معرفی
Xing Feng is an Associate Research Scientist at the Yale School of Medicine, Yale University, specializing in hematopoiesis and stem cell biology. His work focuses on understanding interactions between hematopoietic stem/progenitor cells, leukemic cells, and mesenchymal stem cells (MSCs) in regulating blood cell development and cancer pathogenesis. Key research areas include fetal liver hematopoietic niches, signaling pathways in leukemia progression, and mechanisms governing emergency myelopoiesis.
- Research Highlights:
- Elucidated MSC-leukemia cell circuits blocking lymphopoiesis via lymphotoxin beta receptor signaling
- Discovered B cell-MSC regulatory networks controlling stress-induced myelopoiesis
- Characterized competitive interactions between hematopoietic stem/progenitor cells influencing stem cell compartment size
His collaborative projects involve interdisciplinary teams at Yale and international institutions, leveraging experimental models and spatial biology approaches to study hematopoietic systems. Current work aims to translate mechanistic insights into therapeutic strategies for blood cancers and hematologic disorders.
