جستجوی استاد راهنمای دانشگاهی

Dr. James McDonald serves as a Lecturer and Research Fellow at the University of New South Wales (UNSW) within the School of Civil and Environmental Engineering's Water Research Centre (WRC). His work at the Vallentine Annexe (H22), Room 102, Kensington Campus focuses on advancing water treatment technologies and understanding contaminant behavior in water systems. His position bridges academic instruction with cutting-edge research in environmental engineering. McDonald's research spans multiple critical areas in water science and engineering, with particular emphasis on trace organic contaminants, membrane technologies, and advanced water treatment processes. His work investigates the fate and removal of pharmaceuticals, personal care products, and industrial chemicals in various water treatment systems. He has made significant contributions to understanding disinfection by-product formation, chiral inversion of pharmaceuticals, and the development of novel membrane technologies for improved water purification. His research combines experimental approaches with computational modeling to address complex water quality challenges. Analysis of McDonald's recent publications reveals a strong focus on emerging contaminants, particularly PFAS compounds and chiral pharmaceuticals, and their behavior in water treatment systems. His work demonstrates expertise in both conventional and advanced water treatment technologies, with increasing emphasis on sustainable approaches including green infrastructure and novel membrane processes. The interdisciplinary nature of his research connects environmental engineering, chemistry, microbiology, and materials science to address contemporary water quality challenges. McDonald actively collaborates with researchers across multiple institutions and has contributed to numerous significant studies on water quality and treatment. His work supports the development of more effective water recycling systems and safer drinking water supplies. While specific grant information isn't detailed in the available text, his extensive publication record suggests sustained research funding in water treatment technologies and contaminant fate studies. As part of UNSW's Water Research Centre, McDonald contributes to one of Australia's leading water research facilities. The WRC provides a collaborative environment for addressing complex water challenges through interdisciplinary research that integrates engineering, chemistry, and environmental science perspectives.

• Water Treatment
• Membrane Technology
• Trace Organic Contaminants
• +۶ مورد دیگر

Vikramaditya G. Yadav is an Associate Professor at the University of British Columbia (UBC) in the Department of Chemical and Biological Engineering, Faculty of Applied Science. He directs the Master of Engineering Leadership (MEL) Program in Sustainable Process Engineering and leads the BioFoundry research group. Education: B.A.Sc., University of Waterloo (2007) Ph.D., Massachusetts Institute of Technology (2013) Postdoctoral Associate, Harvard University (2014) His research spans sustainable chemical manufacturing, metabolic engineering, and biotechnology. Key areas include: Designing biosynthetic enzymes for biomass valorization Developing bioremediation strategies for industrial water quality Creating innovative drug delivery systems and tissue engineering solutions Advancing synthetic biology for pharmaceutical and bioenergy applications His recent work focuses on ocular drug delivery, cannabinoid biosynthesis in E. coli, lignin-based nanoparticles for cancer therapy, and computational analysis of plant secondary metabolites. Collaborations with start-ups, industry, and medical labs drive innovation in Canada's bioeconomy. Professional Leadership: Chair, Biotechnology Division of the Chemical Institute of Canada Associate Editor, The Canadian Journal of Chemical Engineering He is affiliated with UBC's BioProducts Institute and contributes to project-based learning pedagogy.

• Biocatalysis
• Bioremediation
• Bioprocess engineering
• +۱۵ مورد دیگر

David H. Sherman is the Hans W. Vahlteich Professor of Medicinal Chemistry at the University of Michigan, holding joint appointments in the College of Pharmacy (Department of Medicinal Chemistry), Medical School (Microbiology & Immunology), and College of Literature, Science, and the Arts (Chemistry). He leads the Sherman Lab at the Life Sciences Institute and co-founded the Natural Products Discovery Core. His research focuses on natural product discovery, biosynthetic pathways, and drug development for infectious diseases, cancer, and neurological disorders. Education: PhD in Synthetic Organic Chemistry from Columbia University (1981), BA in Chemistry from UC Santa Cruz (1978). Postdoctoral research at MIT (1984). Research interests include microbial secondary metabolites, enzymatic catalysis (e.g., C-H functionalization, polyketide assembly), and high-throughput drug screening. He pioneered a microbial natural product library with over 50,000 samples. Current projects emphasize developing macrolide antibiotics and advancing compounds toward clinical trials through the Natural Products Biosciences Initiative. Collaborations span global institutions, with a focus on biodiversity conservation and capacity-building in low-income nations. He has mentored 67 PhD students, 60 postdocs, and 85+ undergraduates, fostering interdisciplinary training in chemical biology and microbial biochemistry. Labs/Teams: Sherman Lab (Life Sciences Institute), Center Member at Samuel and Jean Frankel Cardiovascular Center, Center for Computational Medicine and Bioinformatics, Rogel Cancer Center.

