Ross L. Levine

Ross L. Levine is a Professor of Medicine at Weill Cornell Medical College, specializing in hematologic malignancies with a focus on acute myeloid leukemia (AML) and myeloproliferative neoplasms (MPNs). His research integrates genomics, epigenetics, and stem cell biology to unravel mechanisms driving clonal evolution and therapeutic resistance.

• Affiliation: Weill Cornell Medical College (2015–present)
• Research Themes: Mutation order in AML, epigenetic dysregulation, JAK-STAT pathway activation, sphingolipid metabolism in leukemia, and clonal hematopoiesis in aging/cardiovascular disease.

Recent publications highlight his work on:

• 2024 ELN risk stratification for AML patients
• CRISPR screens identifying genotype-specific vulnerabilities
• Multiomic survival predictors in African American AML patients
• Senolytic CAR T cells for age-related metabolic dysfunction

His studies span functional genomics, drug development, and clinical implementation of genomic profiling, with a strong emphasis on precision medicine applications in hematologic cancers.