pathway roles in zebrafish kidney repair, evolutionary genetics of killifish sex determination, and mutation rates in nonaging organisms. Earlier work (2008–2013) established foundational insights into urogenital development, aging biomarkers, and CRISPR/Cas9 tools. Key Collaborations: Projects with DFG Excellence Clusters, Carl Zeiss Foundation, and Leibniz Research Alliance on aging and regeneration. Infrastructure: Utilizes core facilities like functional genomics, proteomics, and small animal CT at FLI.

• Medical Genetics
• Neurosciences
• Genetics

Dr. Nicole Noel is an Honorary Research Fellow at the Institute of Ophthalmology, University College London. Her primary research focuses on genetic and neuroscientific aspects of retinal disorders, particularly leveraging animal models like the African turquoise killifish and zebrafish to study aging-related pathologies and inherited diseases. She holds a PhD in Medical Genetics from the University of Alberta, Canada. Her work emphasizes retinal degeneration mechanisms, photoreceptor biology, and translational applications of single-cell genomic technologies. Key research areas include macular degeneration, ciliary dysfunction, and pigmentary glaucoma. Dr. Noel’s studies frequently involve advanced imaging techniques (e.g., IBEX) and genetic sequencing to uncover disease pathways. Publications from 2021–2024 reveal a focus on aging retinal transcriptomes, killifish as aging models, and zebrafish as platforms for studying photoreceptor diseases. Her research bridges basic science with clinical insights into vision loss mechanisms.

Ginger E. Carneyمشاهده پروفایل

استاد

• Genetics
• Behavioral Genetics
• Social Behavior
• +۳ مورد دیگر

Ginger E. Carney is a Professor and Dean of the College of Science at the University of Idaho. She holds a B.S. (1991) and Ph.D. (1998) in Genetics from the University of Georgia, followed by an NIH-funded postdoctoral fellowship at Oregon State University. Her career includes faculty roles at Georgia Institute of Technology and Texas A&M University before joining the University of Idaho in 2017. Her research focuses on the genetic and physiological mechanisms underlying social behaviors, particularly in Drosophila melanogaster and African killifish (Nothobranchius). Key areas include reproductive behavior modulation, adipose-tissue signaling, and the role of miRNAs in behavioral regulation. She employs genetic, transcriptomic, and molecular approaches to decode gene interactions and their effects on behavior. Carney has received numerous honors, including the University of Idaho Spring Commencement speaker role (2021), Western Academic Leadership Academy fellowship (2018–2019), and teaching awards at Texas A&M. Her work bridges molecular genetics, physiology, and evolutionary biology, with implications for understanding behavioral adaptations in diverse species. Her research is supported by NIH grants and collaborations, and she leads a lab exploring topics such as diet’s impact on behavior and the evolutionary basis of mating preferences. She actively mentors students and contributes to academic leadership initiatives.

• Animal Physiology
• Fish Physiology
• Environmental Adaptation
• +۵ مورد دیگر

Mery Martinez Garcia is an Associate Professor in the Department of Biology at Laurentian University's School of Natural Sciences, specializing in animal physiology with focus on fish adaptation to environmental stressors including hypoxia, temperature fluctuations, and food availability. Her research integrates physiological, biochemical, behavioral, and ecological methodologies to examine energetic metabolism and reproductive fitness across diverse aquatic species. Education: PhD in Biology (Fish Physiology), Université Laval, Québec, Canada MSc in Biology (Fish Physiology), Université Laval, Québec, Canada BSc in Biology, Pontificia Universidad Javeriana, Bogota, Colombia Research Focus: Dr. Martinez Garcia investigates how environmental changes impact physiological traits in fish, with current projects examining hypoxia effects on reproductive fitness in African cyprinids, energy trade-offs in electric fish communication, and global warming impacts on shark embryonic development. Her work combines field studies with laboratory analyses to understand adaptive mechanisms at molecular, organismal, and population levels. Recent research emphasizes climate change vulnerabilities in early developmental stages of marine species. Publication Trends: Her 15-year publication record demonstrates consistent contributions to fish physiology, showing progression from foundational studies on cod swimming performance to contemporary research on climate change impacts. Key themes include metabolic plasticity under environmental stress, reproductive adaptations to hypoxia, and interspecies comparisons of physiological responses across diverse fish taxa. Awards: Laurentian University Students Teaching Award (2015) Ph.D. Bourse d’excellence from Québec Government (1997–2000) Travel fellowship for International Congress of Comparative Physiology and Biochemistry (1999) Multiple Québec Government tuition exemptions and departmental fellowships (1994–2001) ICETEX-Colombia scholarship for Master's studies (1994–1996) Collaborations and Mentoring: Dr. Martinez Garcia mentors students in physiological research methods while maintaining international collaborations including Dr. Luis Fernando DeLeón (Boston University) on electric fish communication and Dr. Gillian Renshaw (Griffith University) on shark embryology. Her work receives support through institutional resources rather than specific grant mentions in the provided text. Research Environment: Her laboratory investigates environmental physiology through integrated approaches, currently focusing on dissolved oxygen effects, thermal tolerance, and reproductive adaptations in fish models ranging from cyprinids to sharks, with emphasis on anthropogenic environmental change impacts.

