Miguel Ganuza

Dr. Miguel Ganuza serves as a Senior Lecturer and Group Leader at Queen Mary University of London's Centre for Haemato-Oncology, where he investigates fundamental mechanisms of haematopoietic stem cell function and their subversion in leukaemia. His academic foundation includes a BSc, MSc, and PhD, supporting his expertise in stem cell biology and cancer research.

His research spans critical themes including Cancer and Ageing, Cancer Cell Biology, Stem Cells, Tumour Microenvironment, Leukaemia, and Haematopoiesis. Dr. Ganuza's work integrates developmental biology with translational cancer research to dissect clonal evolution, stem cell exhaustion, and niche interactions in blood disorders.

His publication record reveals a consistent trajectory in murine hematopoiesis research, focusing on stem cell ontogeny, clonal dynamics during aging, and genetic regulation of stem cell maintenance. Key contributions include elucidating embryonic origins of hematopoietic stem cells and mechanisms linking cell cycle regulation to premature aging.

Dr. Ganuza's scientific excellence is recognized through prestigious awards:

• American Society of Hematology (ASH) Global Research Award (2021)
• Medical Research Council Career Development Award (2021-2025)
• Leukaemia UK John Goldman Fellowship (2020-2022)

He directs a research program supported by major grants from The Kay Kendall Leukaemia Fund (£137,792), ASH ($150,000), MRC (£1.5M), Leukaemia UK (£123,856), and Barts Charity, focusing on bone marrow niche identification and clonal haematopoiesis pathways. As Group Leader, he mentors a multidisciplinary team within the Centre for Haemato-Oncology.

His laboratory employs advanced genetic engineering and stem cell transplantation techniques to model leukemogenesis and dissect stem cell-niche interactions, positioning his research at the intersection of basic science and therapeutic development for blood cancers.