Xiaodi Wu

Xiaodi Wu is an Instructor in the Department of Medicine at Memorial Sloan Kettering Cancer Center (MSK), with involvement in the Hematology-Oncology program and Graduate Medical Education (GME). The research is centered at MSK, a leading institution in cancer research and treatment.

The research interests focus on the molecular mechanisms of hematologic malignancies, particularly in the context of clonal hematopoiesis and cancer genomics. Using advanced techniques like CRISPR dependency screens, the work aims to identify genotype-specific vulnerabilities in mutant cells, especially those with IDH2 and TET2 mutations. This research has direct implications for targeted therapies in leukemia and related disorders.

The recent publications indicate a strong focus on functional genomics in hematopoietic stem cells and the characterization of high-risk clonal genotypes in cancer patients. The work bridges basic science and clinical oncology, contributing to precision medicine approaches in hematologic diseases.

Scientific Awards:

• No awards listed in the provided text.

Xiaodi Wu is actively involved in collaborative cancer research at MSK, contributing to high-impact studies in oncology and hematology. While no specific grants or advising roles are mentioned, the co-authorship on significant journal articles suggests engagement in funded research projects and scientific mentorship within a large team environment.

Research is conducted within the Department of Medicine at MSK, likely as part of the Center for Hematologic Malignancies or a related research group, working in collaboration with prominent investigators in the field.