Yuchen Feng

Dr Yuchen Feng is a Lecturer (Research and Teaching) in the School of Medical Sciences at the University of Sydney's Faculty of Medicine and Health. They are a member of the Charles Perkins Centre and actively involved in cancer research, focusing on the roles of long noncoding RNAs (lncRNAs) in tumorigenesis and drug resistance. Their work integrates molecular oncology, RNA biology, and computational approaches to develop novel therapeutic strategies.

Research Interests: Dr Feng's lab explores mechanisms of cancer cell survival and metastasis, particularly through lncRNA-mediated regulation of DNA repair pathways, metabolic reprogramming, and interactions with tumor microenvironments. Key areas include noncoding RNA networks in p53/c-Myc signaling, translational control of oncogenes, and drug-resistant cancer cell subpopulations.

Grants & Funding: Recent grants include a 2025 NHMRC Investigator Grant for lncRNA-targeted lung cancer therapies and a 2024 Faculty of Medicine & Health start-up grant. Their research also received support from Tour de Cure Ltd for studies on drug-tolerant glioblastoma cells.

Advising & Lab: Dr Feng currently supervises Emma KEMPE in a project targeting glioblastoma drug resistance. Their team collaborates on multi-omics approaches to identify actionable targets in solid tumors.

Labs/Teams: Active member of the Charles Perkins Centre's Cancer Theme, contributing to interdisciplinary cancer research initiatives.