جستجوی استاد راهنمای دانشگاهی

Professor Hutan Ashrafian is a clinician-scientist and surgeon at the University of Leeds Business School, holding dual roles as Professor of Research Impact and Senior Research Fellow at Imperial College London. His expertise spans AI in healthcare, metabolic surgery, and ancient history. He pioneered STARD-AI and QUADAS-AI guidelines for AI diagnostics, collaborated on AI-driven breast cancer screening with Google and NHS, and led global health policy initiatives. Ashrafian’s work bridges medicine, history, and philosophy, including his contributions to understanding historical figures’ medical conditions, such as King Tutankhamun’s epilepsy. He has authored over 550 publications, 12 books, and holds a PhD in computational physiology and an MBA with distinction. Awards include the Hunterian Prize and Wellcome Trust Fellowship. His research also explores AI ethics, quantum physics paradoxes, and art-based medical diagnostics. Education: PhD in Computational Physiology (Imperial College London) MBA (Warwick Business School) MD (University College London) Bachelor of Science in Immunology (University College London) Research Interests: Ashrafian’s work spans: AI in Medicine: Diagnostic algorithms, guideline development (STARD-AI/QUADAS-AI), and ethical frameworks. Metabolic Surgery: Bariatric interventions, gut microbiome, and obesity treatments. Ancient History: Medical analyses of historical figures (e.g., Tutankhamun, Julius Caesar) and art-based pathology identification. Philosophy: AI rights (AIONAI law), temporal paradoxes, and the Simulation Argument. Awards: Royal College of Surgeons Arris and Gale Lectureship Hunterian Prize Wellcome Trust Research Fellowship Advising & Innovation: Supervised >50 PhD students, co-founded Oxford Medical Products (weight loss tech), and serves as CSO at Flagship Pioneering’s Preemptive Health division. He advises on NHS digital transformation and global health policy. Labs/Teams: Leads AI initiatives at Imperial’s Institute of Global Health Innovation and collaborates with Google, NICE, and international institutions on health tech solutions.

• Artificial Intelligence in Medicine
• Metabolic Surgery
• Health Policy
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Professor Chris Holmes is a Professor of Biostatistics at the University of Oxford, where he moved from Imperial College London in February 2004. He is a Fellow at St Anne's College and works in the Department of Statistics. His research focuses on applications and statistical methods development in genomic sciences and genetic epidemiology, holding a prestigious Programme Leaders Grant in Statistical Genomics from the Medical Research Council. Prior to his position at Oxford, Professor Holmes completed his doctorate in Bayesian statistics at Imperial College London, investigating novel nonlinear pattern recognition methods. This was followed by a post-doctoral position and then a lectureship at Imperial. Before his academic career, he worked in industry for several years in scientific computing, developing techniques for real-time pattern recognition models in defense and SCADA systems. Professor Holmes has a broad interest in the theory, methods and applications of statistics and statistical modeling, with a particular foundation in Bayesian statistics which he views as providing a unified framework for stochastic modeling and information processing. His specific research interests include: Bayesian statistics and stochastic simulation Markov chain Monte Carlo methods Pattern recognition and nonlinear, nonparametric methods Spatial statistics Statistical genetics and genomics Genetic epidemiology His recent publications (2023-2025) demonstrate a strong focus on the intersection of biostatistics, artificial intelligence, and healthcare applications. His work spans multiple domains including AI-driven disease classification in neurology, genomic data analysis for health equity, machine learning tools for healthcare prediction, and addressing bias in medical AI systems. A notable trend across his research is the application of advanced statistical methods to solve pressing problems in genomics, epidemiology, and medical diagnostics, with an increasing emphasis on health equity and the ethical implications of AI in healthcare. Professor Holmes currently supervises PhD students Oscar Clivio, Sahra Ghalebikesabi, and Natalia Garcia Martin. His research is supported by multiple grants, including the MRC Programme Leaders Grant in Statistical Genomics which funds his work in statistical genomics. He is actively involved in three research groups at Oxford that reflect the breadth of his scholarly interests: Computational Statistics and Machine Learning Statistical Genetics and Epidemiology Statistical Theory and Methodology

• Bayesian statistics
• Stochastic simulation
• Markov chain Monte Carlo
• +۵ مورد دیگر