• Natural Products Chemistry
• Medicinal Chemistry
• Biosynthesis
• +۴ مورد دیگر

David John Procter is a Professor of Organic Chemistry and Head of the Department of Chemistry at the University of Manchester. His career includes academic roles at the University of Glasgow (Lecturer, Senior Lecturer) and a Readership at the University of Manchester, where he became a Professor in 2008. His research focuses on developing new synthetic methods, catalysis, and materials chemistry, with applications in drug discovery, biocatalysis, and organic electronics. Education: BSc Chemistry (University of Leeds, 1992), PhD (1995, supervised by Prof. Christopher Rayner). Postdoctoral work: Florida State University (Prof. Robert Holton, Taxol analog synthesis). Research interests include samarium diiodide-mediated reactions, metal-free coupling processes, and sustainable synthesis methods. He leads projects funded by EPSRC, Industry (30 grants), and international collaborations. Awards include the EPSRC Established Career Fellowship (2015–2020), Bader Prize (2014), and Young Heterocyclic Chemist Award (2015). Key contributions: Total synthesis of natural products (e.g., pleuromutilin), development of copper-catalyzed multicomponent couplings, and innovative methods for organic materials. His work aligns with UN Sustainable Development Goals related to affordable and clean energy and responsible consumption. Collaborations span academic and industrial partnerships in chemistry, physics, and biology. He supervises 60+ students and contributes to the Organic Materials Innovation Centre (OMIC). His group’s research is detailed at proctergroupresearch.com .

• Organic Synthesis
• Catalysis
• New Synthetic Methods
• +۵ مورد دیگر

John M. Woodley is a distinguished Professor in the Department of Chemical and Biochemical Engineering at the Technical University of Denmark (DTU), where he leads research at the PROSYS - Process and Systems Engineering Centre and contributes to the DTU Microbes Initiative. With over 30 years of experience, he has established himself as a leading expert in biocatalysis and bioprocess engineering, with research spanning both theoretical and experimental work across multiple scales. His primary research interests focus on the interface of bioprocess engineering, process chemistry, and reaction engineering. Dr. Woodley's work encompasses multi-step biocatalysis (including systems biocatalysis and flow chemistry), downstream processing from biocatalytic reactors and fermentations (including ISPR), modeling tools for bioprocess assessment (thermodynamics, kinetics, process simulation, economic evaluation), and bio-oxidations (including oxygen supply methods). His enzymatic investigations particularly target alcohol oxidases, carbohydrate oxidases, cytochrome P450s, Baeyer-Villiger monooxygenases, and transaminases. His research portfolio demonstrates consistent innovation in sustainable chemical production, with particular emphasis on enzymatic synthesis of pharmaceuticals and chemicals from renewable resources. Analysis of his recent publications reveals a strong focus on overcoming industrial implementation challenges, particularly regarding enzyme stability in various reactor environments, optimization of multi-enzyme systems, and scale-up methodologies for biocatalytic processes. Dr. Woodley actively supervises multiple PhD students and leads several significant research projects, including 'P450-based biocatalytic processes for the pharmaceutical industry' (2025-2028), 'Integrated model for up- and downstream bioprocess intensification' (2024-2027), and 'ENFACE: A tool for prediction of enzyme stability at gas-liquid interfaces' (2024-2027). His work has resulted in an impressive publication record of 781 research outputs across various formats, including journal articles, book chapters, and conference proceedings. His research group operates within the Department of Chemical and Biochemical Engineering at DTU, utilizing advanced facilities for biocatalysis research, including specialized reactor systems for studying gas-liquid interfaces, computational modeling resources, and laboratories for enzyme characterization and bioprocess development. Through his leadership in the PROSYS center, he contributes to DTU's strategic focus on sustainable process technologies and systems engineering.

