معرفی
Melanie White is an Associate Professor and group leader at the Charles Perkins Centre, University of Sydney. Her research focuses on understanding how diabetes increases heart attack risk and poor outcomes post-cardiac events. She leads the Cardiometabolic Proteomics Group, using multi-omic techniques (mass spectrometry, bioinformatics) to study diabetic cardiomyopathy and ischemia. Key roles include Secretary of the Australasian Proteomics Society and editorial board member of the Journal of Molecular and Cellular Cardiology.
Education and career milestones include NHMRC CJ Martin Fellowship (2006), DECRA (2012), and Heart Foundation Future Leader Fellowship (2019). Awards include the Paul Dudley White Award (2022) and FAHA fellowship (2022). Teaching roles include coordinating third-year pathology courses and integrating online education strategies during the pandemic.
Research emphasizes post-translational modifications (e.g., phosphorylation, redox changes) in cardiovascular diseases. Her lab develops biomarkers using Langendorff perfusion and pre-clinical models. Collaborations with Sydney Mass Spectrometry aim to enrich protein modifications for disease analysis.
- Grants: Multiple NHMRC/ARC-funded projects on metabolic dysfunction and biomarker discovery.
- Labs/Teams: Cardiometabolic Proteomics Group, cardiovascular physiology lab with ex vivo perfusion expertise.
- Future Work: Expanding multi-omic approaches to hepatic-cardiac interactions and diabetes complications.