Daniel Finley is a Professor of Cell Biology at Harvard Medical School (HMS), leading the Finley Lab focused on the ubiquitin-proteasome pathway and related regulatory mechanisms. He holds academic appointments within the Department of Cell Biology and sits on the Scientific Advisory Boards of Proteostasis and X-Chem Pharmaceuticals. His research investigates proteasome function, ubiquitin-like proteins, and proteostasis roles in diseases like Alzheimer’s and ALS. Dr. Finley earned his undergraduate degree in biochemistry from Harvard University and a Ph.D. in molecular biology from MIT. After postdoctoral training at MIT, he joined HMS in 1988. His lab explores topics including erythroid proteome remodeling, mitochondrial dysfunction, and neurodegenerative disease mechanisms. Key research areas include: (1) Ubiquitin-proteasome pathway regulation, (2) Proteasome structure/function, (3) Nonproteolytic roles of ubiquitination, and (4) Pathophysiological roles of proteostasis defects in diseases. His work bridges basic cell biology with translational medicine, particularly in neurodegeneration and anemia. Finley has secured NIH funding for projects like 'Regulation of Proteasome Activity' (R35GM145246) and 'Erythrocyte maturation through global proteome remodeling' (R01HL153970). Collaborations with industry and academic partners extend his impact in drug discovery and proteasome-targeted therapies. His lab’s contributions include defining ubiquitin chain editing mechanisms, identifying USP14’s role in mitophagy, and elucidating proteostasis defects in Alzheimer's models. Research tools developed include advanced cryo-EM analyses of proteasomal structures and functional assays for ubiquitin system enzymes.

• Ubiquitin-Proteasome Pathway
• Proteostasis
• Protein Degradation
• +۷ مورد دیگر

Roles & Affiliations: Ikhlas Khan serves as Director of the National Center for Natural Products Research (NCNPR), Distinguished Professor, and Research Professor of Pharmacognosy at the University of Mississippi's School of Pharmacy. He also leads the FDA Program and coordinates natural products research across multiple initiatives, including the Sino-US TCM Research Center and the Center for Research of Indian Systems of Medicine (CRISM). Education: B.Sc. Chemistry (1980) - Aligarh Muslim University, India M.Sc. Organic Chemistry (1982) - Aligarh Muslim University, India Ph.D. Pharmacy (1987) - Ludwig-Maximilians-Universität, Munich Postdoctoral Studies - Swiss Federal Institute of Technology (ETH), Zurich Research Focus: Dr. Khan specializes in natural products research with emphasis on: Phytomedicine: Standardization of herbal products via analytical fingerprinting, pesticide/herbicide residue analysis, and bioanalytical quality control. Drug Discovery: Isolation of bioactive natural products, development of analytical methods for phytochemical characterization, and chiral separation techniques. Metabolism Studies: Role of metabolism in drug/natural product activity, particularly in aminoquinoline antimalarials. His work bridges academia, industry, and regulatory bodies, shaping policies for botanical supplements. Key Contributions: Over 850 peer-reviewed publications and leadership in high-impact projects like the FDA Center of Excellence. His lab pioneered methods to combat herbal product adulteration and safety issues. Awards & Recognition: UM Distinguished Professor Award (2018) Wiley Award (AOAC International, 2018) Qihuang International Prize (2017) Honoris Causa Doctorate (University of Hamdard, 2012) Labs & Collaborations: Directs the NCNPR, a global leader in natural products research, and collaborates with institutions worldwide. His team develops technologies for herbal product authentication and drug metabolism studies.

• Natural Products Research
• Phytomedicine
• Herbal Product Standardization
• +۷ مورد دیگر