• Biocatalysis
• Bioprocess Engineering
• Enzyme Technology
• +۶ مورد دیگر

Dr. Monica E. McCallum is an Assistant Professor of Chemistry in the Department of Chemistry at the University of Pennsylvania’s School of Arts & Sciences. Her research focuses on understanding the biochemical origins of natural products and their roles in microbial communication. She leads the McCallum Lab, which employs interdisciplinary approaches combining organic synthesis, biochemistry, microbiology, and microscopy to study microbial natural products in their native contexts. Education: 2016 – Postdoctoral Fellow at Harvard University under Prof. Emily P. Balskus 2016 – PhD in Organic Chemistry from Baylor University 2013 – PhD Candidate at Colorado State University 2011 – B.S. in Chemistry from University of California, Irvine Research Interests: Dr. McCallum’s work bridges organic synthesis and microbiology to decode microbial metabolite functions. Key themes include: Synthesizing complex natural products and their biosynthetic precursors Discovering novel enzyme-catalyzed reactions Unraveling microbial communication mechanisms via natural products Investigating environmental microbial community dynamics Lab & Collaborations: The McCallum Lab emphasizes interdisciplinary collaboration, integrating techniques from organic chemistry, molecular biology, and microscopy to study natural products in situ. Current projects focus on diazeniumdiolate biosynthesis pathways and enzymatic detoxification of marine toxins.

• Microbial Chemistry
• Natural Products Synthesis
• Biochemistry
• +۳ مورد دیگر

Ulf Hanefeld is a Full Professor and Section Leader in the Department of Biotechnology at the Faculty of Applied Sciences , Delft University of Technology (TU Delft) , where he leads the Biocatalysis research section. His work integrates chemistry and biology to develop sustainable synthetic methodologies using enzymes. PhD from Georg-August-Universität zu Göttingen (1993) Postdoctoral experience at Imperial College London, University of Cambridge, and TU Delft Recipient of a Royal Netherlands Academy of Arts and Sciences (KNAW) fellowship His research interests center on biocatalysis , particularly enzymes that enable difficult chemical transformations such as C–C bond formation , enantioselective hydration , and ozonolysis . He focuses on enzyme discovery, engineering, immobilization, and application in flow chemistry to achieve sustainable and efficient synthesis. His work spans from fundamental enzyme mechanism studies to industrial applications in green chemistry . The publication trends reveal a consistent focus on enzyme immobilization , flow reactor systems , and chemo-enzymatic cascades . His recent work emphasizes the use of hydroxynitrile lyases , aldolases , and methyltransferases for the synthesis of chiral intermediates under environmentally benign conditions. The integration of biocatalysis with continuous manufacturing highlights a strong commitment to industrial applicability and process sustainability. Scientific contributions and recognition : Active contributor to high-impact journals in chemistry and biotechnology Coordinated research in the CassaFLOW project (international academic-industrial collaboration) Author of influential reviews, e.g., in Chemical Society Reviews (2022) Teaching and supervision : He teaches Catalysis (Bachelor) and Advanced Biocatalysis (Master), and supervises numerous Master’s theses (MEP) and Bachelor’s projects (BEP) . Students in his group are actively involved in research and often become co-authors on scientific papers. Projects center on green chemistry, enzyme engineering, and spectroscopic analysis of biochemical systems. Laboratory and research environment : The Ulf Hanefeld Group operates within the Biocatalysis section, a multidisciplinary environment fostering collaboration on enzyme discovery, immobilization, and cascade reactions. The group emphasizes practical innovation, with strong links to industry and international research networks.

