معرفی
Mario Mauthe is a Researcher at the Faculty of Medical Sciences, University of Groningen, affiliated with the Protein Homeostasis (PH) research group. His work focuses on autophagy mechanisms and their role in neurodegenerative diseases.
Research Interests:
- Autophagy and selective autophagy in protein degradation
- Neurodegeneration in diseases like BPAN and MPAN
- Role of lysosomal and proteasome systems in cellular aggregates
- Therapeutic strategies targeting autophagy restoration
- Mitochondrial dysfunction and photodynamic therapy
Recent Research Trends: His publications highlight autophagy as a therapeutic target for neurodegenerative disorders, with emphasis on molecular pathways and drug discovery. Collaborations span cellular biology, neurology, and pharmacology disciplines.
Activities: He serves on the editorial board of Frontiers in Cellular and Infection Microbiology and has presented at international symposia, including the 2024 BPAN symposium and 2022 Drosophila model conference.
Dataset Contributions: Co-contributor to datasets on WDR45 gene associations and chloroquine's effects on autophagosome-lysosome fusion, hosted on figshare and University of Groningen repositories.