Allison Ross Eckard, MD is Professor in the Departments of Pediatrics and Medicine at the Medical University of South Carolina (MUSC) College of Medicine, serving as Division Chief for Pediatric Infectious Diseases and Director of MUSC's Ryan White Pediatric HIV Clinic and HIV Transition Clinic. She maintains an adjunct faculty position at Emory University and holds board certification in Pediatrics and Pediatric Infectious Diseases. Her primary research focuses on metabolic, cardiovascular, and nutritional complications of chronic HIV and antiretroviral therapy across age groups, with emphasis on inflammation's role in comorbidities like cardiovascular disease and bone disorders. Current investigations include NIH R01-funded research on interventions for weight gain and abdominal fat in HIV, vitamin D supplementation, and statin therapy. She has published nearly 60 peer-reviewed papers on HIV pathogenesis and treatment optimization. Dr. Eckard co-chairs the DHHS panel for Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Exposed and HIV-Infected Children and serves on the DHHS panel for Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents with HIV . Her clinical work specializes in comprehensive HIV care for children through young adults, with particular focus on adolescent/young adult transition issues and global health initiatives through Lespwa Timoun in Haiti. Recent efforts include developing COVID-19 treatment guidelines for children and school safety protocols. HIV Specialist certification (American Academy of HIV Medicine) Fellow, Infectious Diseases Society of America Fellow, Pediatric Infectious Diseases Society Fellow, HIV Medical Association Member, HIV Medical Association's 'Ending the HIV Epidemic' working group She leads MUSC's HIV education initiatives and serves as inpatient consultant for pediatric infectious diseases, with advanced training in tropical medicine. Her NIH-funded research examines targeted interventions to minimize comorbidity development in HIV, while her clinical leadership spans the Ryan White HIV program, transition clinics, and global health partnerships.

• HIV-related cardiometabolic complications
• Antiretroviral therapy optimization
• Pediatric infectious diseases
• +۷ مورد دیگر

Yaojun Zhang is an Assistant Professor in the Department of Physics & Astronomy and the Department of Biophysics at Johns Hopkins University. She earned her PhD in Physics from the University of California, San Diego (2015), followed by postdoctoral fellowships at the Princeton Center for Theoretical Science (2015-2018) and the Princeton Center for the Physics of Biological Function (2018-2021). Her research focuses on biological physics, particularly the complex behaviors of biomolecules and their assemblies across scales—from single-molecule folding to intracellular transport and biomolecular phase separation. She employs theoretical, mathematical, and computational tools to bridge biological questions with physical principles. Education PhD in Physics, University of California, San Diego (2015) Postdoctoral Fellowships: Princeton University (2015-2021) Research Interests Her group studies biomolecular condensates and liquid-liquid phase separation, exploring how microscopic interactions determine macroscopic properties of cellular compartments. Key areas include: Biomolecular condensate formation and dynamics Phase separation in cellular environments Interactions between biomolecules and cellular components Biophysics of intracellular transport Collaborations & Tools Zhang collaborates with experimentalists to validate theoretical models and develops frameworks for understanding condensate functions, such as surface tension, stoichiometry, and phase diagrams. Her work addresses challenges like condensate stability, molecular exclusion, and biological function regulation. Labs & Resources She leads the Zhang Lab , which integrates experimental and computational approaches. Her team’s research is supported by resources at the Bloomberg Center for Physics and Astronomy.

• Biological Physics
• Biophysics
• Theoretical Physics
• +۳ مورد دیگر

Karen Piper Hanley is Professor of Molecular Medicine and Head of Division in the Division of Diabetes, Endocrinology & Gastroenterology at the University of Manchester. She serves as the fibrosis lead in the Wellcome Trust Centre for Cell-Matrix Research and previously served as Director of Core Research Technologies (2019-2022). She is also an editorial board member for Scientific Reports. Her research focuses on fibrosis (scarring) mechanisms across multiple organs, particularly liver, kidney, and lung fibrosis. Her lab investigates the cellular and molecular basis of fibrotic disease, with emphasis on how pathological scar components are produced and how they signal to surrounding cells. Key areas include the role of SOX9 transcription factor, integrin beta-1 signaling, Group 1 PAKs, and YAP1 in fibrosis progression. Her recent publications reveal trends toward increased clinical translation of fibrosis research, with studies on health inequalities in liver cancer care, post-COVID diabetes incidence, and innovative approaches to liver disease detection. Her work increasingly integrates spatial transcriptomics and advanced omics technologies to understand cellular transitions in liver disease. Career-track postdoctoral fellowship from the University of Southampton (2006) As senior postgraduate tutor, she has mentored numerous PhD students who have presented at key conferences and authored high-quality manuscripts. All her PhD students have submitted and been awarded their degrees within 4 years. She has successfully guided previous Academic Clinical Fellows to win MRC clinical training fellowships. Her teaching extends to undergraduate Personal & Professional Development and supervision of MRes and BSc students, many of whom have achieved first-class degrees and prestigious awards. Her lab maintains active collaborations with Professor Neil Hanley's group on human development, stem cells, and regenerative medicine, bridging developmental biology with fibrosis research to understand why regeneration is impaired in chronic diseases.