• Biocatalysis
• Enzyme Engineering
• Green Chemistry
• +۷ مورد دیگر

Tanja Narancic is an Assistant Professor at the School of Biomolecular and Biomedical Science at University College Dublin (UCD). She is also an academic collaborator at the Bioeconomy Research Centre BiOrbic, where she coordinates multiple research projects among PIs, PostDocs, PhD students, and designs projects proposed by industrial partners. Dr. Narancic earned her PhD in Applied Microbiology from the University of Belgrade, Serbia in 2012, followed by postdoctoral research at the Institute of Molecular Genetics and Genetic Engineering in Belgrade. In 2013, she joined University College Dublin as a Postdoctoral Research Fellow under Prof. Kevin O'Connor, where she investigated microbial metabolic pathways using proteomics, metabolomics, and synthetic biology tools as part of FP7 and H2020 projects. She became a Research Fellow at BiOrbic in 2019 before advancing to her current position as Assistant Professor. Her research focuses on elucidating bacterial metabolism and leveraging synthetic biology tools to exploit bacteria for producing high-value products. Key research areas include: Proteomics, Metabolomics, and Transcriptomics for microbial pathway analysis Metabolic engineering for bioproduction Biocatalysis and enzyme optimization Protein engineering and purification Polyhydroxyalkanoate (PHA) production from waste streams Plastic upcycling and biodegradation technologies Dr. Narancic's publication record demonstrates a strong focus on converting plastic waste into valuable biodegradable materials through innovative biotechnological approaches. Her recent work has centered on developing microbial systems for upcycling polyethylene terephthalate (PET), polyolefins, and other recalcitrant plastics into polyhydroxyalkanoates (PHAs) and other high-value products. She has made significant contributions to understanding the metabolic pathways involved in plastic monomer conversion and has developed engineered strains with enhanced capabilities for plastic upcycling. As a principal investigator, Dr. Narancic leads multiple significant research projects including the Ad Astra Studentship (2023-2028), the UPLIFT project on sustainable plastics for food packaging (2021-2025), and the PROMOFER project (2024-2028) on optimizing PHB production. She also serves as a reviewer for numerous prestigious journals including Enzyme and Microbial Technology, Journal of Applied Microbiology, and Microbial Biotechnology. Her teaching portfolio includes coordination of multiple modules such as Bioprocessing, Metabolism and Disease, and SynBio for Bioeconomy, demonstrating her commitment to educating the next generation of scientists in both fundamental and applied aspects of biomolecular science.

• Microbiology
• Biochemistry
• Synthetic and systems biology
• +۸ مورد دیگر

Dr. Jeremy Guest is the Levenick Professor in Civil and Environmental Engineering (and courtesy appointment in Chemical & Biomolecular Engineering) at the University of Illinois Urbana-Champaign (UIUC). He serves as Associate Director for Research at the Institute for Sustainability, Energy, and Environment (iSEE) and leads the Center for Advanced Bioenergy and Bioproducts Innovation (CABBI). His research focuses on advancing circular bioeconomies through sustainable sanitation systems, resource recovery from wastewater, and biofuel/bioproduct development from lignocellulosic biomass. Guest's work emphasizes Quantitative Sustainable Design (QSD) methodologies to bridge engineering innovation with policy and investment decisions. Education: PhD in Environmental Engineering (University of Michigan, 2012); MS (Virginia Tech, 2007); BS (Bucknell University, 2005). Research interests include wastewater treatment innovation, nutrient recovery, bioenergy systems design, and sustainable agriculture practices. Key contributions include the EcoRecover phosphorus recovery process, the QSDsan modeling platform, and leadership in CABBI's $262.5M DOE-funded initiative. Guest has secured funding from NSF, US EPA, USDA, and the Bill & Melinda Gates Foundation. Recognitions include the NSF CAREER Award, 2021 James J. Morgan Early Career Award, and the Paul L. Busch Award. He advises over 15 graduate students and leads multiple high-impact projects like the NEWgenerator sanitation system and oilcane biorefinery integration. Lab/Group: Guest Research Group focuses on experimental, computational, and policy-oriented research to solve global sustainability challenges. Current projects address algae-based wastewater treatment, fecal sludge management in low-income regions, and precision fermentation systems development.

• Circular Bioeconomy
• Wastewater Treatment
• Resource Recovery
• +۵ مورد دیگر

Michael Groll serves as Professor and Chair of Biochemistry at the Technical University of Munich (TUM), where he leads structural biology and enzymology research with a focus on proteasome mechanisms and inhibitor development. His laboratory, located at the Ernst-Otto-Fischer-Str. 8 campus in Garching, maintains active collaborations in drug discovery for cancer and infectious diseases. His primary research domains include proteasome inhibition, enzyme catalysis, and natural product biosynthesis, employing X-ray crystallography, biochemical assays, and bioengineering to dissect molecular mechanisms. Recent work emphasizes AI-guided enzyme optimization, bacterial stress response targeting, and structural characterization of halogenation enzymes, reflecting interdisciplinary approaches bridging chemistry and biology. Analysis of his 2023-2025 publications reveals consistent innovation in proteasome-targeted therapeutics, with 15 high-impact papers featuring structural insights into enzyme-inhibitor complexes and biosynthetic pathways. Key trends include engineering megasynthetases for immunoproteasome inhibitors, optical control of protein degradation, and elucidating metal-dependent mechanisms in antibiotic biosynthesis. No scientific awards were documented in the provided source material. While specific grant details and student mentorship records were not disclosed, his extensive publication record indicates leadership in collaborative research projects involving structural biology and chemical biology methodologies. The Chair of Biochemistry under Prof. Groll operates as a hub for structural enzymology, housing facilities for protein crystallography, enzyme kinetics, and natural product characterization. His team actively contributes to TUM's research ecosystem through partnerships with pharmaceutical groups and international structural biology consortia.

