معرفی
Miguel López de Rodas Gregorio is an Associate Research Scientist in the Department of Pathology at Yale School of Medicine. He holds a Medical Doctorate from the University of Castilla-La Mancha. His research focuses on tumor immunology, immune checkpoint inhibitors, and translational oncology with particular emphasis on understanding T cell exhaustion mechanisms and spatial immune heterogeneity in cancer therapy response.
Key research areas include analyzing tumor-infiltrating lymphocytes' roles in PD-1/PD-L1 blockade efficacy, epigenetic regulation of tumor immunogenicity, and identifying novel therapeutic targets through transcriptomic and proteomic profiling. He collaborates with prominent investigators like Dr. Roy Herbst and Dr. Kurt Schalper.
His work bridges basic science and clinical applications, contributing to biomarker development for immunotherapy. Though no formal awards are listed, his publications in high-impact journals like Nature Reviews Clinical Oncology and Journal for ImmunoTherapy of Cancer demonstrate scholarly impact.
Gregorio's research group investigates mechanisms underlying immune evasion in solid tumors, with projects spanning lung, breast, and ovarian cancers. He contributes to Yale's translational research initiatives focused on systems immunology and precision oncology.