• Fibrosis Research
• Liver Fibrosis
• Kidney Fibrosis
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Andre Levchenko is the John C. Malone Professor of Biomedical Engineering at Yale University, with secondary appointments in the Department of Neurosurgery and affiliations with the Cancer Signaling Networks, Immunology, and the Yale Program in Neurodevelopment and Regeneration. His research focuses on systems biology, signal transduction, and cell-cell communication, utilizing microfluidics and computational modeling to study cancer progression, stem cell behavior, and neurological disorders. PhD, Columbia University MEng, Moscow Institute of Physics and Technology Levchenko's work explores how cells process dynamic signals to make critical decisions, particularly in glioblastoma migration, organoid development, and cardiovascular tissue engineering. His lab develops innovative microfluidic platforms and mathematical models to dissect multicellular communication and signaling networks. Recent publications highlight his contributions to understanding YAP-driven cancer invasion , NOTCH signaling in angiogenesis , and metabolic regulation of hypoxia responses . He has pioneered methods for organoid modeling and single-cell analysis , advancing precision in biological signaling studies. Scientific Awards : Computational Molecular Biology Post-Doctoral Fellowship (Burroughs Wellcome Fund) National Academies Keck Futures Conference Invitee Distinguished Guest Lecturer, University of Virginia American Asthma Foundation Early Excellence Award Fellow, American Institute for Medical and Biological Engineering Levchenko leads the Levchenko Lab at the Yale Systems Biology Institute, collaborating with institutions like Mayo Clinic and Yale Cancer Center. His research has received recognition in Faculty of 1000 and multiple journal highlights.

• Systems Biology
• Signal Transduction
• Cell Communication
• +۵ مورد دیگر

Dr. Giulia Biancon is an Assistant Professor Adjunct in the Department of Medical Oncology and Hematology at Yale School of Medicine. She holds a PhD from the University of Milan (2019) and is a member of the Halene Lab, focusing on RNA biology and hematologic malignancies. Her research combines high-throughput methodologies to study RNA mechanisms in diseases like myeloid leukemias and splicing factor mutations. Education: PhD in Molecular Biology from the University of Milan (2019). Research Interests: RNA splicing, stress granules in cancer, epitranscriptomics, clonal hematopoiesis, and the interplay between genetic mutations and cellular pathways in blood cancers. Awards: 2024 Eclipse Award, 2022 ASH Abstract Achievement Award, and 2022 RNA Society Best Poster Award. Her work has been published in journals like Cell Reports , Blood , and Molecular Cell . Labs/Teams: Principal member of the Halene Lab and coordinator at the Yale Center for RNA Science and Medicine. Collaborates with institutions like the SeroNet network for immunology studies.

• RNA Biology
• Myeloid Malignancies
• Hematology
• +۴ مورد دیگر

Zainab Taleb is affiliated with the University of Windsor, contributing to research in circadian biology and its implications for digestive health. Her work focuses on the interplay between circadian rhythms, intestinal stem cells, and disease mechanisms such as colitis and tumor initiation. She participated in a university panel addressing vaccine hesitancy related to the pandemic response. Research emphasizes circadian clock genes like BMAL1 and their role in metabolic and inflammatory processes. Collaborations may involve interdisciplinary teams studying chronobiology's impact on gastrointestinal disorders and oncology. Her studies utilize animal models to investigate timing-dependent physiological responses, with potential applications in therapeutic timing strategies.

