معرفی
Nader H. Moniri serves as Associate Dean for Research and Professor of Pharmaceutical Sciences at Mercer University College of Pharmacy, with a secondary appointment as Professor of Biomedical Sciences in the School of Medicine. His academic journey includes a B.S. in Biological Sciences from Georgia State University, a Ph.D. in Pharmaceutical Sciences from the University of North Carolina at Chapel Hill, and postdoctoral training in Pharmacology at Duke University Medical Center.
- Primary Appointment: Professor of Pharmaceutical Sciences, College of Pharmacy
- Secondary Appointment: Professor of Biomedical Sciences, School of Medicine
- Administrative Role: Associate Dean for Research, College of Pharmacy
Dr. Moniri's research focuses on molecular pharmacology and signal transduction of G protein-coupled receptors (GPCRs), particularly free-fatty acid (FFA) receptors and their roles in human health and disease. His laboratory investigates long-chain FFA receptors (FFA1/GPR40 and FFA4/GPR120) and short-chain FFA receptors (FFA2/GPR43 and FFA3/GPR41) in metabolism, neurodegeneration, inflammation, and cancers. Additional research interests include the role of reactive oxygen species (ROS) in regulating β2-adrenergic receptor function in airway disorders, molecular pharmacology of xylazine at α2-adrenergic receptors, and signaling pathways in hypertension.
Analysis of Dr. Moniri's recent publications reveals a strong focus on GPCR pharmacology, particularly FFA receptors and their implications in metabolic disorders, cancer, and neurological conditions. His work spans from basic molecular mechanisms to potential therapeutic applications, with significant contributions to understanding receptor signaling, oxidation effects on receptor function, and developing novel therapeutic approaches.
- NIH/NHLBI-funded research on ROS regulation of β2AR in airway disorders
- Collaborative NIH-funded projects on xylazine mechanisms with Dr. Clint Canal
- Multiple American Heart Association and NIH-funded projects on hypertension signaling with Dr. Raquib Hasan
- Co-founder of Channel Therapeutics for muscarinic acetylcholine receptor drug development
Dr. Moniri teaches multiple courses in the Pharm.D. curriculum including Gastrointestinal and Musculoskeletal Pharmacotherapy, Endocrine Pharmacotherapy, Nervous System Pharmacotherapy, and Infectious Disease Pharmacotherapy, covering both foundational and clinical aspects of pharmacology and medicinal chemistry.
