Mohamed Chahine

Mohamed Chahine, Ph.D., is a Full Professor in the Department of Medicine at Laval University and a key researcher at the CERVO Brain Research Centre. His work bridges cellular biophysics with clinical applications in cardiology and neuroscience.

• Education: Ph.D. in Cardiac Cellular and Molecular Biology (1987)
• Specializations: Ion channelopathies, patch clamp electrophysiology, hiPSC modeling

Dr. Chahine’s research focuses on the structure-function relationships of voltage-gated sodium channels in the brain and heart. His work has elucidated their roles in chronic pain syndromes, epilepsy, and cardiac arrhythmias, while exploring novel therapeutic targets through:

• Drug interaction studies with sodium channel blockers
• Gene editing and atomic force microscopy
• Patient-specific stem cell models

Article trends highlight expertise in:

• hiPSC-derived cardiomyocyte modeling
• Computational analysis of channel mutations
• Environmental toxin impacts on neural channels

Scientific contributions include:

• Heart and Stroke Foundation of Canada Research Scholar (1995-2000)
• Senior Investigator, Joseph C. Edwards Foundation (1999-2010)
• International collaborations in Japan, France, and China

His laboratory utilizes advanced methodologies like cut-open oocyte recordings and 3D forebrain organoids to investigate channelopathies, with recent projects addressing racial disparities in sudden cardiac death and anticonvulsant mechanisms.