Tina Izard

Tina Izard, Ph.D., is a Professor in the Department of Chemistry at The Scripps Research Institute in Jupiter, Florida, leading the SR-CHEM-IZARD LAB. Her laboratory operates a cryoARM300 electron microscope installed in 2020, supporting high-resolution structural investigations of biological macromolecules central to infectious disease and environmental health research.

Her research program integrates Structural Biology, Biochemistry, and Toxicology to elucidate molecular mechanisms in disease pathogenesis. Key focus areas include protein structural dynamics (particularly enzymatic systems in tuberculosis), integrin-mediated cell signaling, and the disruptive effects of environmental toxicants on membrane microdomains. This work bridges atomic-level structural insights with cellular pathophysiology through advanced cryoEM methodologies.

Recent 2025 publications demonstrate dual research trajectories: structural enzymology of mycobacterial proteins revealing novel regulatory mechanisms, and toxicological studies showing how environmental agents impair integrin function in lipid rafts. Both strands emphasize molecular-scale understanding of disease processes with implications for therapeutic development.

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The SR-CHEM-IZARD LAB constitutes a specialized structural biology facility centered around the cryoARM300 platform, enabling near-atomic resolution imaging of protein complexes relevant to infectious disease and environmental toxicology. The laboratory operates within Scripps Research's chemistry infrastructure to advance mechanistic understanding of macromolecular systems.