معرفی
Scott M. Gordon, PhD is an Associate Professor at the University of Kentucky College of Medicine with appointments in the Physiology Department, Saha Cardiovascular Research Center, and Nutritional Sciences Graduate Program. His research focuses on metabolism and atherosclerotic cardiovascular disease through two primary investigative pathways.
His laboratory investigates mechanisms regulating dietary fat absorption by the intestine, including genes controlling chylomicron secretion and how fat absorption influences body weight, metabolism, and atherosclerosis. The second major research focus examines inflammatory protease activity in the artery wall and its suppression by lipoproteins, exploring natural inflammatory regulation mechanisms involving lipoproteins and developing lipoprotein-targeting protease inhibitors.
Analysis of his 15 most recent publications reveals a strong emphasis on HDL proteomics, cardiovascular risk prediction, and therapeutic interventions for atherosclerosis. His work spans from basic molecular mechanisms to clinical applications, with particular attention to how lipoprotein composition affects cardiovascular health. Recent studies have expanded into areas including neurodegenerative disease connections, asthma-related inflammation, and developmental origins of cardiovascular disease.
Dr. Gordon employs a sophisticated array of research techniques including mouse models for atherosclerosis and intestinal lipid absorption studies, genetically altered cell lines, CRISPR genetic manipulation, confocal and electron microscopy, molecular biology techniques, next-generation sequencing, and advanced proteomics and mass spectrometry approaches.
His educational background includes a PhD in Pathobiology and Molecular Medicine from the University of Cincinnati College of Medicine and a postdoctoral fellowship at the National Institutes of Health, NHLBI, building on his undergraduate foundation in Biological Sciences (with Chemistry minor) from the State University of New York College at Brockport.
