معرفی
Mathilde Gendrin is a Junior Group Leader at Institut Pasteur de la Guyane since 2017. Her research focuses on the critical role of mosquito microbiota in regulating vectorial capacity for malaria and other diseases, bridging laboratory and field-based approaches.
- 2019: HDR from Université de Paris
- 2010: PhD from Université Pierre et Marie Curie
- 2005: MSc from Université Pierre et Marie Curie
- 2004: MSc from ENS Lyon
Dr. Gendrin’s research explores:
- Host-pathogen-microbiota tripartite interactions
- Sex-specific nutritional requirements in mosquitoes
- B vitamin synthesis by microbiota
- Microbiota manipulation to block malaria transmission
- Vector fitness trade-offs under microbiota perturbation
The 15 most recent publications reveal a consistent theme of microbial regulation of mosquito physiology, with emphasis on gnotobiotic models, vitamin metabolism, and transmission-blocking strategies. Her work has appeared in Nature Communications, Cell Host & Microbe, and Frontiers in Microbiology.
Notable scientific contributions include:
- Establishing germ-free mosquito protocols for stage-specific studies
- Identifying biotin toxicity thresholds in Aedes aegypti
- Mapping microbiota-antibody response interactions
She collaborates with teams at Imperial College and EPFL, and her projects are funded by LabEx IBEID and ANR PILGRIM. Dr. Gendrin leads the Reshaping the microbiota of mosquitoes project to model wild microbiota in laboratory settings.
