Chai-Ann Ng

Dr. Chai-Ann Ng is a researcher at the Victor Chang Cardiac Research Institute and a member of the ClinGen Variant Curation Expert Panel for cardiac ion channels. His work focuses on functional interpretation of variants in cardiac potassium, sodium, and calcium channels, advancing precision medicine for cardiac channelopathies.

Education

• PhD

Research Interests

Dr. Ng specializes in:

• Developing validated high-throughput functional genomics assays for ion channel variants
• Distinguishing pathogenic from benign variants in long QT syndrome
• Reclassifying Variants of Uncertain Significance (VUS) for clinical decision-making
• Improving risk stratification and guiding interventions like implantable cardioverter-defibrillators

His research combines patch clamp electrophysiology with precision medicine to enable targeted pharmacotherapy and reduce sudden cardiac death risks.

Scientific Awards

• 2013 Young Biophysicist of the Year (Australian Society for Biophysics)
• 2024 ACvA Excellence in Cardiovascular Research Awards Finalist (Game Changer Award)

Grants

• 2021 MRFF Genomics Health Futures Mission Grant ($2.9m)
• 2024 UNSW CVMM Theme Collaborative Grant Scheme ($30k)