Claudia Victoria Perez Almeria

Claudia Victoria Perez Almeria serves as a Research Fellow at Vrije Universiteit Amsterdam's Faculty of Science within the Department of Chemistry and Pharmaceutical Sciences, with additional affiliation to AIMMS (Amsterdam Institute of Molecular and Life Sciences). Her ORCID profile (0000-0002-7312-8529) confirms her active research status through 2025 publications.

Her research focuses on G protein-coupled receptor (GPCR) mechanisms, particularly CXCR4 and ACKR3 chemokine receptors. Key areas include receptor oligomerization, nanobody-based modulation techniques, and the role of these processes in carcinogenesis. She has developed innovative methodological approaches combining nanobodies with NanoBRET technology for precise monitoring of membrane protein interactions.

Analysis of her recent publications reveals a cohesive research trajectory examining how receptor oligomerization and non-canonical signaling contribute to oncogenic processes in lymphoid neoplasms. Her work bridges molecular pharmacology with cancer biology, demonstrating how disruption of constitutive CXCR4 oligomers impairs oncogenic properties and how receptor C-termini regulate arrestin-mediated trafficking.

Dr. Perez Almeria's contributions advance understanding of GPCR signaling complexity, with implications for developing targeted cancer therapies. Her methodological innovations in membrane protein interaction studies provide valuable tools for the broader pharmacology research community.