Cornelius Gati

Cornelius Gati is an Assistant Professor at the University of Southern California, holding joint appointments in the Departments of Biological Sciences, Chemistry, Quantitative and Computational Biology, and Pharmacology and Pharmaceutical Sciences. His research focuses on structural pharmacology in neurotransmission and immunology, utilizing single-particle cryoEM and X-ray crystallography to determine atomic-scale structures of membrane proteins, particularly G protein-coupled receptors (GPCRs).

• Education: Ph.D. in Chemistry from DESY (2015), M.S. in Biology from Technical University of Munich (2012), B.Sc. in Biology from University of Tuebingen (2010)
• Postdoctoral Training: Stanford University (2017-2018), MRC Laboratory of Molecular Biology (2016-2017)

Research Interests include:

• Structural characterization of GPCRs and neurotransmitter transporters
• Elucidating mechanisms of synaptic transmission and immune receptor signaling
• Developing XFEL and cryoEM techniques for high-resolution protein structure determination

Recent publications highlight his work on:

• Biased signaling in complement receptors (2023 Cell collaboration)
• Structural basis of GABA transporter inhibition
• Mechanistic studies of opioid receptor activation
• Advanced XFEL and cryoEM methods for membrane protein analysis

Contact: gati@usc.edu | Office: MCB 351 | Twitter: @CorneliusGati