معرفی
Xin Li is an Associate Research Scientist at the Department of Cardiovascular Medicine, Yale School of Medicine. Their research focuses on vascular biology, molecular mechanisms of aortic diseases, and translational therapies. They investigate signaling pathways like TGF-β and mTOR, with applications in atherosclerosis, aneurysms, and tissue engineering. Li’s work integrates genetic models, ex vivo systems, and biomaterials to address clinical challenges in vascular medicine.
Key research interests include understanding mechanical homeostasis in arteries, developing xenogeneic-free vascular grafts, and exploring therapeutic targets for hypertension-induced aortic dissection. Their studies often involve interdisciplinary approaches, combining cell biology, genomics, and biomechanical analysis.
Recent publications highlight advancements in mTOR inhibition strategies for aneurysm treatment, melatonin’s protective role in nicotine-related vascular damage, and the use of CRISPR-engineered endothelial cells to evade immune rejection. Li collaborates across departments at Yale, including Internal Medicine and Biomedical Engineering, to translate findings into clinical applications.
No scientific awards are explicitly listed in the provided texts. Advising roles and grant details are not detailed here, though their extensive publication record suggests active research funding. Li contributes to lab initiatives focused on vascular regeneration and precision medicine in cardiovascular diseases.