Christian Ottmann

Christian Ottmann is an Associate Professor at Eindhoven University of Technology (Biomedical Engineering) and a Principal Investigator for CRC 1093 at the University of Duisburg-Essen (Chemistry), leading Project B4 on supramolecular modulation of 14-3-3 protein interactions.

Education:

• Ph.D., Biology, Tübingen (2003)
• Diploma, Biology, Bochum (1998)

Research focuses on protein-protein interactions (14-3-3 family) using supramolecular chemistry to design molecular tools. Integrates structural biology, biophysics, and computational methods for therapeutic applications in cancer and cystic fibrosis.

His publications (2007-2020) show progression from structural studies to drug discovery, emphasizing supramolecular stabilizers/inhibitors for oncology (e.g., RAS cancers) and CFTR.

He leads Project B4 in CRC 1093, directing a team that combines synthetic chemistry, structural biology, and cell biology.