• Circadian Biology
• Gastroenterology
• Metabolic Studies
• +۳ مورد دیگر

Kristian Helin is Chief Executive and President of The Institute of Cancer Research (ICR), London, and a Professor with affiliations at the University of Copenhagen and Memorial Sloan Kettering Cancer Center. He founded/directed the Biotech Research & Innovation Centre (BRIC), Centre for Epigenetics, and Danish Stem Cell Center. His research focuses on epigenetic regulation, cancer biology, and stem cell differentiation. Education: Ph.D. Molecular Biology, University of Copenhagen (1991) M.Sc. Chemical Engineering, Technical University of Denmark (1988) Research Interests: Helin's work deciphers molecular mechanisms in cancer, emphasizing epigenetic drivers (e.g., H3K4/H3K36 methylation), transcriptional control, and therapeutic targeting. His lab identified E2F transcription factors, linked epigenetic dysregulation to leukemia/lymphoma, and develops drugs targeting kinases/epigenetic enzymes. Research spans acute myeloid leukemia, B-cell lymphoma, and solid tumors using CRISPR screens and preclinical models. Publication Trends: Recent articles (2023-2025) focus on epigenetic therapy, chromatin remodeling, and kinase signaling in cancer. Key themes include targeting NSD1/KDM5C/RIOK2 enzymes, combination therapies (EZH2/DOT1L inhibitors), and metabolic regulation in leukemia. Studies bridge basic mechanisms (enhancer regulation, insulator accessibility) with translational applications. Awards: Anders Jahre Prize (2014), ERC Advanced Grant (2011), Novo Nordisk Prize (2008) Memberships: Academia Europaea, Royal Danish Academy, EMBO Leadership: Helin co-founded EpiTherapeutics (acquired by Gilead) and leads the Epigenetics and Cancer lab at ICR. His team investigates AML pathogenesis and chromatin complexes like HUSH/NURF. Grants include ERC funding and innovation prizes.

• Cancer biology
• Epigenetics
• Stem cells
• +۵ مورد دیگر

Thomas R Overton serves as Department Chair and Professor of Dairy Nutrition and Management in the Department of Animal Science at Cornell University's College of Agriculture and Life Sciences (CALS). He also directs PRO-DAIRY, an extension program focused on enhancing dairy farm profitability and efficiency in New York through research-based strategies for transition cow management. Education: Doctorate, University of Illinois, 1998 Master of Science, University of Illinois, 1994 Bachelor of Science, Cornell University, 1991 Dr. Overton's research centers on the transition period (late pregnancy to early lactation) in dairy cows—the most critical phase for health and productivity. His work integrates nutritional physiology with practical farm applications, targeting hypocalcemia management, protein supplementation strategies, inflammation control, and biomarker validation for metabolic health. This research directly informs his extension efforts through PRO-DAIRY, which delivers actionable knowledge to dairy producers and industry professionals. Analysis of his 15 most recent publications (2022-2024) reveals consistent emphasis on transition cow nutrition, with growing focus on metabolic analytics, precision feeding, and real-world herd management. His work bridges controlled studies at Cornell's Ruminant Center with observational research on commercial New York dairy farms. Scientific Awards: 2024 Nutrition Professionals Applied Dairy Research Award (American Dairy Science Association) 2010 CALS Extension/Outreach Team Award (PRO-DAIRY) 2007 Foundation Scholar Award (American Dairy Science Association) 2007 CALS Extension/Outreach Team Award Dr. Overton advises undergraduate and graduate students in Animal Science while leading PRO-DAIRY's extension initiatives. His program secures industry partnerships and grants focused on improving dairy farm sustainability through nutritional science. The July 2025 'Farm of the Future' showcase at Cornell's Ruminant Center exemplifies his commitment to translating research into practical innovation. He operates within Cornell's PRO-DAIRY program and the Cornell University Ruminant Center—a living laboratory for dairy technology testing—collaborating closely with industry stakeholders to address emerging challenges in dairy production.

• Dairy Cattle Nutrition
• Transition Cow Management
• Metabolic Health of Dairy Cows
• +۳ مورد دیگر

Mersema Abate, MD, MPH is an Associate Professor in the Department of Medicine and Science Education at the Zucker School of Medicine at Hofstra/Northwell. She also serves as Director of Advanced Clinical Experience at Northwell Health. Her research focuses on kidney transplantation outcomes, health disparities, and post-transplant glycemic control. She has published extensively on topics such as racial inequities in kidney transplant eligibility, electrolyte abnormalities in critically ill patients, and the impact of comorbidities on transplant success. Her work has been cited over 1,000 times, with notable contributions to understanding the role of race in clinical algorithms and managing infections in immunocompromised patients. Research Interests: Optimizing post-transplant metabolic control Addressing systemic disparities in organ transplantation Multimodal approaches to kidney failure management COVID-19's impact on renal and transplant medicine Publications: Her 70+ articles span peer-reviewed journals like Clinical Transplantation and Journal of the American Society of Nephrology , focusing on clinical nephrology and transplant medicine. Recent work emphasizes implementation of continuous glucose monitoring systems and re-evaluation of race-based clinical metrics. Grants/Advising: No formal grants or student advisees are currently listed in her profile.

