معرفی
Ping Yi is an Assistant Professor in the Department of Molecular and Cellular Biology at Baylor College of Medicine, Houston, TX. He is also a member of the Dan L Duncan Comprehensive Cancer Center. His research focuses on molecular regulation of oncogene activation in cancer, including post-translational modification and signal transduction pathways. He employs transgenic mouse models, patient-derived xenograft (PDX) tumor models, and structural biology techniques like cryo-electron microscopy (Cryo-EM) to study nuclear receptor complexes.
Education includes a Ph.D. from the University of Rochester (2002-2008) and advanced training at Baylor College of Medicine. His work has explored mechanisms of ubiquitination in prostate and lung cancer, as well as structural insights into estrogen and androgen receptor complexes with coactivators.
Key research themes include cancer biology, nuclear receptor structure-function relationships, and cell signaling pathways. His recent publications highlight advancements in understanding TRAF4-mediated ubiquitination, estrogen receptor complex structures, and the role of metabolic enzymes in cancer progression.
Dr. Yi’s lab integrates structural biology with biochemical approaches to uncover novel therapeutic targets in oncology. Collaborations with institutions like the Dan L Duncan Center and use of advanced microscopy techniques underscore his interdisciplinary approach to cancer research.
