معرفی
Ranjini Sundaram is a Researcher in the Vasquez Lab at Yale School of Medicine, focusing on cancer biology and DNA repair mechanisms. She investigates therapeutic vulnerabilities in cancers through targeted drug development, particularly in gliomas, pediatric rhabdomyosarcoma, and renal cell carcinoma. Her work emphasizes biomarker-driven strategies, enzyme inhibition (e.g., NAPRT, NAMPT, ATR), and metabolic defects. She has contributed to preclinical models of drug resistance, nanoparticle drug delivery systems, and combination therapies to enhance treatment efficacy.
- Key affiliations: Department of Therapeutic Radiology, Yale School of Medicine.
- Research themes include DNA repair pathways, radiosensitization strategies, and metabolic dependencies in cancer.
Publications highlight innovative approaches such as CRISPR-based screens for drug targets, synthetic lethality mechanisms, and translational research in brain tumor therapies. Her email is ranjini.sundaram@yale.edu for collaboration inquiries.
