معرفی
Ryan O’Dell, MD, PhD, is an Assistant Professor of Psychiatry at the Yale School of Medicine, specializing in geriatric psychiatry and Alzheimer’s disease research. He leads the Alzheimer’s Disease Research Unit (ADRU), focusing on neuroimaging biomarkers and clinical trials. His academic background includes an MD/PhD from SUNY Upstate Medical University and residency training at Yale. Dr. O’Dell’s research emphasizes synaptic density assessment via [11C]UCB-J PET and tau protein dynamics in Alzheimer’s progression.
- Affiliations: Yale School of Medicine, Dorothy Adler Geriatric Assessment Center
- Education: SUNY Upstate Medical University (MD/PhD, 2017), University of Rochester (BS/BA, 2007)
Research Interests: Molecular neuroimaging, clinical trial design, and translational studies targeting synaptic loss in Alzheimer’s. His work integrates PET, MRI, and clinical data to identify biomarkers for early diagnosis and therapeutic monitoring. Recent studies explore tau spreading mechanisms and disparities in cognitive impairment diagnosis among language groups.
Publications: Over 25 peer-reviewed articles focus on synaptic density, tau imaging, and clinical outcomes. Key themes include biomarker validation (e.g., SUVR metrics), tau connectivity patterns, and CT1812 drug trials.
- Awards: Paul Kirwin Distinguished Fellow Award (2022), Thomas P. Detre Fellowship (2019)
Clinical Work: Provides geriatric psychiatry care with a family-centered approach at the ADRU. Active in Yale’s Alzheimer’s clinical trials and lecanemab programs. Coordinates the ADRU’s caregiver support group.