• Nephrology
• Kidney Transplantation
• Transplant Medicine
• +۴ مورد دیگر

David H. Sherman is the Hans W. Vahlteich Professor of Medicinal Chemistry at the University of Michigan, holding joint appointments in the College of Pharmacy (Department of Medicinal Chemistry), Medical School (Microbiology & Immunology), and College of Literature, Science, and the Arts (Chemistry). He leads the Sherman Lab at the Life Sciences Institute and co-founded the Natural Products Discovery Core. His research focuses on natural product discovery, biosynthetic pathways, and drug development for infectious diseases, cancer, and neurological disorders. Education: PhD in Synthetic Organic Chemistry from Columbia University (1981), BA in Chemistry from UC Santa Cruz (1978). Postdoctoral research at MIT (1984). Research interests include microbial secondary metabolites, enzymatic catalysis (e.g., C-H functionalization, polyketide assembly), and high-throughput drug screening. He pioneered a microbial natural product library with over 50,000 samples. Current projects emphasize developing macrolide antibiotics and advancing compounds toward clinical trials through the Natural Products Biosciences Initiative. Collaborations span global institutions, with a focus on biodiversity conservation and capacity-building in low-income nations. He has mentored 67 PhD students, 60 postdocs, and 85+ undergraduates, fostering interdisciplinary training in chemical biology and microbial biochemistry. Labs/Teams: Sherman Lab (Life Sciences Institute), Center Member at Samuel and Jean Frankel Cardiovascular Center, Center for Computational Medicine and Bioinformatics, Rogel Cancer Center.

• Natural Products Chemistry
• Medicinal Chemistry
• Biosynthesis
• +۴ مورد دیگر

Anirban Paul is an Associate Professor in the Department of Neuroscience and Experimental Therapeutics at Pennsylvania State University, affiliated with the Penn State Neuroscience Institute. His research focuses on cellular and molecular mechanisms of GABAergic inhibitory circuits, with particular emphasis on interneuron biology and its implications in neurological disorders. Dr. Paul's research spans multiple neuroscience domains, with primary focus on GABAergic inhibitory circuits and interneuron biology. His work investigates how specific neuron subtypes, particularly Chandelier cells and cortical interneurons, contribute to brain function and dysfunction. He has made significant contributions to understanding the role of these cells in schizophrenia, Alzheimer's disease, and other neurological conditions. His research integrates molecular, cellular, and systems-level approaches to uncover fundamental mechanisms of neural circuit assembly, plasticity, and function. Key areas include RNA regulation in neuronal development, transcriptomic subtypes of inhibitory neurons, and cell-type specific vulnerabilities in neurodegenerative diseases. His research portfolio demonstrates consistent productivity with publications spanning from 2003 to 2025, showing an evolving focus from basic molecular neuroscience to translational research in neurological disorders. Recent work emphasizes single-cell analysis techniques and the role of specific interneuron populations in disease mechanisms, particularly in schizophrenia and Alzheimer's disease. His publications appear in high-impact neuroscience journals including Neuron, BMC Biology, and Frontiers in Cellular Neuroscience. Dr. Paul has received the NARSAD Young Investigator Award (2018), recognizing his promising research in neuroscience. His scientific contributions have been supported by multiple competitive grants from prestigious organizations including the National Institute on Aging (NIA) and the Brain and Behavior Research Foundation. He serves as Principal Investigator on multiple active research projects, including two major grants from the National Institute on Aging focused on cell-type specific risk and resilience in Alzheimer's disease and aging (2021-2024 and 2024-2026), as well as previous projects from the Brain and Behavior Research Foundation investigating Chandelier cells in schizophrenia. His research program demonstrates sustained funding and scientific leadership in the field of interneuron biology and its clinical implications.

• Neuroscience
• GABAergic inhibitory circuits
• Interneuron biology
• +۵ مورد دیگر