• Proteasome Research
• Structural Biology
• Enzyme Mechanisms
• +۲ مورد دیگر

Prof. Johannes A. Lercher is a retired professor (as of April 2023) at the Technical University of Munich (TUM), holding the Chair of Chemical Technology II within the Department of Chemistry. His research focuses on heterogeneous catalysis, particularly understanding catalytic processes at solid-liquid and solid-gas interfaces, with applications in sustainable energy production, CO₂ conversion, and catalytic upcycling of polymers. He has held academic positions at the University of Twente (Netherlands) and the Pacific Northwest National Laboratory (USA), and has been Editor-in-Chief of the Journal of Catalysis . His honors include the Alwin Mittasch Prize (2021), ENI Award (2016), and Kozo Tanabe Prize (2013). His recent work emphasizes low-temperature polymer upcycling, methane activation, and bioinspired catalyst design, leveraging advanced spectroscopic and operando techniques. Despite retirement, his contributions to catalysis research remain impactful. Education: PhD (1980) and Habilitation (1985), Vienna University of Technology Visiting Lecturer, Yale University (1982) Research Interests: Heterogeneous catalysis, catalytic interfaces, sustainable energy carriers, CO₂ valorization, and polymer waste upcycling. Key areas include: Design of catalysts for selective hydrocarbon synthesis Mechanistic studies using advanced spectroscopy Development of scalable catalytic processes for industrial applications Recent Trends in Publications: Focus on low-temperature polymer recycling (e.g., PVC and polyolefin upcycling), methane activation via novel catalysts (e.g., Co 2+ in ZSM-5), and bioinspired catalytic strategies. His work bridges fundamental catalysis with industrial relevance, emphasizing sustainability and energy efficiency. Awards and Recognition: Member, Academia Europaea and US National Academy of Engineering Recipient of multiple international catalysis awards (see full list above) Grants and Labs: Led the Institute for Integrated Catalysis (Pacific Northwest National Lab, 2011–present). His research groups have pioneered studies on zeolite-confined reactions and interfacial catalysis, with collaborations spanning academia and industry. Labs/Teams: Active in the TUM Department of Chemistry and international networks focused on catalytic innovation for a carbon-neutral economy.

• Catalysis
• Sustainable Energy
• Chemical Engineering
• +۳ مورد دیگر

Associate Professor LI Zhi leads the Chemical & Biomolecular Engineering Department at the National University of Singapore (NUS). His research focuses on advanced biocatalysis for sustainable manufacturing, bio-based fuels, and functional materials. He holds a PhD in Organic Chemistry from the University of Vienna (1991), an MEng from Chinese Academy of Forestry (1985), and a BSc from Nanjing University (1982). Institutional Affiliations: NUS Faculty of Engineering, NUS ChBE Department. His lab actively collaborates with global institutions like A*STAR and the Singapore Catalysis Society. Research highlights include enzyme engineering for cascade reactions, CO₂ utilization, and biomaterial synthesis. Research Interests: Discovery of novel biocatalysts, engineering of biocatalytic systems, renewable feedstock utilization, and smart material development. Recent work emphasizes cascade biotransformations for chiral chemicals and sustainable processes. Lab Activities: Hosted international conferences (e.g., Southeast Asia Catalysis Conference 2019), collaborations with industry leaders (GSK, Pfizer), and visits from distinguished researchers like Prof. Zhao Huimin. Student milestones include PhD completions (e.g., Wang Wen, Joel Choo Ping Syong) and postdoc contributions across institutions. Grants & Labs: Active in grants related to biocatalysis and green chemistry. Lab members include researchers like Dr. Nicholas Goh and PhD students Li Li. Infrastructure includes advanced facilities for biotransformations and material synthesis.

