Nicholas M. Stamatos

Nicholas M. Stamatos, MD, PhD, is an Associate Professor in the Department of Medicine at the University of Maryland School of Medicine. He holds a primary appointment in Medicine and serves as a Member of the Institutional Review Board. Dr. Stamatos' academic career bridges clinical medicine and basic research, with a focus on virology and glycoimmunology.

• Education: B.A. from Boston University (1977), Ph.D. from University of Rochester School of Medicine (1987), M.D. from George Washington University School of Medicine (1991)
• Clinical Roles: HIV/Medicine inpatient service, Infectious Diseases consult services, and outpatient clinic

His research explores how carbohydrate modifications on cell surfaces influence immune cell function and HIV-1 interactions, pioneering discoveries about Neu1 sialidase localization and polysialic acid's role in dendritic cell biology. Key findings demonstrate that modulating sialic acid content can affect infection outcomes, suggesting novel therapeutic targets.

Recent publications highlight his work on semaphorin signaling in dendritic cells (2016), polysialic acid dynamics in inflammation (2014), and sialidase regulation of cytokine responses (2010). These studies span immunology, glycobiology, and neuroimmunology, focusing on dendritic cell migration, phagocytosis mechanisms, and glycosylation's impact on immune cell communication.