معرفی
Weiwei Yu is an Associate Research Scientist at the Chen Lab within the Yale School of Medicine. His research focuses on immunology and cancer biology, particularly exploring T cell dynamics, immune checkpoint pathways (B7-H1/PD-L1 and PD-L2), and tumor microenvironment interactions. Collaborating with prominent scientists like Lieping Chen, his work has advanced understanding of T cell quiescence mechanisms, immunotherapy resistance, and molecular mechanisms regulating anti-tumor immunity.
Key research areas include:
- Role of PLA2G10 in T cell infiltration suppression
- CD8α-PILRα signaling in maintaining T cell dormancy
- B7 family proteins in immune regulation
- Molecular pathways governing dendritic cell survival
Notable contributions include 2024 Science Immunology work on cancer immune evasion and 2022 Science findings on T cell quiescence. His studies bridge fundamental immunology with translational cancer research.
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