Loes Stevers

Loes Stevers is a researcher in the Department of Biomedical Engineering at Eindhoven University of Technology (TU/e). She earned her BSc and MSc in Biomedical Engineering at TU/e, specializing in Chemical Biology under Professor Luc Brunsveld. Her PhD work focused on developing therapeutic approaches for Cystic Fibrosis via 14-3-3 protein interactions.

• Education: BSc/MSc in Biomedical Engineering (TU/e, 2013)
• Collaborations: Kirill Alexandrov (University of Queensland), Bert Meijer, Patricia Dankers

Research Interests: Her work centers on 14-3-3 proteins, protein-protein interactions, and their role in diseases like Cystic Fibrosis. She explores supramolecular chemistry and thermodynamic models to modulate these interactions for therapeutic applications, particularly in cell membrane dynamics and CFTR activity.

Publications: Key trends include stabilizing 14-3-3 interactions with macrocycles (2022), thermodynamic modeling of multivalency (2018), and modulator development for protein interactions (2018). Her earlier work (2017) covers structural interfaces and biophysical analysis of 14-3-3 complexes.

• Labs/Teams: Worked in Brunsveld’s group (TU/e), Alexandrov’s lab (University of Queensland), and contributed to the spin-off Ambagon Therapeutics for cancer treatments