معرفی
Zhao Wang is an Associate Professor in the Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology at Baylor College of Medicine, with adjunct roles at Rice University and The University of Texas MD Anderson Cancer Center. He co-directs the CryoEM Core and is a member of the Dan L Duncan Comprehensive Cancer Center. His research focuses on structural biology and cryo-electron microscopy (cryo-EM) to study macromolecular complexes involved in antibiotic resistance, nuclear receptors, and viral structures. He holds grants from NIH-NICHD, Welch Foundation, and NIH-NIGMS.
Education: PhD from Peking University (China), MS and BS from Wuhan University (China).
Research interests include: cryo-EM techniques, membrane proteins, multidrug efflux pumps, nuclear receptor complexes, and viral structures. His lab uses cutting-edge cryo-EM and tomography to elucidate structure-function relationships in biological systems. Recent work includes resolving structures of the AcrAB-TolC efflux pump and androgen receptor coactivator complexes.
Grants include NIH funding for steroid receptor studies and Welch Foundation support for cryo-EM advancements. His lab collaborates on projects involving rotavirus structure, integrin activation, and cancer epigenetics.
Laboratory activities focus on cryo-ET, subtomogram averaging, and in situ structural analysis of biological systems. Techniques include both single-particle and tomographic approaches to study dynamic cellular processes.
