Selina Kathleen Jorch

Prof. Dr. Selina Kathleen Jorch serves as a Professor in the Department of Anaesthesiology, Intensive Care and Pain Therapy at the University of Münster. She actively contributes to the Multiscale Imaging Centre as a member of its Management & Communication committee, driving collaborative research in advanced imaging technologies and inflammatory disease mechanisms.

Her research program centers on immunological processes in sterile and infectious inflammation, with particular expertise in alarmin biology (S100A8/A9, MRP8/14), macrophage trafficking, and neutrophil extracellular traps. She pioneers intravital imaging approaches to visualize real-time immune dynamics in organ-specific contexts, investigating conditions ranging from sepsis and graft-versus-host disease to autoinflammatory disorders like Familial Mediterranean Fever. Her work bridges molecular mechanisms with translational applications, including peptide-based drug delivery systems for brain tumors.

Analysis of her 15 most recent publications reveals consistent focus on Gasdermin-D-mediated alarmin secretion pathways (2022-2023), GATA6+ macrophage functions in bacterial dissemination and cardiac repair (2019), and chemokine axis regulation in inflammatory diseases (2024). The research demonstrates strong interdisciplinary integration of molecular immunology, advanced microscopy, and clinical pathophysiology with implications for novel therapeutic interventions.

Prof. Jorch operates within the Multiscale Imaging Centre ecosystem, which provides cutting-edge microscopy resources and supports career development through Train Gain fellowships, travel awards, and graduate programs. The center facilitates collaborative projects across participating institutions while advancing women in science initiatives and hosting specialized seminars like the Inflammation & Imaging Lecture series.