معرفی
Wei Dai is a Professor at NYU Grossman School of Medicine, with joint appointments in the Department of Medicine and Department of Biochemistry and Molecular Pharmacology. His research focuses on the molecular mechanisms underlying cancer development and progression, particularly involving cell cycle regulation, genomic instability, and environmental toxicants.
- Education: PhD from Purdue University
Dr. Dai's research spans critical areas in cancer biology and toxicology. His work investigates:
- Cell cycle checkpoint control and mitotic regulation
- Genomic instability in carcinogenesis
- Aryl hydrocarbon receptor (AhR) signaling in oxidative stress and ferroptosis
- Environmental factors (heavy metals, toxicants) in cancer development
- Immune checkpoint modulation by stress pathways
- MicroRNA-gene interactions in environmental carcinogenesis
Recent publications highlight his contributions to understanding:
- EZH2's non-enzymatic role in cell cycle progression
- AhR-SLC7A11 axis in ferroptosis regulation
- KRas signaling in IDO1 expression and tumor immunity
- Metal-induced oxidative stress in epithelial-mesenchymal transition (EMT)
- Environmental toxicant impacts on immune checkpoint genes
- Structural characterization of SARS-CoV-2 spike protein epitopes
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