معرفی
Professor Tony Green is a leading academic at the University of Cambridge, affiliated with the Cambridge Stem Cell Institute and the Department of Haematology. His research focuses on the molecular mechanisms underlying haematopoiesis and haematological malignancies, particularly the role of JAK/STAT signaling in myeloproliferative neoplasms (MPNs).
- Education: Medicine (University of Cambridge, University College Hospital London), PhD in oncogenic retroviruses (ICRF, London 1987)
- Academic Leadership: Professor of Haemato-oncology since 1999, Head of Haematology Department (2000-2020), Director of Cambridge Stem Cell Institute (2016-2022)
His research explores how blood stem cells become dysregulated in cancers like MPNs, with key findings on mutation order effects, non-canonical JAK/STAT signaling, and somatic mutation tracing in human hematopoiesis. His work bridges basic science, translational research, and clinical practice, with discoveries that transformed MPN diagnosis and JAK inhibitor development.
Scientific recognition includes:
- Jean Bernard Award (European Haematology Association, 2020)
- Donald Metcalf Award (International Society for Experimental Hematology, 2021)
His laboratory at the Jeffrey Cheah Biomedical Centre has produced seminal work on MPN mutational landscapes and stem cell fate regulation. Current research continues to investigate stem cell reprogramming in leukemogenesis.
