معرفی
Sandra L. Pfister is a Professor in the Department of Pharmacology and Toxicology at the Medical College of Wisconsin. Her research focuses on cardiovascular pharmacology, particularly sex-based differences in pulmonary arterial hypertension (PAH) and the role of arachidonic acid metabolites like 15-HETE. She also specializes in medical education and has leadership roles such as Chair Emeritus of the Council for Women's Advocacy and Course Director for the MCWfusion Cardiovascular Block.
Education:
- PhD in Pharmacology, University of Texas Health Science Center, 1984
- BS from St. Mary's University, San Antonio, TX, 1978
Research Interests: Dr. Pfister investigates mechanisms underlying female predominance in PAH, including estrogen modulation of 15-lipoxygenase (15-LO) and 15-HETE-mediated vasoconstriction. Her work also explores thromboxane receptors' roles in atherosclerosis, distinguishing vascular vs. platelet receptor contributions to plaque formation. She employs rabbit and murine models to study these pathways.
Publications: Her recent work spans cellular metabolism of substance P, medical curriculum audits on sex/gender topics, and molecular mechanisms of vascular contraction/relaxation. These studies highlight interdisciplinary approaches linking basic science to clinical implications.
Awards: No scientific awards explicitly listed in the text.
Advising & Grants: While no student advisees are listed, Dr. Pfister's leadership roles reflect her commitment to institutional advocacy and curriculum development. Her research is funded through projects exploring estrogen-15-LO interactions and thromboxane receptor pharmacology.
Labs/Teams: Her laboratory focuses on vascular pharmacology, with collaborative projects involving cardiothoracic and immunology teams at MCW.
