معرفی
Dr. Tony Jackson is a Professor at the University of Cambridge, serving as Director of Studies and Governing Body Fellow within the Department of Biochemistry in the School of Clinical Medicine. His research focuses on the structural and functional aspects of voltage-gated sodium channels, particularly examining the role of beta subunits in channel regulation and organization.
Dr. Jackson's primary research interests include sodium channel structure and function, protein-protein interactions, molecular mechanisms of cardiac and neuronal excitability, and the structural basis of channelopathies. His work has significantly advanced understanding of how beta subunits influence sodium channel assembly, trafficking, and function through detailed structural analyses and functional studies.
His publication record demonstrates consistent contributions to the field of ion channel research, with a particular emphasis on the structural organization of beta subunits, their role in channel clustering, and implications for cardiac and neuronal function. Recent work has explored the trimeric assembly of beta3 subunits and their impact on sodium channel organization in cellular membranes.
Dr. Jackson's research employs a multidisciplinary approach combining X-ray crystallography, atomic force microscopy, fluorescence photoactivated localization microscopy, and electrophysiological techniques to investigate sodium channel structure-function relationships at molecular and cellular levels.
