Reggie Bosma

Dr. Reggie Bosma is an Assistant Professor at the Faculty of Science, Department of Chemistry and Pharmaceutical Sciences, and affiliated with AIMMS (Amsterdam Institute for Molecular and Life Sciences) at Vrije Universiteit Amsterdam. His research focuses on pharmacology, molecular biology, and drug discovery, particularly targeting G-protein coupled receptors (GPCRs) such as histamine H1 receptors, chemokine receptors (e.g., CXCR4, ACKR3), and adrenergic receptors.

His work contributes to UN Sustainable Development Goals, emphasizing health and innovation. Key research areas include ligand binding kinetics, small molecule design, and optogenetic approaches for receptor modulation. He teaches courses like Innovatieproject geneesmiddelen and Tutoraat for pharmacy and biomedical students.

Recent studies explore inverse agonists for CXCR4 in myeloma treatment, photoswitchable beta blockers for in vivo control of adrenergic receptors, and conformational dynamics of chemokine receptors. Bosma has supervised a PhD thesis and collaborates internationally on receptor pharmacology and bioluminescence-based assays.