Samuel H. Gellman

Samuel H. Gellman is a Professor of Chemistry at the University of Wisconsin-Madison, holding the Irving Shain Chair and the Ralph F. Hirschmann Professorship. His research focuses on foldamer design, protein folding, GPCR signaling, and biopolymer assembly in condensed phases.

• Education: A.B. from Harvard (1981), Ph.D. from Columbia (1986), Postdoc at Caltech (1986-87)

Research spans asymmetric synthesis, NMR/crystallography, and biomedical applications like antiviral agents and cancer therapeutics. Recent publications highlight innovations in β-amino acid incorporation, biased agonism, and racemic crystallization techniques.

His scientific awards include the Vilas Research Professorship and Ralph F. Hirschmann Professor of Chemistry. The Gellman Group trains graduate students and postdocs in multidisciplinary approaches, mentoring former members now at Yale, Monash, and Bristol.

Current projects include foldamer catalysis, anti-viral peptides, and elucidating liquid-liquid phase separation mechanisms. Collaborations involve structural biology, molecular dynamics, and clinical applications.