معرفی
Ming-Kai Chen, MD, PhD is an Associate Professor in the Department of Radiology & Biomedical Imaging at Yale School of Medicine. He serves as Co-Medical Director of the Yale University PET Center and specializes in nuclear medicine and molecular imaging, particularly in synaptic density assessment for neurodegenerative diseases like Alzheimer’s. His research focuses on advancing PET imaging techniques for early disease detection and biomarker analysis, with a strong emphasis on synaptic vesicle glycoprotein 2A (SV2A) imaging.
Dr. Chen’s educational background includes an MD from National Taiwan University School of Medicine and a PhD from Johns Hopkins University. He completed residency at Yale New Haven Hospital and fellowships in nuclear medicine and radiology at Johns Hopkins Hospital.
His research interests span synaptic density imaging, Alzheimer’s disease biomarkers, and the application of artificial intelligence in PET image enhancement and analysis. Key projects include validating simplified SUVR measurements for synaptic density assessment and developing motion correction techniques for dynamic PET scans.
Dr. Chen collaborates with researchers like Richard Carson, Nabeel Nabulsi, and Jean-Dominique Gallezot on studies involving synaptic loss, tau deposition, and multimodal neuroimaging. His clinical trials include investigations into synaptic density in Alzheimer’s and the impact of nicotine patches on dopamine pathways.
He holds board certification in Nuclear Medicine from the American Board of Nuclear Medicine. His work has been featured in journals such as the Journal of Nuclear Medicine, Brain Communications, and Medical Image Analysis.