معرفی
Louis Lambrechts is a Researcher and Head of the Insect Infection & Immunity Group at the Institut Pasteur in Paris, France, within the Department of Virology. His research focuses on the ecology, evolution, and genetics of mosquito-virus interactions, particularly involving Aedes aegypti and arboviruses such as dengue and Zika. He leads a dynamic research team and multiple national and international projects funded by agencies including ANR and EU consortia.
His research interests include arbovirus transmission dynamics, vectorial capacity, mosquito genetics, evolutionary ecology, host-pathogen interactions, and the role of microbiota in vector competence. He employs genomics, quantitative genetics, and experimental evolution to understand the mechanisms underlying variation in mosquito susceptibility to viral infection. His work has important implications for predicting and controlling arboviral disease outbreaks.
Lambrecht’s recent publications reveal key insights into the genetic and environmental factors influencing arbovirus transmission, including the role of mosquito population variation in Zika transmission in Africa, the impact of endogenous viral elements, and the discovery of antiviral roles for cytochrome P450 enzymes. His research integrates molecular biology, field studies, and computational modelling, contributing to a comprehensive understanding of vector-borne disease systems.
He has mentored numerous PhD students, postdoctoral researchers, and visiting scientists, fostering a collaborative and interdisciplinary research environment. His lab collaborates widely with institutions across Europe, Africa, and the Americas.
Lambrecht’s work is supported by multiple ongoing projects such as CAZIKANO, INTRANZIGEANT, ANR PILGRIM, and LIPOARBO-IVI, focusing on Zika virus transmission, genetic drivers of vectorial capacity, and mosquito-virus specificity. His lab is also involved in broader initiatives like the LabEx IBEID and the Emerging Infectious Diseases program at Institut Pasteur.
