معرفی
Mean Ghim is an Associate Research Scientist in the Department of Cardiovascular Medicine at Yale School of Medicine, affiliated with the Sadeghi Lab. His research focuses on molecular imaging of vascular pathologies and mechanobiological effects on endothelial cells, with a particular emphasis on collagen turnover, aortic valve disease, and inflammatory responses to disturbed flow.
- Education: Ph.D. in Biomedical Engineering
Research interests include molecular imaging techniques (e.g., PET/CT), endothelial mechanotransduction, and translational applications of collagen hybridizing peptides. His work bridges cardiovascular biology with engineering approaches to study disease mechanisms such as atherosclerosis, pulmonary fibrosis, and abdominal aortic aneurysm.
Recent studies highlight his contributions to understanding how disturbed flow induces inflammation through Wnt/β-catenin pathways and the development of radiotracers for collagen turnover imaging. Collaborations with Mehran Sadeghi, Gunjan Kukreja, and others underscore his interdisciplinary approach.
Publications emphasize molecular imaging innovations and mechanistic insights into vascular diseases, with a focus on translational applications.
