معرفی
Satish Khurana is an Associate Professor at the School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram (IISER TVM), where he leads research as a DBT-Wellcome Trust India Alliance fellow. His work focuses on the molecular regulation of hematopoietic stem cells (HSCs) and neural stem cells (NSCs), integrating metabolic pathways, integrin signaling, and niche architecture into his studies.
- B.Sc., M.Sc., and Ph.D. from Kurukshetra University, University of Delhi, and National Institute of Immunology, respectively.
- Postdoctoral experience at the Stem Cell Institute, KU Leuven, Belgium (2009-2015), supported by an FWO fellowship.
Khurana’s research investigates how metabolic profiles and integrin signaling govern HSC emergence in the embryonic aorta, expansion in fetal liver, and maintenance in adult niches like bone marrow and spleen. He also explores oxygen-sensing pathways in neurogenesis and their implications for hippocampal and sub-ventricular zone NSCs. His work bridges developmental biology with regenerative medicine, emphasizing physiological states like pregnancy and aging.
Recent publications highlight his lab’s contributions to understanding HSC niche dynamics in fetal liver and spleen, metabolic regulation of stem cell function, and integrin-mediated signaling in steady-state hematopoiesis. Collaborative studies extend to nanozyme development for cancer therapy and CRISPR-based gene editing in stem cell research.
Scientific Awards:
- DBT-Wellcome Trust India Alliance fellow
Khurana’s lab mentors a diverse cohort of PhD, BSMS, and MS students, many of whom have transitioned to advanced studies abroad or research roles in stem cell institutes. His team leverages mouse models and metabolic profiling to dissect mechanisms of stem cell quiescence, aging, and functional excellence.
