معرفی
Yan Huang is an Associate Research Scientist in the Department of Comparative Medicine at Yale University's School of Medicine. He holds a PhD in Medicine from Hunan Medical University (1998) and has focused his research on cardiovascular diseases, stem cell biology, and regenerative medicine. His work includes developing transgene-free induced pluripotent stem cell (iPSC) models for vascular tissue engineering and exploring mechanisms underlying cardiac pathologies like supravalvular aortic stenosis and heart failure. Collaborations with researchers like Yibing Qyang and George Tellides highlight his team-based approach to translational research.
Key research themes include vascular endothelial cell engineering, elastin assembly in cardiovascular tissues, and molecular pathways regulating cardiac hypertrophy. Huang's contributions span peer-reviewed articles in high-impact journals such as Acta Biomaterialia and Arteriosclerosis Thrombosis and Vascular Biology. His publications emphasize translational applications, including therapeutic cell patches for heart disease and zinc-finger protein-based gene therapies.
No awards or grants are explicitly listed, but his work has been supported by funding such as a $2M federal grant for stem cell-based therapies (2019). He collaborates with interdisciplinary teams across cardiology, bioengineering, and molecular biology, contributing to both basic science and clinical applications in regenerative medicine.
