معرفی
Yibing Qyang is a Professor of Medicine (Cardiovascular Medicine) at Yale University School of Medicine (YSM), affiliated with the Department of Internal Medicine. He serves as Director of the Yale Stem Cell Research Forum since 2010. His expertise spans stem cell biology, cardiovascular disease modeling, and regenerative medicine. Qyang holds a B.S. from Nanjing University, an M.S. from Chinese Academy of Sciences, and a Ph.D. from the University of Texas M.D. Anderson Cancer Center. He completed postdoctoral training at UC San Diego and Harvard Medical School.
Research Interests: The Qyang Lab focuses on engineering vascular tissues using induced pluripotent stem cells (iPSCs), elucidating cardiovascular disease mechanisms, and developing therapeutic strategies. Key areas include:
- Vascular tissue engineering for graft development
- Stem cell-derived models of diseases like supravalvular aortic stenosis
- Cardiac progenitor cell therapies for heart repair
- Biomechanical signaling in hypertrophic cardiomyopathy
- Preclinical porcine models for translational research
Key Achievements:
- Developed immunocompatible 'universal donor' vascular grafts using CRISPR-engineered iPSCs
- Pioneered iPSC-derived vascular smooth muscle and endothelial cells for tissue engineering
- Identified elastin-based therapies for supravalvular aortic stenosis
Grants & Awards:
- Connecticut Stem Cell Program Established Investigator Awards (2011, 2015)
- ISSCR Membership (2007–Present)
- Highlighted in Yale News for groundbreaking discoveries in heart disease and vascular grafts
Lab Team & Collaborations: The lab includes researchers and students from institutions worldwide, with collaborations at Harvard, UCSD, and Yale’s Cardiovascular Research Center. Projects span iPSC differentiation, biomechanical modeling, and preclinical trials.
Future Directions: Expanding studies on universal donor grafts, cardiac tissue engineering, and clinical translation of iPSC-derived therapies.