معرفی
Prof. Müge Kasanmascheff holds the Professorship in EPR Spectroscopy at TU Dortmund University's Department of Chemistry and Chemical Biology. She earned her PhD in Physical Chemistry from the University of Freiburg (2012), with research experience spanning MPI for Biophysical Chemistry, Göttingen, and the University of Canterbury, New Zealand.
Her research deciphers reaction mechanisms of metalloenzymes using advanced spectroscopic techniques, with emphasis on [FeFe]-hydrogenases, cytochrome P450 systems, and DNA G-quadruplex assemblies. Key investigations explore oxygen-resistant hydrogenase radicals, electron transport in alkane-degrading enzymes, and copper-modified nucleic acid structures. Her methodological innovations include in-cell EPR spectroscopy for characterizing tyrosyl radicals and high-field ENDOR for probing DNA flexibility.
Prof. Kasanmascheff's publications demonstrate rigorous analysis of bioinorganic systems, with recent work characterizing unusual valence states in iron-sulfur clusters, radical stabilization in supramolecular cages, and triplet-state reaction intermediates. Her spectroscopic expertise provides atomic-level insights into enzyme dynamics and catalytic mechanisms across biological and chemical systems.