• Biocatalysis
• Green Chemistry
• Sustainable Manufacturing
• +۴ مورد دیگر

Karl Griswold is a Professor of Engineering at Dartmouth College's Thayer School of Engineering, where he leads the Griswold Research Group focused on protein engineering and biotherapeutics development. His interdisciplinary work spans chemical, biological, and engineering disciplines to address critical challenges in drug-resistant infections and protein therapeutics. Education: BS in Chemistry from Southwest Texas State University (1995) PhD in Chemistry from the University of Texas at Austin (2005) Research Focus: Professor Griswold's laboratory specializes in protein engineering, directed evolution, and biotherapeutics development , creating novel biomolecules with superior functionality compared to natural proteins. The group develops high-throughput screening methods, protein deimmunization strategies, enhanced expression systems, and antibacterial agents targeting drug-resistant infections. Their work has significant translational potential for treating conditions like MRSA and Pseudomonas aeruginosa infections. Scientific Recognition: Wallace H. Coulter Foundation Early Career Translational Research Award in Biomedical Engineering (2008) NIH Biotechnology Training Grant (2000-2003) Royston M. Roberts - Regents Fellowship, University of Texas (1999) DOW Chemical Foundation Scholar, Texas State University (1991-1995) Senior Fellow, National Academy of Inventors Research Leadership: As co-founder and CEO of Stealth Biologics, Professor Griswold translates academic research into commercial applications. His work has secured NIH funding and Dartmouth Innovations Accelerator support, with research featured in Chemical & Engineering News, Vermont Public Radio, and the New Hampshire Union Leader for developing alternatives to traditional antibiotics. Research Environment: The Griswold Research Group maintains extensive collaborations across disciplines including clinical medicine, immunology, structural biology, and chemical engineering. This interdisciplinary approach prepares trainees for careers at the intersection of multiple scientific fields, with research focusing on Biomolecular Antimicrobial Therapies, Deimmunizing Protein Therapeutics, and Gene Library Construction Technologies.

• Protein engineering
• Directed evolution
• Biotherapeutics
• +۲ مورد دیگر

Kesen Ma is an Associate Professor and Undergraduate Advisor in Biology at the University of Waterloo, specializing in hyperthermophile physiology and enzymology. His research explores metabolic processes at extreme temperatures for biofuel production, with affiliations at the Centre for Bioengineering and Biotechnology and Waterloo Centre for Microbial Research. His educational background includes: Ph.D. in Microbial Biochemistry from Philipps-Universität Marburg, Germany (1989) M.Sc. in Microbiology from Academia Sinica, Taiwan (1984) B.Sc. in Microbiology from Wuhan University, China (1982) Dr. Ma's research spans Microbiology , Biochemistry , and Renewable Energy , focusing on protein thermostability, novel metabolic pathways in extremophiles, and industrial applications of thermostable enzymes. His work bridges fundamental enzymology with practical biocatalysis for pharmaceutical and biofuel industries. Analysis of his 2017-2024 publications reveals consistent focus on alcohol dehydrogenases and pyruvate decarboxylases from thermophiles, emphasizing enzyme characterization, thermostability mechanisms, and high-temperature fermentation systems for ethanol production. His scientific recognition includes: Research Fellow at Max-Planck Institute, Philipps-Universität Marburg (1985) Graduate Scholarship from Academia Sinica, Beijing (1982) As Undergraduate Advisor for Biology, Dr. Ma mentors students while leading patented research on thermostable biocatalysts (US patent 8476051). His work has direct industrial applications in bioethanol production and stereo-specific compound synthesis. He actively collaborates through the Waterloo Centre for Microbial Research, focusing on extremophile enzymology for sustainable bioprocessing solutions.

• Microbiology
• Biochemistry and enzymology
• Protein purification and analysis
• +۹ مورد دیگر

Roberto A. Chica is a Full Professor in the Department of Chemistry and Biomolecular Sciences at the University of Ottawa, Faculty of Science. His research focuses on computational and experimental protein engineering, particularly in designing novel enzymes and fluorescent proteins for biotechnological applications. He develops advanced algorithms for protein design and investigates enzyme dynamics using molecular modeling and structural biology approaches. Key research interests include biocatalysis, structural biology, and the application of computational methods to engineer proteins with tailored functions. His lab integrates experimental protein chemistry with computational simulations to understand catalytic mechanisms and design proteins for industrial and biomedical uses. Recent work emphasizes ensemble-based computational enzyme design, exploring how conformational landscapes influence catalytic efficiency. His articles highlight advancements in artificial enzyme creation, substrate specificity modulation, and fluorescent protein optimization. Chica’s contributions bridge fundamental biochemistry with applied innovations in protein engineering. Notable achievements include the design of bright red fluorescent proteins via computational approaches and the development of biosensors for protein expression monitoring. His research has implications for drug discovery, biocatalytic synthesis, and personalized medicine.

• Protein Engineering
• Computational Protein Design
• Biocatalysis
• +۵ مورد دیگر