Xiaolei Xuمشاهده پروفایل

استاد

• Cardiovascular Disease Research
• Genetic Modifiers of Cardiomyopathy
• Zebrafish Genetics
• +۳ مورد دیگر

Xiaolei Xu, Ph.D., is a Professor of Biochemistry and Molecular Biology and Associate Professor of Medicine at Mayo Clinic. He directs the Zebrafish Genetics Laboratory, focusing on cardiac diseases using zebrafish and African turquoise killifish models. His research elucidates molecular mechanisms of cardiomyopathy and develops therapeutic strategies, with a focus on genetic modifiers and precision medicine. Education : PhD: Developmental Genetics, Brookdale Center for Developmental & Molecular Biology, Mount Sinai Medical Center MS: Genetics, Institute of Genetics, Fudan University BS: Genetics, Department of Genetics & Genetic Engineering, Fudan University Research Interests : Genetic modifiers of cardiomyopathy, zebrafish genetics, precision medicine for heart diseases, cardiac aging, and translational therapeutic strategies. His lab employs mutagenesis screens and genome editing to identify novel genes and pathways. Recent Trends in Publications : Recent work emphasizes F0-based genetic assays for modifier gene discovery, electrophysiological techniques in zebrafish, and mechanisms linking diabetes to atrial fibrillation. Studies also target ADPKD and sarcomere-based cardiac diseases using zebrafish models. Awards & Editorial Roles : Innovation Accelerator Award (2024) Editorial Board Member: Frontiers in Physiology, JACC: Asia, PLOS One Fellow, American Heart Association Grants & Collaborations : NIH-funded studies on epicardial remodeling and sarcomere-based diseases Mayo Clinic Translational PKD Center collaborations Labs & Affiliations : Zebrafish Genetics Laboratory (Mayo Clinic) Co-leader, Cardiovascular Program at Kogod Center on Aging Affiliated with Mayo’s Department of Cardiovascular Medicine

Darren Creekمشاهده پروفایل

استاد

• Metabolomics
• Systems Pharmacology
• Parasitology
• +۷ مورد دیگر

Dr. Darren Creek is a Professor and ARC Future Fellow at Monash University's Faculty of Pharmacy and Pharmaceutical Sciences, Department of Drug Delivery, Disposition & Dynamics. His research focuses on metabolomics and systems pharmacology to combat infectious diseases like malaria and sleeping sickness. He holds leadership roles in major projects, including the 'Molecular Basis of Rapid Cellular Replication in the Malaria Parasite' (ARC-funded) and the 'Drug Target Identification Platform' (Department of Health & Aged Care). His work has led to novel metabolomics techniques and insights into protozoan parasite metabolism. Education: PhD in Pharmaceutics from Monash University (MIPS) under Professors Sue and Bill Charman. Postdoctoral experience includes preclinical drug discovery at Monash and parasite biochemistry at the University of Glasgow. Research Interests: Metabolomics, systems pharmacology, parasitology (malaria, trypanosomiasis), drug discovery, and antimicrobial resistance. Key achievements include co-developing IDEOM software for metabolomics and contributing to the Scottish Metabolomics Facility. Grants & Awards: ARC Future Fellow, Australian Synchrotron Award (2021), Monash Faculty Seed Grant (2017). Active in global health initiatives, including Uganda's orphan education and community health programs (Let the Needy Smile). Labs & Teams: Creek Lab (www.creek-lab.com), leading interdisciplinary teams in drug discovery and metabolic studies. Collaborations span Australia, UK, and international institutions.

James Murrayمشاهده پروفایل

مدرس ارشد

• Autophagy
• Aging Mechanisms
• Cell Signaling
• +۵ مورد دیگر

Dr. James Murray is a Senior Lecturer in Biomedical Sciences at Swansea University Medical School, specializing in aging mechanisms and age-related diseases. He leads research on autophagy pathways using the African Turquoise Killifish as a model organism. His work focuses on understanding tissue degeneration and developing drug targets for conditions like Alzheimer's and diabetes. Education & Research: His expertise spans molecular immunology, cell signaling, and drug discovery. He investigates cellular processes such as autophagy regulation, metabolic transformations in cancer, and the role of kinases like mTOR and SGK1. Research Trends: His publications emphasize autophagy mechanisms, aging-related pathologies, and cancer biology. Recent studies include optimizing mitochondrial analysis workflows for muscle biopsies and exploring plasma therapy for glioblastoma. Grants & Advising: Supervises PhD and MSc students on topics like Alzheimer's disease modeling and aging gene expression. Collaborates on projects funded by Swansea University and international consortia. Labs & Teams: Based at the Institute of Life Science, he contributes to interdisciplinary teams studying aging and translational medicine.