معرفی
Minfei Su is an Assistant Professor of Chemistry at Binghamton University. His research focuses on the structural and biochemical mechanisms of G protein-coupled receptors (GPCRs) using cryo-electron microscopy, alongside biochemical and cellular studies. The Su laboratory investigates ligand specificity, biased signaling, and drug discovery applications for GPCRs, which are critical in cardiovascular, neurological, and oncological diseases.
Dr. Su holds a PhD from North Dakota State University. His teaching responsibilities include courses such as Advanced Biochemistry (BCHM-507), Membrane Proteins (CHEM-483M/583M), and Biochemistry Laboratory (BCHM-426). He has been awarded the American Heart Association Career Development Award (2023).
His research integrates structural biology with pharmacology to uncover how GPCRs mediate cellular responses. Recent work includes structural analyses of α1A- and β1-adrenergic receptors in complex with ligands and G proteins, offering insights into signaling mechanisms. The lab also explores autophagy regulation via BECN1 and ATG14 interactions, linking structural flexibility to cellular stress responses.
Dr. Su advises students in the Biochemistry and Cellular & Molecular Biology (BCCB) program. His lab's interdisciplinary approach bridges cryo-EM, biochemistry, and pharmacology, with implications for therapeutic development targeting GPCRs.
