معرفی
Victor G. Garcia, Ph.D. is an Associate Professor of Pharmacology at the School of Medicine, New York Medical College. His research program focuses on the molecular mechanisms of 20-hydroxyeicosatetraenoic acid (20-HETE) and its receptor GPR75, with implications for cardiovascular and metabolic diseases including hypertension, obesity, and liver disease.
Dr. Garcia received his Ph.D. in Pharmacology from New York Medical College in 2015, completed a postdoctoral fellowship in Pharmacology at Yale University, and holds an M.S. in Pharmacology from the University of Medicine and Dentistry of New Jersey and a B.A. in Biology from Drew University. His educational background provided a strong foundation in vascular biology and molecular pharmacology.
His primary research interests center on the 20-HETE/GPR75 signaling pathway, investigating how this vasoactive cytochrome P450-derived eicosanoid and its receptor contribute to hypertension, obesity, vascular dysfunction, and metabolic diseases. His laboratory work has demonstrated that GPR75-deficient mice are protected from high-fat diet-induced obesity and that understanding the 20-HETE/GPR75 pairing could lead to novel receptor blockers for treating chronic kidney disease, hypertension, heart failure, and obesity.
Analysis of Dr. Garcia's recent publications (2021-2024) reveals a strong focus on the CYP4/20-HETE/GPR75 axis, particularly its role in metabolic dysfunction-associated steatotic liver disease, obesity, hypertension, and cardiovascular diseases. His work bridges basic molecular mechanisms with translational applications, exploring both the fundamental biology of this signaling pathway and its therapeutic potential.
Dr. Garcia is an active member of the American Physiological Society (APS) and the American Heart Association (AHA), reflecting his contributions to cardiovascular and metabolic research.
While specific details about his mentoring activities are not provided in the available information, Dr. Garcia's extensive publication record, including numerous first-author and senior-author papers, suggests active involvement in training graduate students and postdoctoral researchers. His research program appears to be supported by grants focused on vascular biology and metabolic disease mechanisms.
Dr. Garcia leads a research laboratory investigating the molecular mechanisms of 20-HETE signaling, with a particular focus on the GPR75 receptor. His work involves collaborations with researchers across multiple institutions, as evidenced by his co-authorship on papers with scientists from various universities and research centers.
